His primary scientific interests are in Biochemistry, Peptide, Dermaseptin, Antimicrobial peptides and Peptide sequence. Pierre Nicolas interconnects Stereochemistry and Function in the investigation of issues within Biochemistry. His Peptide study incorporates themes from Residue, Biological activity and Gene.
His biological study spans a wide range of topics, including Vesicle, Membrane, Phospholipid and In vitro. In his research on the topic of Antimicrobial peptides, Antibacterial agent and Zoology is strongly related with Phyllomedusinae. His study in the field of Temporin is also linked to topics like Frog Skin.
Pierre Nicolas mostly deals with Biochemistry, Peptide, Dermaseptin, Stereochemistry and Antimicrobial peptides. When carried out as part of a general Biochemistry research project, his work on Peptide sequence, Amino acid, Neurophysins and Binding site is frequently linked to work in Frog Skin, therefore connecting diverse disciplines of study. His studies in Peptide integrate themes in fields like Neuropeptide, Molecular biology, Micelle and Residue.
His Dermaseptin study integrates concerns from other disciplines, such as Membrane, In vitro and Circular dichroism. His Stereochemistry research is multidisciplinary, relying on both Tripeptide, Receptor, Dermorphin, Conformational isomerism and Deltorphin I. His Antimicrobial peptides research includes elements of Phyllomedusa bicolor and Phyllomedusinae.
His primary areas of study are Biochemistry, Dermaseptin, Antimicrobial peptides, Peptide and Stereochemistry. His work in the fields of Intracellular, Amino acid and Membrane overlaps with other areas such as Frog Skin. His study with Dermaseptin involves better knowledge in Peptide sequence.
His Antimicrobial peptides research entails a greater understanding of Microbiology. Pierre Nicolas combines subjects such as Genetics, Antimicrobial and Circular dichroism with his study of Peptide. His Stereochemistry research incorporates elements of Protein structure, Crystallography, Micelle and Dermorphin.
Pierre Nicolas spends much of his time researching Antimicrobial peptides, Dermaseptin, Peptide, Biochemistry and Peptide sequence. His research integrates issues of Molecular cloning and Phyllomedusa bicolor in his study of Antimicrobial peptides. His Dermaseptin research is multidisciplinary, incorporating elements of Biophysics, Membrane, Bilayer and Beta defensin.
The concepts of his Peptide study are interwoven with issues in Antimicrobial, Gene, Coding region, Circular dichroism and Peptide library. Pierre Nicolas merges Biochemistry with Frog Skin in his research. His Peptide sequence study incorporates themes from Zoology, Phyllomedusinae, Subfamily and Antibacterial agent.
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PEPTIDES AS WEAPONS AGAINST MICROORGANISMS IN THE CHEMICAL DEFENSE SYSTEM OF VERTEBRATES
Pierre Nicolas;Amram Mor.
Annual Review of Microbiology (1995)
Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes.
Yehonathan Pouny;Doron Rapaport;Amram Mor;Pierre Nicolas.
Multifunctional host defense peptides: intracellular-targeting antimicrobial peptides.
FEBS Journal (2009)
The vertebrate peptide antibiotics dermaseptins have overlapping structural features but target specific microorganisms.
Amram Mor;Khaled Hani;P. Nicolas.
Journal of Biological Chemistry (1994)
Precursors for peptide hormones share common secondary structures forming features at the proteolytic processing sites
Mohamed Rholam;Pierre Nicolas;Paul Cohen.
FEBS Letters (1986)
Isolation and structure of novel defensive peptides from frog skin
Amram Mor;Pierre Nicolas.
FEBS Journal (1994)
The NH2-terminal alpha-helical domain 1-18 of dermaseptin is responsible for antimicrobial activity.
Amram Mor;P. Nicolas.
Journal of Biological Chemistry (1994)
SPECTRUM OF ANTIMICROBIAL ACTIVITY AND ASSEMBLY OF DERMASEPTIN-B AND ITS PRECURSOR FORM IN PHOSPHOLIPID MEMBRANES
Jacob Strahilevitz;Amram Mor;Pierre Nicolas;Yechiel Shai.
Covalent Structure, Synthesis, and Structure-Function Studies of Mesentericin Y 10537, a Defensive Peptide from Gram-positive Bacteria Leuconostoc mesenteroides
Yannick Fleury;Manal Abdel Dayem;Manal Abdel Dayem;Jean Jacques Montagne;Eddy Chaboisseau.
Journal of Biological Chemistry (1996)
The dermaseptin superfamily: a gene-based combinatorial library of antimicrobial peptides.
Pierre Nicolas;Chahrazade El Amri.
Biochimica et Biophysica Acta (2009)
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