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Martha H. Stipanuk

Martha H. Stipanuk

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
11118
World Ranking
14445
National Ranking
6078

Overview

Martha H. Stipanuk is affiliated with Cornell University in the United States and focuses their research on biochemistry, genetics, molecular biology, and medicine. Their scientific work spans various subfields including rheumatology, biochemistry, molecular biology, clinical biochemistry, and inorganic chemistry.

Their research addresses several main topics such as folate and B vitamins, sulfur compounds in biology, metabolism and genetic disorders, metal-catalyzed oxygenation mechanisms, heme oxygenase-1 and carbon monoxide, microbial metabolism and enzyme function, and aspects of birth, development, and health.

Among recent scholarly contributions, Stipanuk has published the following papers:

  • Metabolism of Sulfur-Containing Amino Acids: How the Body Copes with Excess Methionine, Cysteine, and Sulfide (2020, Journal of Nutrition)
  • Spectroscopic Investigation of Cysteamine Dioxygenase (2020, Biochemistry)
  • High Cysteine Diet Reduces Insulin Resistance in SHR-CRP Rats (2021, Physiological Research)

Published work appears across several venues, reflecting the interdisciplinary nature of their research, including:

  • Journal of Nutrition
  • Biochemistry
  • Physiological Research

Frequent collaborators in their research include Rebeca L. Fernandez, Stephanie Dillon, Brian G. Fox, Thomas C. Brunold, and Jakub Krijt. This network represents a range of expertise contributing to advancing studies in related biochemical fields.

Best Publications

  • SULFUR AMINO ACID METABOLISM: Pathways for Production and Removal of Homocysteine and Cysteine

    Martha H. Stipanuk

  • Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat.

    M H Stipanuk;P W Beck

  • Mammalian Cysteine Metabolism: New Insights into Regulation of Cysteine Metabolism

    Martha H. Stipanuk;John E. Dominy;Jeong-In Lee;Relicardo M. Coloso

  • Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur

    Martha H. Stipanuk;Iori Ueki

  • Metabolism of Sulfur-Containing Amino Acids

    Martha H. Stipanuk

  • Biochemical and Physiological Aspects of Human Nutrition

    Martha H. Stipanuk

  • Leucine and Protein Synthesis: mTOR and Beyond

    Martha H. Stipanuk

  • Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels.

    MH Stipanuk;I Ueki;Jr Je Dominy;CR Simmons

  • Crystal Structure of Mammalian Cysteine Dioxygenase: A NOVEL MONONUCLEAR IRON CENTER FOR CYSTEINE THIOL OXIDATION.

    Chad R. Simmons;Qun Liu;Qingqiu Huang;Quan Hao

  • Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes.

    Martha H. Stipanuk;Relicardo M. Coloso;Rolando A. G. Garcia;Mark F. Banks

  • Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase.

    John E. Dominy;Chad R. Simmons;Lawrence L. Hirschberger;Jesse Hwang

  • Role of the liver in regulation of body cysteine and taurine levels: A brief review

    Martha H. Stipanuk

  • Enzymes and Metabolites of Cysteine Metabolism in Nonhepatic Tissues of Rats Show Little Response to Changes in Dietary Protein or Sulfur Amino Acid Levels

    Martha H. Stipanuk;Monica Londono;Jeong-In Lee;Mindy Hu

  • Evidence for a rate-limiting role of cysteinesulfinate decarboxylase activity in taurine biosynthesis in vivo

    J de la Rosa;M H Stipanuk

  • Serum micronutrient concentrations and decline in physical function among older persons.

    Benedetta Bartali;Edward A. Frongillo;Jack M. Guralnik;Martha H. Stipanuk

  • Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide.

    Iori Ueki;Heather B. Roman;Alessandro Valli;Krista Fieselmann

  • Synthesis of amino acid cofactor in cysteine dioxygenase is regulated by substrate and represents a novel post-translational regulation of activity.

    John E. Dominy;Jesse Hwang;Stephanie Guo;Lawrence L. Hirschberger

  • Thiol dioxygenases: unique families of cupin proteins

    Martha H. Stipanuk;Chad R. Simmons;Chad R. Simmons;P. Andrew Karplus;John E. Dominy;John E. Dominy

  • New Roles for Cysteine and Transsulfuration Enzymes: Production of H2S, a Neuromodulator and Smooth Muscle Relaxant

    John E. Dominy;Martha H. Stipanuk

  • Identification and Characterization of Bacterial Cysteine Dioxygenases: a New Route of Cysteine Degradation for Eubacteria

    John E. Dominy;Chad R. Simmons;P. Andrew Karplus;Amy M. Gehring

Frequent Co-Authors

P. Andrew Karplus
P. Andrew Karplus Oregon State University
Edward A. Frongillo
Edward A. Frongillo University of South Carolina
Luigi Ferrucci
Luigi Ferrucci National Institutes of Health
Jack M. Guralnik
Jack M. Guralnik University of Maryland, Baltimore
Jason W. Locasale
Jason W. Locasale Duke University
Quan Hao
Quan Hao University of Hong Kong
Tadhg P. Begley
Tadhg P. Begley Texas A&M University
Stefania Bandinelli
Stefania Bandinelli University of Michigan–Ann Arbor
Nicholas O. Davidson
Nicholas O. Davidson Washington University in St. Louis
Vadim N. Gladyshev
Vadim N. Gladyshev Brigham and Women's Hospital

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