D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 63 Citations 9,699 151 World Ranking 6814 National Ranking 3158

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Mario Ascoli spends much of his time researching Receptor, Endocrinology, Gonadotropin, Leydig cell and Cell culture. His Receptor research includes themes of Hormone, Luteinizing hormone, Transfection and Tumor cells. Mario Ascoli combines subjects such as Ovulation and Pregnancy with his study of Luteinizing hormone.

His Endocrinology research incorporates elements of Epidermal growth factor and Inositol phosphate. His work on luteinizing hormone/choriogonadotropin receptor as part of general Gonadotropin research is often related to Touch sensation, thus linking different fields of science. His study looks at the relationship between Leydig cell and topics such as Protein kinase A, which overlap with Forskolin and Second messenger system.

His most cited work include:

  • The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective (629 citations)
  • Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses* (539 citations)
  • The Lutropin/Choriogonadotropin Receptor… 4 Years Later* (377 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Endocrinology, Receptor, Cell biology, Leydig cell and Gonadotropin. His Endocrinology research incorporates themes from Cell culture and Epidermal growth factor. His work carried out in the field of Receptor brings together such families of science as Molecular biology, Transfection and Phosphorylation.

Mario Ascoli studied Cell biology and Mutant that intersect with G protein-coupled receptor. His work in Leydig cell addresses issues such as Protein kinase A, which are connected to fields such as Protein kinase C. His biological study spans a wide range of topics, including Complementary DNA, Messenger RNA and Leydig Cell Tumor.

He most often published in these fields:

  • Endocrinology (55.92%)
  • Receptor (49.34%)
  • Cell biology (24.34%)

What were the highlights of his more recent work (between 2004-2019)?

  • Endocrinology (55.92%)
  • luteinizing hormone/choriogonadotropin receptor (13.82%)
  • Receptor (49.34%)

In recent papers he was focusing on the following fields of study:

Mario Ascoli focuses on Endocrinology, luteinizing hormone/choriogonadotropin receptor, Receptor, Phosphorylation and Cell biology. While the research belongs to areas of Endocrinology, Mario Ascoli spends his time largely on the problem of Gq alpha subunit, intersecting his research to questions surrounding Phospholipase C and Corpus luteum. The study incorporates disciplines such as Epidermal growth factor, Signal transduction, Inositol phosphate and Granulosa cell in addition to luteinizing hormone/choriogonadotropin receptor.

Mario Ascoli has included themes like Mutation and Mutant in his Receptor study. Mario Ascoli has researched Phosphorylation in several fields, including Molecular biology, Downregulation and upregulation and Epidermal growth factor receptor. His Cell biology study which covers Transfection that intersects with Growth factor, Fusion protein, Ovarian follicle, Transport protein and Cell.

Between 2004 and 2019, his most popular works were:

  • The differential effects of the gonadotropin receptors on aromatase expression in primary cultures of immature rat granulosa cells are highly dependent on the density of receptors expressed and the activation of the inositol phosphate cascade (72 citations)
  • Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade. (71 citations)
  • Ovulation Involves the Luteinizing Hormone-Dependent Activation of Gq/11 in Granulosa Cells (55 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

The scientist’s investigation covers issues in Endocrinology, luteinizing hormone/choriogonadotropin receptor, Luteinizing hormone, Signal transduction and Gonadotropin. Mario Ascoli studies Endocrinology, focusing on Leydig cell in particular. His research ties Receptor and luteinizing hormone/choriogonadotropin receptor together.

His research integrates issues of Steroid biosynthesis, Kinase and Gonadotropic cell in his study of Receptor. His Luteinizing hormone research integrates issues from Ovulation, Protein kinase B, Cell culture and Follicular phase. His work in Signal transduction addresses subjects such as Inositol phosphate, which are connected to disciplines such as Follicle-stimulating hormone receptor and Multiplicity of infection.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective

Mario Ascoli;Francesca Fanelli;Deborah L. Segaloff.
Endocrine Reviews (2002)

831 Citations

Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses*

Mario Ascoli.
Endocrinology (1981)

672 Citations

The Lutropin/Choriogonadotropin Receptor… 4 Years Later*

Deborah L. Segaloff;Mario Ascoli.
Endocrine Reviews (1993)

487 Citations

Degradation of receptor-bound human choriogonadotropin by murine Leydig tumor cells.

M Ascoli;D Puett.
Journal of Biological Chemistry (1978)

219 Citations

Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells

Mario Ascoli;David Puett.
Proceedings of the National Academy of Sciences of the United States of America (1978)

186 Citations

Internalization and degradation of receptor-bound human choriogonadotropin in Leydig tumor cells. Fate of the hormone subunits.

M Ascoli.
Journal of Biological Chemistry (1982)

172 Citations

Regulation of gonadotropin receptors and gonadotropin responses in a clonal strain of Leydig tumor cells by epidermal growth factor.

M Ascoli.
Journal of Biological Chemistry (1981)

170 Citations

The Lutropin/Choriogonadotropin Receptor-Induced Phosphorylation of the Extracellular Signal-Regulated Kinases in Leydig Cells Is Mediated by a Protein Kinase A-Dependent Activation of Ras

Takashi Hirakawa;Mario Ascoli.
Molecular Endocrinology (2003)

121 Citations

GIPC binds to the human lutropin receptor (hLHR) through an unusual PDZ domain binding motif, and it regulates the sorting of the internalized human choriogonadotropin and the density of cell surface hLHR.

Takashi Hirakawa;Colette Galet;Mikiko Kishi;Mario Ascoli.
Journal of Biological Chemistry (2003)

119 Citations

The inositol phosphate/diacylglycerol pathway in MA-10 Leydig tumor cells. Activation by arginine vasopressin and lack of effect of epidermal growth factor and human choriogonadotropin.

M Ascoli;O P Pignataro;D L Segaloff.
Journal of Biological Chemistry (1989)

117 Citations

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