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Biology and Biochemistry

D-Index
82
Citations
19389
World Ranking
3769
National Ranking
1866

Overview

Kenneth O. Lloyd is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields such as Neurology, Oncology, Immunology, Immunology and Allergy, and Radiology, Nuclear Medicine and Imaging.

The scientist's research topics notably include:

  • Neuroblastoma Research and Treatments
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Cell Adhesion Molecules Research
  • Monoclonal and Polyclonal Antibodies Research
  • Biochemical and Structural Characterization
  • Microtubule and mitosis dynamics

Lloyd's recent papers illustrate active involvement in oncology and immunology-related studies. The recent publications are:

  • CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness, 2024, Science Advances
  • Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits, 2024, mAbs
  • Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits, 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • Abstract 5498: Plinabulin, a novel tubulin targeting agent, collapses the proinvasion tumor microtube network in primary and recurrent patient derived glioblastoma cell lines to inhibit neurosphere invasion and survival, 2022, Cancer Research
  • Tregcells drive MYCN-mediated immunosuppression and tumor aggressiveness in high-risk neuroblastoma, 2022, bioRxiv (Cold Spring Harbor Laboratory)

Collaborative efforts are evident through frequent co-authors including:

  • Rob Meijers
  • Xiaodan Qin
  • Andrew Lam
  • Satyaki Sengupta
  • Tao Zuo

The scientist has published consistently in several venues, with the most frequent being:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • mAbs
  • Molecular Cancer Therapeutics

Their work touches on topics that relate to tumor biology, immune suppression mechanisms, antibody discovery, and therapeutic strategies involving microtubule dynamics and cell adhesion. Specific areas such as MYCN-mediated tumor aggressiveness and immune cell interactions are recurrent themes in their recent output.

Best Publications

  • Molecular Cloning of the CA125 Ovarian Cancer Antigen: IDENTIFICATION AS A NEW MUCIN, MUC16

    Beatrice W.T. Yin;Kenneth O. Lloyd

  • The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

    Rogier W. Sanders;Miro Venturi;Linnea Schiffner;Roopa Kalyanaraman

  • Cell surface antigens of human malignant melanoma: definition of six antigenic systems with mouse monoclonal antibodies

    Wolfgang G. Dippold;Kenneth O. Lloyd;Lucy T. C. Li;Hisami Ikeda

  • GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody.

    Clifford S. Pukel;Kenneth O. Lloyd;Luiz R. Travassos;Wolfgang G. Dippold

  • Comparison of O-Linked Carbohydrate Chains in MUC-1 Mucin from Normal Breast Epithelial Cell Lines and Breast Carcinoma Cell Lines: DEMONSTRATION OF SIMPLER AND FEWER GLYCAN CHAINS IN TUMOR CELLS

    Kenneth O. Lloyd;Joy Burchell;Valery Kudryashov;Beatrice W.T. Yin

  • Selection of tumor antigens as targets for immune attack using immunohistochemistry: I. Focus on gangliosides

    Shengle Zhang;Carlos Cordon-Cardo;Helen S. Zhang;Victor E. Reuter

  • Selection of tumor antigens as targets for immune attack using immunohistochemistry: II. Blood group-related antigens

    Shengle Zhang;Helen S. Zhang;Carlos Cordon-Cardo;Victor E. Reuter

  • Cell surface antigens of human bladder cancer defined by mouse monoclonal antibodies

    Yves Fradet;Carlos Cordon-Cardo;Timothy Thomson;Mary E. Daly

  • Carbohydrate vaccines in cancer: Immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man

    S. F. Slovin;G. Ragupathi;S. Adluri;G. Ungers

  • Expression of Lewisa, Lewisb, X, and Y blood group antigens in human colonic tumors and normal tissue and in human tumor-derived cell lines.

    Junichi Sakamoto;Koichi Furukawa;Carlos Cordon-Cardo;Beatrice W. T. Yin

  • Isolation of GD3 synthase gene by expression cloning of GM3 alpha-2,8-sialyltransferase cDNA using anti-GD2 monoclonal antibody

    M Haraguchi;S Yamashiro;A Yamamoto;K Furukawa

  • Expression of Lewisa, Lewisb, Lewisx, Lewisy, Sialyl-Lewisa, and Sialyl-Lewisx Blood Group Antigens in Human Gastric Carcinoma and in Normal Gastric Tissue

    Junichi Sakamoto;Tadashi Watanabe;Takahiko Tokumaru;Hiroshi Takagi

  • Immunochemical studies on blood groups. XLI. Proposed structures for the carbohydrate portions of blood group A, B, H, Lewis-a, and Lewis-b substances.

    Kenneth O. Lloyd;Elvin A. Kabat

  • Heterogeneity in surface antigen and glycoprotein expression of cell lines derived from different melanoma metastases of the same patient. Implications for the study of tumor antigens.

    A P Albino;K O Lloyd;A N Houghton;H F Oettgen

  • Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides.

    Y Nagata;S Yamashiro;J Yodoi;K O Lloyd

  • Immunochemical Studies on Blood Groups. XXXIV. Structures of Some Oligosaccharides Produced by Alkaline Degradation of Blood Group A, B, and H Substances*

    Kenneth O. Lloyd;Elvin A. Kabat;Espriela J. Layug;Flavio Gruezo

  • Philip Levine award lecture. Blood group antigens as markers for normal differentiation and malignant change in human tissues.

    Kenneth O. Lloyd

  • Ganglioside expression on human malignant melanoma assessed by quantitative immune thin-layer chromatography.

    Wm. Bradley Hamilton;Friedhelm Helling;Kenneth O. Lloyd;Philip O. Livingston

  • Cell surface antigens of human renal cancer defined by mouse monoclonal antibodies: identification of tissue-specific kidney glycoproteins

    Ryuzo Ueda;Shun-Ichiro Ogata;Donna M. Morrissey;Connie L. Finstad

  • Isolation, characterization, and partial structure of peptido galactomannans from the yeast form of Cladosporium werneckii.

    Kenneth O. Lloyd

Frequent Co-Authors

Lloyd J. Old
Lloyd J. Old Ludwig Cancer Research
Herbert F. Oettgen
Herbert F. Oettgen Memorial Sloan Kettering Cancer Center
Philip O. Livingston
Philip O. Livingston Memorial Sloan Kettering Cancer Center
Stephen C. Rubin
Stephen C. Rubin University of Pennsylvania
William J. Hoskins
William J. Hoskins Memorial Sloan Kettering Cancer Center
Carlos Cordon-Cardo
Carlos Cordon-Cardo Icahn School of Medicine at Mount Sinai
Koichi Furukawa
Koichi Furukawa Chubu University
Hiroshi Shiku
Hiroshi Shiku Mie University
Francisco X. Real
Francisco X. Real Pompeu Fabra University
Victor E. Reuter
Victor E. Reuter Memorial Sloan Kettering Cancer Center

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