Melvin I. Simon spends much of his time researching Biochemistry, G protein, Genetics, Signal transduction and Peptide sequence. His G12/G13 alpha subunits and G alpha subunit study, which is part of a larger body of work in Biochemistry, is frequently linked to Dynamical systems theory, Mitochondrial pyruvate transport and PKM2, bridging the gap between disciplines. His studies deal with areas such as Tyrosine kinase, Plasma protein binding and Pleckstrin homology domain as well as G protein.
Melvin I. Simon combines subjects such as Histidine kinase, Histidine, Neurospora crassa and Fungal protein with his study of Signal transduction. His Peptide sequence study incorporates themes from Nucleic acid sequence, Protein subunit, SCN3A and Transducin. His work in Nucleic acid sequence covers topics such as Gene product which are related to areas like Molecular biology.
Melvin I. Simon mainly focuses on Molecular biology, Gene, Biochemistry, Genetics and Cell biology. The study incorporates disciplines such as Flagellum, Gamma subunit, Molecular cloning, Gene expression and ATP synthase alpha/beta subunits in addition to Molecular biology. His study in Peptide sequence, G protein, Amino acid, Chemotaxis and G alpha subunit is done as part of Biochemistry.
His biological study spans a wide range of topics, including Nucleic acid sequence, Protein subunit and Transducin. The concepts of his Chemotaxis study are interwoven with issues in Cytoplasm, Methylation, Molecular mass and Membrane protein. His Cell biology research includes elements of Cell culture and Regulation of gene expression.
The scientist’s investigation covers issues in Cell biology, Molecular biology, Gene, Genetics and Signal transduction. When carried out as part of a general Cell biology research project, his work on Heterotrimeric G protein, Phosphorylation and Gq alpha subunit is frequently linked to work in Flexibility, therefore connecting diverse disciplines of study. His Molecular biology study combines topics in areas such as Retinal degeneration, Immune tolerance and B cell.
His research in the fields of Gene expression, Noncoding DNA and Nanoarchaeum equitans overlaps with other disciplines such as Nanoarchaeota. His study in the field of Genome, Phylogenetics, Mutation rate and Untranslated region is also linked to topics like Eukaryotic translation. His Signal transduction research includes themes of Gene targeting, Protein subunit, Saccharomyces cerevisiae and Fibroblast.
Melvin I. Simon mainly investigates Biochemistry, Gene, G protein, Genome and Genetics. In the field of Biochemistry, his study on Membrane transport protein, Inner mitochondrial membrane and Cellular respiration overlaps with subjects such as Dynamical systems theory and Glucose uptake. The Gene study combines topics in areas such as RGS Proteins, Molecular biology, Regulator of G protein signaling and RGS9.
His G protein study is related to the wider topic of Cell biology. The Whole genome sequencing research he does as part of his general Genome study is frequently linked to other disciplines of science, such as Eukaryotic translation, therefore creating a link between diverse domains of science. Pyrobaculum, Phenotype, Archaea, Ignicoccus and Pseudogene are the core of his Genetics study.
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Robust perfect adaptation in bacterial chemotaxis through integral feedback control.
Tau-Mu Yi;Yun Huang;Melvin I. Simon;John Doyle.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Flagellar rotation and the mechanism of bacterial motility.
Michael Silverman;Michael Silverman;Melvin Simon.
The genome of Nanoarchaeum equitans: Insights into early archaeal evolution and derived parasitism
Elizabeth Waters;Michael J. Hohn;Ivan Ahel;David E. Graham.
Proceedings of the National Academy of Sciences of the United States of America (2003)
G protein-coupled signal transduction pathways for interleukin-8
Dianqing Wu;Gregory J. LaRosa;Melvin I. Simon.
Repetitive Segmental Structure of the Transducin β Subunit: Homology with the CDC4 Gene and Identification of Related mRNAs
Henry K. W. Fong;James B. Hurley;Rosemary S. Hopkins;Ryn Miake-Lye.
Proceedings of the National Academy of Sciences of the United States of America (1986)
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms
Noritaka Imamachi;Goon Ho Park;Hyosang Lee;David J. Anderson.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Activation of G12/G13 Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets
Birgit Klages;Ursula Brandt;Melvin I. Simon;Günter Schultz.
Journal of Cell Biology (1999)
The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement
Rockford K. Draper;Melvin I. Simon.
Journal of Cell Biology (1980)
Association of mitochondria with microtubules in cultured cells.
Michael H. Heggeness;Melvin Simon;S. J. Singer.
Proceedings of the National Academy of Sciences of the United States of America (1978)
Stable propagation of cosmid sized human DNA inserts in an F factor based vector.
Ung-Jin Kim;Hiroaki Shizuya;Pieter J. de Jong;Bruce Birren.
Nucleic Acids Research (1992)
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