Manu Shankar‐Hari

Best Publications

• The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

  Mervyn Singer;Clifford S. Deutschman;Christopher Warren Seymour;Manu Shankar-Hari

  29560
  Citations

• Genetic mechanisms of critical illness in Covid-19.

  E. Pairo-Castineira;E. Pairo-Castineira;S. Clohisey;L. Klaric;A. D. Bretherick

  1445
  Citations

• Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans.

  Jeffrey Seow;Carl Graham;Blair Merrick;Sam Acors

  1214
  Citations

• Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection

  Unknown

  1020
  Citations

• A dynamic COVID-19 immune signature includes associations with poor prognosis.

  Adam G. Laing;Anna Lorenc;Irene del Molino del Barrio;Irene del Molino del Barrio;Abhishek Das;Abhishek Das

  962
  Citations

• The immunology of sepsis

  Tom van der Poll;Manu Shankar-Hari;Manu Shankar-Hari;W. Joost Wiersinga

  887
  Citations

• The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity.

  Marcin F. Osuchowski;Martin S. Winkler;Tomasz Skirecki;Sara Cajander

  541
  Citations

• A guide to immunotherapy for COVID-19

  Unknown

  531
  Citations

• Whole-genome sequencing reveals host factors underlying critical COVID-19

  Unknown

  514
  Citations

• Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection.

  Michael J. Carter;Michael J. Carter;Matthew Fish;Matthew Fish;Aislinn Jennings;Aislinn Jennings;Katie J. Doores

  429
  Citations

• Current gaps in sepsis immunology: new opportunities for translational research.

  Ignacio Rubio;Marcin F Osuchowski;Manu Shankar-Hari;Manu Shankar-Hari;Tomasz Skirecki

  364
  Citations

• Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex

  Unknown

  300
  Citations

• Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study

  Unknown

  168
  Citations

• SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care.

  Clemens Gutmann;Kaloyan Takov;Sean A Burnap;Bhawana Singh

  160
  Citations

• Sepsis Subclasses: A Framework for Development and Interpretation.

  Kimberley M DeMerle;Derek C Angus;J Kenneth Baillie;Emily Brant

  159
  Citations

• Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study)

  Tobias Welte;R. Phillip Dellinger;Henning Ebelt;Miguel Ferrer

  151
  Citations

• Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant.

  Carl Graham;Jeffrey Seow;Isabella Huettner;Hataf Khan

  148
  Citations

• Bench-to-bedside review: Immunoglobulin therapy for sepsis - biological plausibility from a critical care perspective

  Manu Shankar-Hari;Manu Shankar-Hari;Jo Spencer;William A Sewell;Kathryn M Rowan

  143
  Citations

• Cell-surface signatures of immune dysfunction risk-stratify critically ill patients: INFECT study

  Andrew Conway Morris;Andrew Conway Morris;Deepankar Datta;Manu Shankar-Hari;Jacqueline Stephen

  130
  Citations

• Activation-Associated Accelerated Apoptosis of Memory B Cells in Critically Ill Patients With Sepsis.

  Manu Shankar-Hari;David Fear;Paul Lavender;Tracey Mare

  123
  Citations