World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
8960
World Ranking
16753
National Ranking
590

Overview

Thomas E. Ichim is affiliated with the University of Western Ontario in Canada. Their research primarily spans the field of Medicine, with concentrated work in Genetics, Pulmonary and Respiratory Medicine, Molecular Biology, Rheumatology, and Oncology. The main topics of their scientific contributions include mesenchymal stem cell research, respiratory support and mechanisms, RNA interference and gene delivery, immunotherapy and immune responses, extracellular vesicles in disease, long-term effects of COVID-19, and osteoarthritis treatment and mechanisms.

The scientist has published multiple papers, with recent works including:

  • "Advancing personalized medicine in brain cancer: exploring the role of mRNA vaccines," 2023, Journal of Translational Medicine
  • "Mesenchymal stem cells as living anti-inflammatory therapy for COVID-19 related acute respiratory distress syndrome," 2020, World Journal of Stem Cells
  • "Retraction Note to: Intra-articular injection in the knee of adipose derived stromal cells (stromal vascular fraction) and platelet rich plasma for osteoarthritis," 2021, Journal of Translational Medicine
  • "Fibroblasts as an Alternative to Mesenchymal Stem Cells with Successful Treatment and Immune Modulation in EAE Model of Multiple Sclerosis," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Correction to: Scalable efficient expansion of mesenchymal stem cells in xeno free media using commercially available reagents," 2025, Journal of Translational Medicine

Thomas E. Ichim has frequently collaborated with scholars including Santosh Kesari, Boris Reznik, Anil Bajnath, Emma Lin, and Ricard Ramos. Their publications are most commonly found in the Journal of Translational Medicine, which hosts the majority of their work. Other publication venues include the Journal of Stem Cell Research & Therapeutics, World Journal of Stem Cells, bioRxiv (Cold Spring Harbor Laboratory), and Cureus.

The scientist's research focus reflects an interest in regenerative medicine and immunological therapies, emphasizing cellular interventions such as mesenchymal stem cells and fibroblasts. Their contributions to respiratory medicine and COVID-19 related therapies also highlight a multidisciplinary approach addressing acute inflammatory conditions.

Best Publications

  • Endometrial regenerative cells: A novel stem cell population

    Xiaolong Meng;Thomas E Ichim;Jie Zhong;Andrea Rogers

  • Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis

    Ashraf J. Abusamra;Zhaohui Zhong;Zhaohui Zhong;Xiufen Zheng;Mu Li

  • Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis

    Neil H Riordan;Thomas E Ichim;Wei-Ping Min;Hao-Hao Wang

  • Inhibitory Feedback Loop Between Tolerogenic Dendritic Cells and Regulatory T Cells in Transplant Tolerance

    Wei-Ping Min;Dejun Zhou;Thomas E. Ichim;Gill H. Strejan

  • Unleashing endogenous TNF-alpha as a cancer immunotherapeutic.

    Steven F. Josephs;Thomas E. Ichim;Stephen M. Prince;Santosh Kesari

  • Mesenchymal stem cells as anti-inflammatories: Implications for treatment of Duchenne muscular dystrophy

    Thomas E. Ichim;Doru T. Alexandrescu;Fabio Solano;Fabian Lara

  • Allogeneic endometrial regenerative cells: an "Off the shelf solution" for critical limb ischemia?

    Michael P Murphy;Hao Wang;Amit N Patel;Suman Kambhampati

  • Immune Modulation by Silencing IL-12 Production in Dendritic Cells Using Small Interfering RNA

    Jonathan A. Hill;Thomas E. Ichim;Thomas E. Ichim;Kornel P. Kusznieruk;Mu Li;Mu Li

  • Feasibility investigation of allogeneic endometrial regenerative cells.

    Zhaohui Zhong;Amit N. Patel;Thomas E. Ichim;Neil H. Riordan

  • RNA interference: a potent tool for gene-specific therapeutics.

    Thomas E. Ichim;Mu Li;Mu Li;Hua Qian;Hua Qian;Igor A. Popov;Igor A. Popov

  • Exosomes as a tumor immune escape mechanism: possible therapeutic implications

    Thomas E. Ichim;Zhaohui Zhong;Shalesh Kaushal;Xiufen Zheng

  • Retraction Note to: Intra-articular injection in the knee of adipose derived stromal cells (stromal vascular fraction) and platelet rich plasma for osteoarthritis

    Himanshu Bansal;Kristin Comella;Jerry Leon;Poonam Verma

  • PLGA nanoparticle-mediated delivery of tumor antigenic peptides elicits effective immune responses.

    Wenxue Ma;Mingshui Chen;Sharmeela Kaushal;Michele McElroy

  • Allogeneic stem cell transplants in non-conditioned recipients

    Thomas E. Ichim;Neil H. Riordan

  • Fibroblasts as a practical alternative to mesenchymal stem cells.

    Thomas E. Ichim;Pete O’Heeron;Santosh Kesari

  • Gene silencing of complement C5a receptor using siRNA for preventing ischemia/reperfusion injury.

    Xiufen Zheng;Xusheng Zhang;Biao Feng;Hongtao Sun

  • Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study.

    Christian Elabd;Christopher J. Centeno;John R. Schultz;Gregory Lutz

  • Treatment of lumbar degenerative disc disease-associated radicular pain with culture-expanded autologous mesenchymal stem cells: a pilot study on safety and efficacy

    Christopher Centeno;Jason Markle;Ehren Dodson;Ian Stemper

  • Stem cell therapy for autism.

    Thomas E Ichim;Fabio Solano;Eduardo Glenn;Frank Morales

  • Tumor exosomes expressing fas ligand mediate CD8+ T cell apoptosis

    C. A. O'Brien;T. E. Ichim;Z. Zhong;W. P. Min

Frequent Co-Authors

Wei-Ping Min
Wei-Ping Min Lawson Health Research Institute
Bertha Garcia
Bertha Garcia University of Western Ontario
Anthony M. Jevnikar
Anthony M. Jevnikar University of Western Ontario
Santosh Kesari
Santosh Kesari University of California, San Diego
Robert Zhong
Robert Zhong University of Western Ontario
Michael P. Murphy
Michael P. Murphy University of Cambridge
Robert D. Inman
Robert D. Inman University of Toronto
Javier Lopez
Javier Lopez University of Malaga
David H. Cribbs
David H. Cribbs University of California, Irvine
Victor V. Lobanenkov
Victor V. Lobanenkov National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

The fields of Biology and Biochemistry lay the groundwork for various specialized careers in health, research, and fitness. Many students interested in these areas may also wish to explore related online degrees that offer flexibility and focused learning.

For those interested in applied health and fitness, an exercise science and nutrition degree online provides comprehensive knowledge about body mechanics and dietary science. Similarly, kinesiology online programs emphasize the science of movement, supporting a range of careers from physical therapy to sports performance coaching.

If your interests align more with healthcare, there are also specialized pathways. The shortest online pmhnp certificate programs allow those with advanced nursing backgrounds to quickly specialize in psychiatric-mental health nursing. Alternatively, online fnp programs offer nurses a flexible route to become Family Nurse Practitioners.

These online degrees and certificates can complement a background in Biology or Biochemistry, opening diverse pathways in healthcare, research, wellness, and beyond.

Best Scientists Citing Thomas E. Ichim

Trending Scientists

Recently Published Articles