What is he best known for?
The fields of study he is best known for:
- Surgery
- Internal medicine
- Pathology
Seppo Santavirta mainly focuses on Surgery, Pathology, Matrix metalloproteinase, Molecular biology and Arthritis.
His study explores the link between Surgery and topics such as Granuloma that cross with problems in Total hip arthroplasty and Histiocytosis.
His studies deal with areas such as Cathepsin, Osteolysis, Cathepsin K and Synovial membrane as well as Pathology.
His work deals with themes such as Fibroblast and Interstitial collagenase, Collagenase, which intersect with Matrix metalloproteinase.
His study in Molecular biology is interdisciplinary in nature, drawing from both Nitrotyrosine, Nitric oxide synthase, Nitric oxide, Protein nitrosylation and Cartilage.
His research investigates the connection between Connective tissue and topics such as Extracellular matrix that intersect with issues in Immunohistochemistry and Giant cell.
His most cited work include:
- Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis (371 citations)
- Aggressive granulomatous lesions associated with hip arthroplasty. Immunopathological studies. (298 citations)
- Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium. (209 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Surgery, Pathology, Synovial membrane, Rheumatoid arthritis and Molecular biology.
He interconnects Collagenase, Periprosthetic and Osteolysis in the investigation of issues within Pathology.
His study in the fields of Interstitial collagenase under the domain of Collagenase overlaps with other disciplines such as Neutrophil collagenase.
His Synovial membrane research includes elements of Fibroblast and Synovitis.
His Rheumatoid arthritis research incorporates themes from Cervical spine and Arthritis.
His Immunology study incorporates themes from Peripheral blood mononuclear cell and Internal medicine.
He most often published in these fields:
- Surgery (33.33%)
- Pathology (31.87%)
- Synovial membrane (13.19%)
What were the highlights of his more recent work (between 1999-2011)?
- Pathology (31.87%)
- Surgery (33.33%)
- Synovial membrane (13.19%)
In recent papers he was focusing on the following fields of study:
Seppo Santavirta mainly investigates Pathology, Surgery, Synovial membrane, Osteolysis and Molecular biology.
His Pathology research is multidisciplinary, relying on both Receptor, Matrix metalloproteinase and Cartilage.
His Surgery research incorporates elements of Biomaterial and Coating.
Seppo Santavirta combines subjects such as Cellular immunity, Interstitial collagenase and Alkaline phosphatase with his study of Synovial membrane.
His Osteolysis research is multidisciplinary, incorporating elements of Periprosthetic, Implant, Bone resorption and Resorption.
His Molecular biology research integrates issues from Osteoclast, Cathepsin K, RANKL, Cathepsin and Immunology.
Between 1999 and 2011, his most popular works were:
- Acidic cysteine endoproteinase cathepsin K in the degeneration of the superficial articular hyaline cartilage in osteoarthritis. (142 citations)
- Operative and Nonoperative Treatments of Medial Collateral Ligament Rupture With Early Anterior Cruciate Ligament Reconstruction A Prospective Randomized Study (125 citations)
- The microenvironment around total hip replacement prostheses (121 citations)
In his most recent research, the most cited papers focused on:
- Surgery
- Internal medicine
- Radiology
Seppo Santavirta focuses on Pathology, Surgery, Matrix metalloproteinase, Periprosthetic and Osteolysis.
The various areas that Seppo Santavirta examines in his Pathology study include Cathepsin K, Synovial membrane, Cathepsin, Osteoblast and Molecular biology.
Seppo Santavirta works mostly in the field of Molecular biology, limiting it down to topics relating to Osteoprotegerin and, in certain cases, Immunology, Foreign-body giant cell, Fibroblast and Growth factor, as a part of the same area of interest.
With his scientific publications, his incorporates both Surgery and In patient.
His Matrix metalloproteinase research focuses on Bone remodeling and how it relates to Anatomy, Connective tissue, Extracellular Matrix Degradation, Extracellular matrix and Stromal cell.
His studies in Osteolysis integrate themes in fields like Immunohistochemistry, Implant, Osteoid and Bone resorption.
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