Gibran Hemani

Overview

Best Publications

• The MR-Base platform supports systematic causal inference across the human phenome

  Gibran Hemani;Jie Zheng;Benjamin Elsworth;Kaitlin H Wade

  5462
  Citations

• Mendelian randomization: genetic anchors for causal inference in epidemiological studies

  George Davey Smith;Gibran Hemani

  3578
  Citations

• Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

  David M. Howard;Mark J. Adams;Toni Kim Clarke;Jonathan D. Hafferty

  2669
  Citations

• Defining the role of common variation in the genomic and biological architecture of adult human height

  Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  2210
  Citations

• Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

  Urmo Võsa;Annique Claringbould;Annique Claringbould;Harm-Jan Westra;Marc Jan Bonder

  2003
  Citations

• Orienting the causal relationship between imprecisely measured traits using GWAS summary data.

  Gibran Hemani;Kate Tilling;George Davey Smith

  1783
  Citations

• LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

  Jie Zheng;Mesut A. Erzurumluoglu;Benjamin L. Elsworth;John P. Kemp

  1225
  Citations

• Evaluating the potential role of pleiotropy in Mendelian randomization studies.

  Gibran Hemani;Jack Bowden;George Davey Smith

  1134
  Citations

• Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score

  Qingyuan Zhao;Jingshu Wang;Gibran Hemani;Jack Bowden

  960
  Citations

• Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.

  Jian Yang;Andrew Bakshi;Zhihong Zhu;Gibran Hemani;Gibran Hemani

  848
  Citations

• Recent Developments in Mendelian Randomization Studies

  Jie Zheng;Denis Baird;Maria-Carolina Borges;Jack Bowden

  836
  Citations

• Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

  Richard Karlsson Linnér;Richard Karlsson Linnér;Pietro Biroli;Edward Kong;S. Fleur W. Meddens;S. Fleur W. Meddens

  808
  Citations

• Improved Heritability Estimation from Genome-wide SNPs

  Doug Speed;Gibran Hemani;Michael R. Johnson;David J. Balding

  739
  Citations

• Collider bias undermines our understanding of COVID-19 disease risk and severity

  Gareth J. Griffith;Tim T. Morris;Matthew J. Tudball;Annie Herbert

  722
  Citations

• The MRC IEU OpenGWAS data infrastructure

  Ben Elsworth;Matthew Lyon;Matthew Lyon;Tessa Alexander;Yi Liu

  696
  Citations

• Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique.

  Fernando Pires Hartwig;Neil Martin Davies;Gibran Hemani;George Davey Smith

  646
  Citations

• Systematic identification of genetic influences on methylation across the human life course

  Tom R. Gaunt;Hashem A. Shihab;Gibran Hemani;Josine L. Min

  574
  Citations

• Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.

  Jie Zheng;Valeriia Haberland;Denis A Baird;Venexia M Walker

  524
  Citations

• Collider bias undermines our understanding of COVID-19 disease risk and severity

  Gareth J Griffith;Tim T Morris;Matt Tudball;Annie Herbert

  75
  Citations

• Mendelianrandomization:geneticanchorsforcausal inference in epidemiological studies

  George Davey Smith;Gibran Hemani

  0
  Citations