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Biology and Biochemistry

D-Index
57
Citations
15406
World Ranking
13627
National Ranking
971

Overview

Rainer Spang is affiliated with the University of Regensburg in Germany. Their research spans mainly the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a specialized focus on Molecular Biology, Pathology and Forensic Medicine, Oncology, Cancer Research, and Statistics and Probability.

The scientist's work encompasses several key topics, including:

  • Lymphoma Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Single-cell and spatial transcriptomics
  • Genetic factors in colorectal cancer
  • CAR-T cell therapy research
  • Tensor decomposition and applications

Rainer Spang has published research in a variety of venues where multiple works have appeared, including:

  • arXiv (Cornell University)
  • Bioinformatics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Computational Biology

Recent notable publications include:

  • "Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1," 2020, Nature Communications
  • "An overview and a roadmap for artificial intelligence in hematology and oncology," 2023, Journal of Cancer Research and Clinical Oncology
  • "Virus-specific memory T cell responses unmasked by immune checkpoint blockade cause hepatitis," 2021, Nature Communications
  • "Epstein-Barr virus status of sporadic Burkitt lymphoma is associated with patient age and mutational features," 2021, British Journal of Haematology
  • "Comparison of Patellofemoral Kinematics and Stability After Medial Patellofemoral Ligament and Medial Quadriceps Tendon-Femoral Ligament Reconstruction," 2020, The American Journal of Sports Medicine

Throughout their career, Rainer Spang has collaborated frequently with a group of co-authors, among whom are:

  • Michael Altenbuchinger
  • Rudolf Schill
  • Lars Grasedyck
  • Maren Klever
  • Tilo Wettig

Best Publications

  • Predicting the clinical status of human breast cancer by using gene expression profiles.

    Mike West;Carrie Blanchette;Holly Dressman;Erich Huang

  • A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling

    Michael Hummel;Stefan Bentink;Hilmar Berger;Wolfram Klapper

  • Role for E2F in Control of Both DNA Replication and Mitotic Functions as Revealed from DNA Microarray Analysis

    Seiichi Ishida;Erich Huang;Harry Zuzan;Rainer Spang

  • Early dissemination seeds metastasis in breast cancer

    Hedayatollah Hosseini;Milan M. S. Obradović;Martin Hoffmann;Kathryn L. Harper

  • Inferring cellular networks – a review

    Florian Markowetz;Florian Markowetz;Rainer Spang

  • Metagenomic Analysis of the Stool Microbiome in Patients Receiving Allogeneic Stem Cell Transplantation: Loss of Diversity Is Associated with Use of Systemic Antibiotics and More Pronounced in Gastrointestinal Graft-versus-Host Disease

    Ernst Holler;Peter Butzhammer;Karin Schmid;Christian Hundsrucker

  • T cells become licensed in the lung to enter the central nervous system

    Francesca Odoardi;Christopher Sie;Kristina Streyl;Vijay K. Ulaganathan

  • Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

    Julia Richter;Matthias Schlesner;Steve Hoffmann;Markus Kreuz

  • From hype to reality: data science enabling personalized medicine

    Holger Fröhlich;Rudi Balling;Niko Beerenwinkel;Oliver Kohlbacher

  • Transcriptional Profiles of CD133+ and CD133− Glioblastoma-Derived Cancer Stem Cell Lines Suggest Different Cells of Origin

    Claudio Lottaz;Dagmar Beier;Katharina Meyer;Praveen Kumar

  • Translocations activating IRF4 identify a subtype of germinal-center-derived B-cell lymphoma affecting predominantly children and young adults

    Itziar Salaverria;Claudia Philipp;Ilske Oschlies;Christian W. Kohler

  • Adjusting microbiome profiles for differences in microbial load by spike-in bacteria

    Frank Stämmler;Joachim Gläsner;Andreas Hiergeist;Ernst Holler

  • Gene Expression Signatures for Tumor Progression, Tumor Subtype, and Tumor Thickness in Laser-Microdissected Melanoma Tissues

    Jochen Jaeger;Dirk Koczan;Hans Juergen Thiesen;Saleh M. Ibrahim

  • Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells

    Oksana Voloshanenko;Gerrit Erdmann;Taronish D. Dubash;Iris Augustin

  • State-of-the art data normalization methods improve NMR-based metabolomic analysis.

    Stefanie M. Kohl;Matthias S. Klein;Jochen Hochrein;Peter J. Oefner

  • A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma.

    Itziar Salaverria;Itziar Salaverria;Idoia Martin-Guerrero;Idoia Martin-Guerrero;Rabea Wagener;Markus Kreuz

  • Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients.

    Andreas Teufel;Timo Itzel;Wiebke Erhart;Mario Brosch

  • Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome

    Daniela Weber;Peter J. Oefner;Andreas Hiergeist;Josef Koestler

  • Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma

    Sietse M. Aukema;Sietse M. Aukema;Markus Kreuz;Christian W Kohler;Maciej Rosolowski

  • Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma.

    Wolfram Klapper;Markus Kreuz;Christian W. Kohler;Birgit Burkhardt

Frequent Co-Authors

Peter J. Oefner
Peter J. Oefner University of Regensburg
Wolfram Klapper
Wolfram Klapper Kiel University
Reiner Siebert
Reiner Siebert University of Ulm
German Ott
German Ott Robert Bosch (Germany)
Lorenz Trümper
Lorenz Trümper University of Göttingen
Harald Stein
Harald Stein Charité - University Medicine Berlin
Andreas Rosenwald
Andreas Rosenwald University of Würzburg
Peter Möller
Peter Möller University of Ulm
Ralf Küppers
Ralf Küppers University of Duisburg-Essen
Ernst Holler
Ernst Holler University of Regensburg

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