Leiden University Medical Center
Roeland W. Dirks mainly focuses on Molecular biology, Cell biology, RNA, In situ hybridization and Telomere. His Molecular biology study combines topics in areas such as Histone H3, Mitochondrial DNA, Cytogenetics, Nucleic acid thermodynamics and Transfer RNA. His Cell biology research is multidisciplinary, relying on both Hayflick limit, Biochemistry and Fluorescence microscope.
Roeland W. Dirks has included themes like Molecular beacon, Messenger RNA and Gene expression in his RNA study. He works mostly in the field of In situ hybridization, limiting it down to topics relating to Hybridization probe and, in certain cases, Fluorescence, Förster resonance energy transfer, Fluorescence in situ hybridization, Nucleic acid and Microscopy. While the research belongs to areas of Telomere, Roeland W. Dirks spends his time largely on the problem of Chromosome, intersecting his research to questions surrounding Q-FISH.
Roeland W. Dirks spends much of his time researching Molecular biology, Cell biology, RNA, In situ hybridization and Gene expression. His Molecular biology study combines topics from a wide range of disciplines, such as Fluorescence in situ hybridization and Messenger RNA, Gene, Intron. His Cell biology research integrates issues from Cell and Nuclear lamina.
His work deals with themes such as Molecular beacon, Nucleolus, Transcription and DNA, which intersect with RNA. His In situ hybridization research includes themes of Hybridization probe, Hapten, Oligonucleotide and Biotin. His Hybridization probe course of study focuses on Nucleic acid and Regulation of gene expression.
His main research concerns Cell biology, Senescence, Molecular biology, Cell nucleus and Fibroblast. He has researched Cell biology in several fields, including Cell, Green fluorescent protein, RNA transport, Bimolecular fluorescence complementation and Programmed cell death. The Senescence study combines topics in areas such as Oxidative stress, Rotenone, Apoptosis, Reactive oxygen species and Telomere.
His Molecular biology research incorporates elements of Wnt signaling pathway, Gene expression profiling, Microarray, Myocyte and Cell cycle. His study looks at the intersection of Cell nucleus and topics like DNA with Nucleic acid. In his research, Gene expression is intimately related to RNA, which falls under the overarching field of Peptide nucleic acid.
His scientific interests lie mostly in Senescence, Cell nucleus, Cell biology, Telomere and Molecular biology. The concepts of his Senescence study are interwoven with issues in Cell, Apoptosis, Programmed cell death, Lamina and Nuclear lamina. The study incorporates disciplines such as Live cell imaging, Nuclear matrix, Chromatin, Green fluorescent protein and Splicing factor in addition to Cell nucleus.
The various areas that he examines in his Cell biology study include Histone H4, Hayflick limit and RNA splicing. His Telomere study necessitates a more in-depth grasp of DNA. Many of his research projects under Molecular biology are closely connected to Bafilomycin with Bafilomycin, tying the diverse disciplines of science together.
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Heterogeneity in Telomere Length of Human Chromosomes
Peter M. Lansdorp;Nico P. Verwoerd;Frans M. van de Rijke;Visia Dragowska.
Human Molecular Genetics (1996)
Regulation of sexual development of Plasmodium by translational repression.
Gunnar R. Mair;Joanna A. M. Braks;Lindsey S. Garver;Joop C. A. G. Wiegant.
Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2
Erik Meulmeester;Madelon M. Maurice;Chris Boutell;Amina F.A.S. Teunisse.
Molecular Cell (2005)
Use of whole cosmid cloned genomic sequences for chromosomal localization by non-radioactive in situ hybridization.
Landegent Je;Jansen in de Wal N;Dirks Rw;Dirks Rw;Baao F.
Human Genetics (1987)
Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development.
Gunnar R. Mair;Edwin Lasonder;Lindsey S. Garver;Lindsey S. Garver;Blandine M. D. Franke-Fayard.
PLOS Pathogens (2010)
Visualizing telomere dynamics in living mammalian cells using PNA probes.
Chris Molenaar;Karien Wiesmeijer;Nico P. Verwoerd;Shadi Khazen.
The EMBO Journal (2003)
Linear 2′ O-Methyl RNA probes for the visualization of RNA in living cells
C. Molenaar;S. A. Marras;J. C. M. Slats;J.-C. Truffert.
Nucleic Acids Research (2001)
Mutational Analysis of Fibrillarin and Its Mobility in Living Human Cells
Sabine Snaar;Karien Wiesmeijer;Aart G. Jochemsen;Hans J. Tanke.
Journal of Cell Biology (2000)
Poly(A)+ RNAs roam the cell nucleus and pass through speckle domains in transcriptionally active and inactive cells
Chris Molenaar;Abadir Abdulle;Aarti Gena;Hans J. Tanke.
Journal of Cell Biology (2004)
Methods for visualizing RNA processing and transport pathways in living cells.
Roeland W. Dirks;Chris Molenaar;Hans J. Tanke.
Histochemistry and Cell Biology (2001)
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