Patrick Pale focuses on Catalysis, Organic chemistry, Heterogeneous catalysis, Click chemistry and Medicinal chemistry. He combines subjects such as Methanol and Silver salts with his study of Catalysis. His Organic chemistry and Copper, Regioselectivity, Molecule, Cascade reaction and Lactone investigations all form part of his Organic chemistry research activities.
He focuses mostly in the field of Heterogeneous catalysis, narrowing it down to matters related to Solvent and, in some cases, Halide, Triazole and Sodium azide. His Click chemistry research is multidisciplinary, incorporating elements of Cycloaddition, Green chemistry and Organic synthesis. His Medicinal chemistry study incorporates themes from Nucleophilic addition, Alcohol, Furan, Enol and Oxophilicity.
His scientific interests lie mostly in Catalysis, Organic chemistry, Medicinal chemistry, Combinatorial chemistry and Zeolite. His research in Catalysis intersects with topics in Aryl, Polymer chemistry and Copper. His Cycloaddition, Regioselectivity, Stereoselectivity, Molecule and Total synthesis investigations are all subjects of Organic chemistry research.
He works mostly in the field of Cycloaddition, limiting it down to topics relating to Click chemistry and, in certain cases, Organic synthesis, as a part of the same area of interest. He interconnects Ion, Protonation, Reaction conditions, Stereochemistry and Sulfonyl in the investigation of issues within Medicinal chemistry. His work on Nucleophile expands to the thematically related Combinatorial chemistry.
His primary scientific interests are in Catalysis, Medicinal chemistry, Crystal structure, Crystallography and Organic chemistry. The various areas that Patrick Pale examines in his Catalysis study include Combinatorial chemistry and Nucleophilic substitution. His Combinatorial chemistry research integrates issues from Heterocycle synthesis, Bicyclic molecule, Azepine and Homogeneous catalysis.
His Medicinal chemistry research incorporates elements of Palladium, Cycloisomerization, Carbene, Aryl and Sulfonyl. His Zeolite research includes themes of Heterogeneous catalysis, Neopentane and Chemical engineering. His biological study spans a wide range of topics, including Docking, Rational design, Ligand, Polymer chemistry and Copper.
Patrick Pale spends much of his time researching Catalysis, Organic chemistry, Combinatorial chemistry, Zeolite and Medicinal chemistry. A large part of his Catalysis studies is devoted to Heterocycle synthesis. His Organic chemistry study focuses mostly on Reaction conditions and Halogenation.
His Combinatorial chemistry research is multidisciplinary, incorporating perspectives in Heterogeneous catalysis, Nucleophile and Homogeneous catalysis. His work on ZSM-5 as part of general Zeolite research is frequently linked to High-resolution transmission electron microscopy, bridging the gap between disciplines. His studies deal with areas such as Ligand and Carbene as well as Medicinal chemistry.
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Ag-mediated reactions: coupling and heterocyclization reactions.
Jean-Marc Weibel;Aurélien Blanc;Patrick Pale.
Chemical Reviews (2008)
Click chemistry in CuI-zeolites: the Huisgen [3 + 2]-cycloaddition.
Stefan Chassaing;Mayilvasagam Kumarraja;Abdelkarim Sani Souna Sido;Patrick Pale.
Organic Letters (2007)
"Click chemistry" in zeolites: copper(I) zeolites as new heterogeneous and ligand-free catalysts for the Huisgen [3+2] cycloaddition.
Stefan Chassaing;Abdelkarim Sani Souna Sido;Aurélien Alix;Mayilvasagam Kumarraja.
Chemistry: A European Journal (2008)
The organic chemistry of silver acetylides
Ulla Halbes-Letinois;Jean-Marc Weibel;Patrick Pale.
Chemical Society Reviews (2007)
Versatile and Expeditious Synthesis of Aurones via AuI-Catalyzed Cyclization
Hassina Harkat;Aurélien Blanc;Jean-Marc Weibel;Patrick Pale.
Journal of Organic Chemistry (2008)
A mild access to γ- or δ-alkylidene lactones through gold catalysis
Hassina Harkat;Jean-Marc Weibel;Patrick Pale.
Tetrahedron Letters (2006)
Copper(I) zeolites as heterogeneous and ligand-free catalysts: [3+2] cycloaddition of azomethine imines.
Murielle Keller;Abdelkarim Sani Souna Sido;Patrick Pale;Jean Sommer.
Chemistry: A European Journal (2009)
When CuAAC 'Click Chemistry' goes heterogeneous
S. Chassaing;V. Bénéteau;P. Pale.
Catalysis Science & Technology (2016)
Mechanistic studies and improvement of coinage metal-catalyzed transformation of alkynyloxiranes to furans: an alcohol addition-cyclization-elimination cascade.
Aurélien Blanc;Katharina Tenbrink;Jean-Marc Weibel;Patrick Pale.
Journal of Organic Chemistry (2009)
An improved procedure for aldehyde-to-alkyne homologation via 1,1-dibromoalkenes; synthesis of 1-bromoalkynes
D. Grandjean;P. Pale;J. Chuche.
Tetrahedron Letters (1994)
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