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Genetics

D-Index
71
Citations
14972
World Ranking
2217
National Ranking
82

Overview

Karoly Szuhai is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions spanning related subfields including Molecular Biology, Rheumatology, Pulmonary and Respiratory Medicine, Oral Surgery, and Oncology.

The scientist has contributed extensively to topics such as Sarcoma Diagnosis and Treatment, Bone Tumor Diagnosis and Treatments, Oral and Maxillofacial Pathology, Cancer Genomics and Diagnostics, CRISPR and Genetic Engineering, Soft tissue tumor case studies, and Epigenetics and DNA Methylation.

Karoly Szuhai's recent publications illustrate a focus on cancer biology, molecular pathology, and therapeutic resistance mechanisms. Notable papers include:

  • "Translocase of the outer mitochondrial membrane complex subunit 20 (TOMM20) facilitates cancer aggressiveness and therapeutic resistance in chondrosarcoma," 2020, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  • "Expanding the Spectrum of EWSR1-NFATC2-rearranged Benign Tumors," 2021, The American Journal of Surgical Pathology
  • "Nodular fasciitis: a comprehensive, time-correlated investigation of 17 cases," 2021, Modern Pathology
  • "Unraveling the Resistance of IGF-Pathway Inhibition in Ewing Sarcoma," 2020, Cancers
  • "Tenosynovial giant cell tumors (TGCT): molecular biology, drug targets and non-surgical pharmacological approaches," 2022, Expert Opinion on Therapeutic Targets

Szuhai has frequently published in several scientific venues, most notably in:

  • The American Journal of Surgical Pathology
  • Cancers
  • Modern Pathology
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)

The researcher collaborates often with colleagues including Judith V.M.G. Bovée, Inge H. Briaire-de Bruijn, Arjen H.G. Cleven, Sheena L. M. Ong, and Hans J. Baelde.

Best Publications

  • Sarcoma derived from cultured mesenchymal stem cells

    Jakub Tolar;Alma J. Nauta;Mark J. Osborn;Angela Panoskaltsis Mortari

  • Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations

    Aniek Janssen;Marja van der Burg;Karoly Szuhai;Geert J. P. L. Kops

  • Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome

    Twinkal C. Pansuriya;Ronald van Eijk;Pio d'Adamo;Maayke A. J. H. van Ruler

  • The carcinoma–stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage

    Wilma E. Mesker;Jan M. C. Junggeburt;Karoly Szuhai;Pieter de Heer

  • Opening the archives for state of the art tumour genetic research: sample processing for array-CGH using decalcified, formalin-fixed, paraffin-embedded tissue-derived DNA samples.

    Danielle M. de Jong;Sofie Lj Verbeke;Danielle Meijer;Pancras Cw Hogendoorn

  • Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2.

    Alexander B Mohseny;Karoly Szuhai;Salvatore Romeo;Emilie P Buddingh

  • Array-CGH detection of micro rearrangements in mentally retarded individuals: clinical significance of imbalances present both in affected children and normal parents

    Carla Rosenberg;Carla Rosenberg;J. Knijnenburg;E. Bakker;A. M. Vianna-Morgante

  • Oncogenomic analysis of mycosis fungoides reveals major differences with Sézary syndrome

    Remco van Doorn;Marloes S. van Kester;Remco Dijkman;Maarten H. Vermeer

  • Novel and highly recurrent chromosomal alterations in Sézary syndrome.

    Maarten H. Vermeer;Remco van Doorn;Remco Dijkman;Xin Mao

  • The NFATc2 gene is involved in a novel cloned translocation in a Ewing sarcoma variant that couples its function in immunology to oncology.

    Károly Szuhai;Marije IJszenga;Danielle de Jong;Apollon Karseladze

  • EWSR1-CREB1 and EWSR1-ATF1 Fusion Genes in Angiomatoid Fibrous Histiocytoma

    Sabrina Rossi;Kàroly Szuhai;Marije Ijszenga;Hans J Tanke

  • Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study.

    Nadège Presneau;Asem Shalaby;Hongtao Ye;Nischalan Pillay

  • Mutation Analysis of H3F3A and H3F3B as a Diagnostic Tool for Giant Cell Tumor of Bone and Chondroblastoma

    Arjen H.G. Cleven;Saskia Höcker;Inge Briaire-de Bruijn;Karoly Szuhai

  • Peters Plus Syndrome Is Caused by Mutations in B3GALTL, a Putative Glycosyltransferase

    Saskia A.J. Lesnik Oberstein;Marjolein Kriek;Stefan J. White;Margot E. Kalf

  • Guidelines for molecular karyotyping in constitutional genetic diagnosis.

    Joris Robert Vermeesch;Heike Fiegler;Nicole de Leeuw;Karoly Szuhai

  • Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium

    Anke M. Smits;Linda W. van Laake;Linda W. van Laake;Krista den Ouden;Chantal Schreurs

  • Gene-expression profiling and array-based CGH classify CD4+CD56+ hematodermic neoplasm and cutaneous myelomonocytic leukemia as distinct disease entities

    Remco Dijkman;Remco van Doorn;Károly Szuhai;Rein Willemze

  • Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients.

    Wilma E. Mesker;Gerrit-Jan Liefers;Jan M. C. Junggeburt;Gabi W. van Pelt

  • Real‐time monitoring of rolling‐circle amplification using a modified molecular beacon design

    Mats Nilsson;Mats Gullberg;Fredrik Dahl;Karoly Szuhai

  • Cathepsin K Is the Principal Protease in Giant Cell Tumor of Bone

    Jan H.N. Lindeman;Roeland Hanemaaijer;Adri Mulder;P.D. Sander Dijkstra

Frequent Co-Authors

Pancras C.W. Hogendoorn
Pancras C.W. Hogendoorn Leiden University Medical Center
Judith V.M.G. Bovée
Judith V.M.G. Bovée Leiden University Medical Center
Hans J. Tanke
Hans J. Tanke Leiden University Medical Center
Carla Rosenberg
Carla Rosenberg Universidade de São Paulo
Anton K. Raap
Anton K. Raap Leiden University Medical Center
Cornelis P. Tensen
Cornelis P. Tensen Leiden University Medical Center
Fredrik Mertens
Fredrik Mertens Lund University
Adrienne M. Flanagan
Adrienne M. Flanagan University College London
Rein Willemze
Rein Willemze Leiden University Medical Center

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