Richard Appleton

Overview

Best Publications

• The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.

  Anthony G Marson;Asya M Al-Kharusi;Muna Alwaidh;Richard Appleton

  1165
  Citations

• The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial

  Anthony G Marson;Asya M Al-Kharusi;Muna Alwaidh;Richard Appleton

  1099
  Citations

• Safety and efficacy of buccal midazolam versus rectal diazepam for emergency treatment of seizures in children: a randomised controlled trial.

  John McIntyre;Sue Robertson;Elizabeth Norris;Richard Appleton

  550
  Citations

• Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome.

  Orrin Devinsky;Anup D. Patel;Elizabeth A. Thiele;Matthew H. Wong

  498
  Citations

• Febrile seizures: an update

  C Waruiru;R Appleton

  444
  Citations

• THE TREATMENT OF SLEEP DISORDERS WITH MELATONIN

  J E Jan;H Espezel;R E Appleton

  394
  Citations

• Randomised, Placebo‐Controlled Study of Vigabatrin as First‐Line Treatment of Infantile Spasms

  R. E. Appleton;A. C. B. Peters;J. P. Mumford;D. E. Shaw

  295
  Citations

• Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children.

  Amy McTague;Timothy Martland;Richard Appleton

  280
  Citations

• Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial.

  P Gringras;C Gamble;A P Jones;L Wiggs

  246
  Citations

• Nonconvulsive status epilepticus: Epilepsy Research Foundation Workshop Reports

  Matthew Walker;Helen Cross;Shelagh Smith;Camilla Young

  241
  Citations

• Dravet syndrome as epileptic encephalopathy: evidence from long-term course and neuropathology

  Claudia B. Catarino;Joan Y.W. Liu;Ioannis Liagkouras;Vaneesha S. Gibbons

  240
  Citations

• Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial

  Mark D. Lyttle;Mark D. Lyttle;Naomi E A. Rainford;Carrol. Gamble;Shrouk. Messahel

  240
  Citations

• Seizures and Encephalitis in Myelin Oligodendrocyte Glycoprotein IgG Disease vs Aquaporin 4 IgG Disease

  Shahd H. M. Hamid;Dan Whittam;Mariyam Saviour;Amal Alorainy

  224
  Citations

• The relationship between treatment with valproate, lamotrigine, and topiramate and the prognosis of the idiopathic generalised epilepsies

  A Nicolson;R E Appleton;D W Chadwick;D F Smith

  222
  Citations

• LORAZEPAM VERSUS DIAZEPAM IN THE ACUTE TREATMENT OF EPILEPTIC SEIZURES AND STATUS EPILEPTICUS

  R Appleton;A Sweeney;I Choonara;J Robson

  220
  Citations

• The treatment of convulsive status epilepticus in children. The Status Epilepticus Working Party, Members of the Status Epilepticus Working Party.

  R Appleton;I Choonara;T Martland;B Phillips

  203
  Citations

• Molecular mechanisms and phenotypic variation in RYR1-related congenital myopathies

  Haiyan Zhou;Heinz Jungbluth;Caroline A. Sewry;Lucy Feng

  197
  Citations

• The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.

  Anthony Marson;Girvan Burnside;Richard Appleton;Dave Smith

  195
  Citations

• A review of the current literature and a guide to the early diagnosis of autoimmune disorders associated with neuromyelitis optica

  Anand Iyer;Liene Elsone;Richard Appleton;Anu Jacob

  179
  Citations

• The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.

  Anthony Marson;Girvan Burnside;Richard Appleton;Dave Smith

  177
  Citations

• Gabapentin as Add‐On Therapy in Children with Refractory Partial Seizures: A 12‐Week, Multicentre, Double‐Blind, Placebo‐Controlled Study

  Richard Appleton;Klaus Fichtner;Linda LaMoreaux;Jeannine Alexander

  169
  Citations

• Best practice guidelines for the management of women with epilepsy

  P Crawford;R Appleton;T Betts;J Duncan

  164
  Citations

• Role of intravenous immunoglobulin in the treatment of acute relapses of neuromyelitis optica: experience in 10 patients

  Liene Elsone;Jay Panicker;Kerry Mutch;Mike Boggild

  161
  Citations

• Migrating partial seizures of infancy: expansion of the electroclinical, radiological and pathological disease spectrum.

  Amy McTague;Amy McTague;Richard Appleton;Shivaram Avula;J. Helen Cross;J. Helen Cross

  160
  Citations