Mario Ascoli

Overview

Best Publications

• The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective

  Mario Ascoli;Francesca Fanelli;Deborah L. Segaloff

  902
  Citations

• Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses*

  Mario Ascoli

  695
  Citations

• The Lutropin/Choriogonadotropin Receptor… 4 Years Later*

  Deborah L. Segaloff;Mario Ascoli

  519
  Citations

• Degradation of receptor-bound human choriogonadotropin by murine Leydig tumor cells.

  M Ascoli;D Puett

  220
  Citations

• Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells

  Mario Ascoli;David Puett

  186
  Citations

• Regulation of gonadotropin receptors and gonadotropin responses in a clonal strain of Leydig tumor cells by epidermal growth factor.

  M Ascoli

  178
  Citations

• Internalization and degradation of receptor-bound human choriogonadotropin in Leydig tumor cells. Fate of the hormone subunits.

  M Ascoli

  176
  Citations

• Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.

  Koji Shiraishi;Mario Ascoli

  130
  Citations

• The Lutropin/Choriogonadotropin Receptor-Induced Phosphorylation of the Extracellular Signal-Regulated Kinases in Leydig Cells Is Mediated by a Protein Kinase A-Dependent Activation of Ras

  Takashi Hirakawa;Mario Ascoli

  127
  Citations

• Lutropin/choriogonadotropin down-regulates its receptor by both receptor-mediated endocytosis and a cAMP-dependent reduction in receptor mRNA.

  Haiyun Wang;D. L. Segaloff;M. Ascoli

  125
  Citations

• GIPC binds to the human lutropin receptor (hLHR) through an unusual PDZ domain binding motif, and it regulates the sorting of the internalized human choriogonadotropin and the density of cell surface hLHR.

  Takashi Hirakawa;Colette Galet;Mikiko Kishi;Mario Ascoli

  124
  Citations

• Inhibition of choriogonadotropin-activated steroidogenesis in cultured Leydig tumor cells by the Rp diastereoisomer of adenosine 3',5'-cyclic phosphorothioate.

  M.E. Pereira;D.L. Segaloff;M. Ascoli;F. Eckstein

  124
  Citations

• Studies on the source of cholesterol used for steroid biosynthesis in cultured Leydig tumor cells.

  D A Freeman;M Ascoli

  120
  Citations

• On the Structure of the Luteinizing Hormone/Chorionic Gonadotropin Receptor*

  Mario Ascoli;Deborah L. Segaloff

  119
  Citations

• The inositol phosphate/diacylglycerol pathway in MA-10 Leydig tumor cells. Activation by arginine vasopressin and lack of effect of epidermal growth factor and human choriogonadotropin.

  M Ascoli;O P Pignataro;D L Segaloff

  119
  Citations

• The differential effects of the gonadotropin receptors on aromatase expression in primary cultures of immature rat granulosa cells are highly dependent on the density of receptors expressed and the activation of the inositol phosphate cascade

  Francesc Xavier Donadeu;Mario Ascoli

  118
  Citations

• Inhibition of the degradation of receptor-bound human choriogonadotropin by lysosomotropic agents, protease inhibitors, and metabolic inhibitors.

  M Ascoli;D Puett

  116
  Citations

• On the mechanisms involved in the regulation of the cell-surface receptors for human choriogonadotropin and mouse epidermal growth factor in cultured Leydig tumor cells.

  C E Lloyd;M Ascoli

  111
  Citations

• Follitropin (Fsh) And A Phorbol Ester Stimulate The Phosphorylation Of The Fsh Receptor In Intact-Cells

  J Quintana;R W Hipkin;J Sánchez-Yagüe;M Ascoli

  108
  Citations

• Endocrine, Paracrine, and Autocrine Signaling Pathways That Regulate Ovulation.

  JoAnne S. Richards;Mario Ascoli

  103
  Citations