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Microbiology

D-Index
65
Citations
16248
World Ranking
2496
National Ranking
48

Overview

Sven Hoffner is affiliated with the Karolinska Institute in Sweden and has a research focus primarily in the field of Medicine, with substantial work in Infectious Diseases, Epidemiology, Surgery, Molecular Biology, and Immunology. Their research extensively covers topics related to tuberculosis and infectious diseases, with a particular emphasis on Tuberculosis Research and Epidemiology, Mycobacterium research and diagnosis, and Antibiotic Resistance in Bacteria.

The scientist's recent publications include several studies on tuberculosis and related infections. Notable papers include:

  • "Pyrazinamide Susceptibility Is Driven by Activation of the SigE-Dependent Cell Envelope Stress Response in Mycobacterium tuberculosis" (2022, mBio)
  • "Rising challenge of multidrug-resistant tuberculosis in China: a predictive study using Markov modeling" (2020, Infectious Diseases of Poverty)
  • "Atypical Genetic Basis of Pyrazinamide Resistance in Monoresistant Mycobacterium tuberculosis" (2021, Antimicrobial Agents and Chemotherapy)
  • "Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment" (2020, The Journal of Infectious Diseases)
  • "Treatment quality and outcome for multidrug-resistant tuberculosis patients in four regions of China: a cohort study" (2020, Infectious Diseases of Poverty)

The venues where Sven Hoffner frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Infectious Diseases of Poverty
  • Antimicrobial Agents and Chemotherapy
  • International Journal of Mycobacteriology
  • Zenodo (CERN European Organization for Nuclear Research)

Among frequent co-authors working with Sven Hoffner are:

  • Faramarz Valafar
  • Samuel J. Modlin
  • Jim Werngren
  • Mikael Mansjö
  • Derek Conkle-Gutierrez

The main fields of study and subfields related to Hoffner's work are characterized by a strong focus on medical research concerning infectious diseases, particularly tuberculosis. The main topics of work cover:

  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Pneumonia and Respiratory Infections
  • Cancer therapeutics and mechanisms
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Antibiotic Resistance in Bacteria
  • Infectious Diseases and Tuberculosis

Best Publications

  • A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.

    Koen Andries;Peter Verhasselt;Jerome Guillemont;Hinrich W. H. Göhlmann

  • Global trends in resistance to antituberculosis drugs. World Health Organization-International Union against Tuberculosis and Lung Disease Working Group on Anti-Tuberculosis Drug Resistance Surveillance.

    Marcos A. Espinal;Adalbert Laszlo;Lone Simonsen;Fadila Boulahbal

  • Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage

    Matthias Merker;Camille Blin;Stefano Mona;Nicolas Duforet-Frebourg

  • Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages.

    David Stucki;David Stucki;Daniela Brites;Daniela Brites;Leïla Jeljeli;Mireia Coscolla;Mireia Coscolla

  • A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis

    Paolo Miotto;Belay Tessema;Elisa Tagliani;Leonid Chindelevitch

  • Effect of rpoB Mutations Conferring Rifampin Resistance on Fitness of Mycobacterium tuberculosis

    Deneke H. Mariam;Yohannes Mengistu;Sven E. Hoffner;Dan I. Andersson

  • Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

    Abigail L. Manson;Keira A. Cohen;Keira A. Cohen;Thomas Abeel;Thomas Abeel;Christopher A. Desjardins

  • Rates and Mechanisms of Resistance Development in Mycobacterium tuberculosis to a Novel Diarylquinoline ATP Synthase Inhibitor

    E Huitric;E Huitric;P Verhasselt;Anil Koul;K Andries

  • Spread of Drug-Resistant Pulmonary Tuberculosis in Estonia

    Annika Krüüner;Annika Krüüner;Sven E. Hoffner;Heinart Sillastu;Manfred Danilovits

  • Direct susceptibility testing for multi drug resistant tuberculosis: a meta-analysis.

    Freddie Bwanga;Freddie Bwanga;Sven Hoffner;Melles Haile;Moses L Joloba

  • Fluoroquinolone Resistance in Mycobacterium tuberculosis and Mutations in gyrA and gyrB

    Andrea Von Groll;Anandi Martin;Pontus Jureen;Sven Hoffner

  • Origin and primary dispersal of the Mycobacterium tuberculosis Beijing genotype: Clues from human phylogeography

    Igor Mokrousov;Ho Minh Ly;Tatiana Otten;Nguyen Ngoc Lan

  • Extensively Drug-Resistant Tuberculosis: 2 Years of Surveillance in Iran

    Mohamad Reza Masjedi;Parissa Farnia;Setara Sorooch;Majid Valiollah Pooramiri

  • Microevolution of extensively drug-resistant tuberculosis in Russia

    Nicola Casali;Vladyslav Nikolayevskyy;Yanina Balabanova;Olga Ignatyeva

  • Rapid and Inexpensive Drug Susceptibility Testing of Mycobacterium tuberculosis with a Nitrate Reductase Assay

    K. A. Kristian Ängeby;Lisbeth Klintz;Sven E. Hoffner

  • Alarming levels of drug-resistant tuberculosis in Belarus: results of a survey in Minsk.

    Alena Skrahina;Henadz Hurevich;Aksana Zalutskaya;Evgeni Sahalchyk

  • In Vitro Antimycobacterial Spectrum of a Diarylquinoline ATP Synthase Inhibitor

    Emma Huitric;Peter Verhasselt;Koen Andries;Sven E. Hoffner;Sven E. Hoffner

  • Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project

    Matteo Zignol;Anna S. Dean;Natavan Alikhanova;Sönke Andres

  • Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis

    Pontus Juréen;Jim Werngren;Juan-Carlos Toro;Sven Hoffner

  • Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione.

    Jun Lu;Alexios Vlamis-Gardikas;Karuppasamy Kandasamy;Rong Zhao

Frequent Co-Authors

Gunilla Källenius
Gunilla Källenius Karolinska Institute
Francis Drobniewski
Francis Drobniewski Imperial College London
Stefan B. Svenson
Stefan B. Svenson Swedish University of Agricultural Sciences
Daniela M. Cirillo
Daniela M. Cirillo Vita-Salute San Raffaele University
Stefan Niemann
Stefan Niemann Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Sabine Rüsch-Gerdes
Sabine Rüsch-Gerdes Kiel University
Moses Joloba
Moses Joloba Makerere University
Sebastien Gagneux
Sebastien Gagneux University of Basel
Leen Rigouts
Leen Rigouts Institute of Tropical Medicine Antwerp
Christian G. Giske
Christian G. Giske Karolinska University Hospital

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