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Marian L. Hamshere

Marian L. Hamshere

D-Index & Metrics

Genetics

D-Index
79
Citations
62132
World Ranking
1602
National Ranking
206

Overview

Marian L. Hamshere is affiliated with Cardiff University in the United Kingdom and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research portfolio primarily addresses various aspects of genetics, with a focus on genetic associations and epidemiology.

Their work covers several subfields including Genetics, Molecular Biology, Statistics and Probability, Epidemiology, and Endocrine and Autonomic Systems.

Key topics explored in their research include:

  • Genetic Associations and Epidemiology
  • Genomic Variations and Chromosomal Abnormalities
  • Receptor Mechanisms and Signaling
  • Genetics and Neurodevelopmental Disorders
  • Genomics and Rare Diseases
  • Advanced Causal Inference Techniques
  • Liver Disease Diagnosis and Treatment

Recent publications by Marian L. Hamshere include:

  • "A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts," 2021, published in Biological Psychiatry
  • "Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders," 2021, published in Biological Psychiatry
  • "Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions," 2023, published in Cell Genomics
  • "Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders," 2020, published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Distinct genetic liability profiles define clinically relevant patient strata across common diseases," 2024, published in Nature Communications

The scientist frequently collaborates with several co-authors across their publications, including:

  • Srdjan Djurovic
  • Franziska Degenhardt
  • Ingrid Agartz
  • Tim B. Bigdeli
  • Nick Craddock

Marian L. Hamshere's works have been published predominantly in the journals Biological Psychiatry and bioRxiv (Cold Spring Harbor Laboratory), with multiple articles appearing in both. Other venues include UNC Libraries, Cell Genomics, and Nature Communications.

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

    D Harold;R Abraham;P Hollingworth;R Sims

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

    Antonio F. Pardiñas;Peter Holmans;Andrew J. Pocklington;Valentina Escott-Price

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

    Manuel A R Ferreira;Michael C O'Donovan;Yan A Meng;Ian R Jones

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Identification of loci associated with schizophrenia by genome-wide association and follow-up

    Michael C. O'Donovan;Nicholas Craddock;Nadine Norton;Hywel Williams

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

    Lesley Jones;Peter A. Holmans;Marian L. Hamshere;Denise Harold

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimertextquotesingles disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

Frequent Co-Authors

Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Michael John Owen
Michael John Owen Cardiff University
Peter Holmans
Peter Holmans Cardiff University
Nicholas John Craddock
Nicholas John Craddock Cardiff University
Stephan Ripke
Stephan Ripke Massachusetts General Hospital
George Kirov
George Kirov Cardiff University
Sven Cichon
Sven Cichon University of Basel
Dan Rujescu
Dan Rujescu Medical University of Vienna
Thomas G. Schulze
Thomas G. Schulze Ludwig-Maximilians-Universität München
Thomas Werge
Thomas Werge University of Copenhagen

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