Karen J. Shaw

Best Publications

• Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes

  Unknown

  1059
  Citations

• Antibiotic Susceptibility Profiles of <i>Escherichia coli</i> Strains Lacking Multidrug Efflux Pump Genes

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  493
  Citations

• The oxazolidinones: past, present, and future

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  251
  Citations

• The most frequent aminoglycoside resistance mechanisms--changes with time and geographic area: a reflection of aminoglycoside usage patterns? Aminoglycoside Resistance Study Groups.

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  245
  Citations

• Antibiotic Susceptibility of Multiply Resistant Pseudomonas aeruginosa Isolated from Patients with Cystic Fibrosis, Including Candidates for Transplantation

  Lisa Saiman;Farrah Mehar;Wei Wei Niu;Harold C. Neu

  230
  Citations

• Novel Ribosomal Mutations in <i>Staphylococcus aureus</i> Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)

  Unknown

  202
  Citations

• Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents.

  Karen Joy Shaw;Nancy Miller;Xuejun Liu;Dmitri Lerner

  198
  Citations

• In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains

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  183
  Citations

• Fosmanogepix: A Review of the First-in-Class Broad Spectrum Agent for the Treatment of Invasive Fungal Infections.

  Karen Joy Shaw;Ashraf S. Ibrahim

  181
  Citations

• In Vitro and In Vivo Evaluation of the Antifungal Activity of APX001A/APX001 against Candida auris.

  Christopher L. Hager;Emily L. Larkin;Lisa Long;Fatima Zohra Abidi

  165
  Citations

• A novel gentamicin resistance gene in Enterococcus.

  Joseph W. Chow;Marcus J. Zervos;Stephen A. Lerner;Lee Ann Thal

  149
  Citations

• Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant <i>Staphylococcus aureus</i> Strains Possessing the <i>cfr</i> Methyltransferase Gene or Ribosomal Mutations

  Unknown

  146
  Citations

• ESCHERICHIA COLI K-12 AUXOTROPHS INDUCED BY INSERTION OF THE TRANSPOSABLE ELEMENT Tn5

  Unknown

  145
  Citations

• Detection of the high-level aminoglycoside resistance gene aph(2")-Ib in Enterococcus faecium.

  Susan J. Kao;Il You;Don B. Clewell;Susan M. Donabedian

  140
  Citations

• In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus.

  Karen Joy Shaw;Wiley A. Schell;Jonathan Covel;Gisele Duboc

  134
  Citations

• Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin

  Unknown

  133
  Citations

• Predictive value of blood eosinophils and exhaled nitric oxide in adults with mild asthma: a prespecified subgroup analysis of an open-label, parallel-group, randomised controlled trial.

  Ian D Pavord;Mark Holliday;Helen K Reddel;Irene Braithwaite

  116
  Citations

• Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity

  Unknown

  115
  Citations

• Characterization of the chromosomal aac(6')-Ic gene from Serratia marcescens

  Unknown

  111
  Citations

• Genomics and Antimicrobial Drug Discovery

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  106
  Citations