2026 Jeroen Hugenholtz: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	71	6702	6184	173	158	149	16839

Overview

Jeroen Hugenholtz is affiliated with the University of Groningen in the Netherlands. Their research activity spans biochemistry, genetics, molecular biology, and engineering, with particular focus on microbial metabolic engineering and bioproduction.

The main fields of study associated with their work include:

Biochemistry, Genetics and Molecular Biology
Engineering

Within these fields, the prominent subfields they contribute to are:

Molecular Biology
Biomedical Engineering
Biotechnology
Genetics
Materials Chemistry

The key research topics in their portfolio cover:

Microbial Metabolic Engineering and Bioproduction
Biofuel production and bioconversion
Enzyme Catalysis and Immobilization
Bacterial Genetics and Biotechnology
Enzyme Structure and Function
Transgenic Plants and Applications
Plant tissue culture and regeneration

Jeroen Hugenholtz has published extensively, with a number of recent papers, including:

Fermentation for the production of biobased chemicals in a circular economy: a perspective for the period 2022-2050 (2022) in Green Chemistry
Tailoring and optimizing fatty acid production by oleaginous yeasts through the systematic exploration of their physiological fitness (2022) in Microbial Cell Factories
Exploring the potential of Bacillus subtilis as cell factory for food ingredients and special chemicals (2023) in Microbial Cell Factories
Model-driven approach for the production of butyrate from CO2/H2 by a novel co-culture of C. autoethanogenum and C. beijerinckii (2022) in Frontiers in Microbiology
Sustainable Production of the Cyanophycin Biopolymer in Tobacco in the Greenhouse and Field (2022) in Frontiers in Bioengineering and Biotechnology

The frequent publication venues where their work appears include:

bioRxiv (Cold Spring Harbor Laboratory)
Microbial Cell Factories
Bioresource Technology
Frontiers in Bioengineering and Biotechnology
Research Square (Research Square)

Collaborations form a notable part of their research output. Frequent co-authors include:

María Suárez-Diez
Zeynep Efsun Duman-Özdamar
Vítor A. P. Martins dos Santos
Stanley Brul
Mattijs K. Julsing

Best Publications

Applications of the Bacteriocin, Nisin

J Delves-Broughton;P Blackburn;R J Evans;J Hugenholtz

1266
Citations
An overview of the functionality of exopolysaccharides produced by lactic acid bacteria.

Patricia Ruas-Madiedo;Jeroen Hugenholtz;Pieternela Zoon

928
Citations
Microbes from raw milk for fermented dairy products

Jan T.M Wouters;Eman H.E Ayad;Jeroen Hugenholtz;Gerrit Smit

752
Citations
Citrate metabolism in lactic acid bacteria

Jeroen Hugenholtz

501
Citations
Mannitol production by lactic acid bacteria: a review

H.W Wisselink;R.A Weusthuis;G Eggink;J Hugenholtz

454
Citations
Unraveling microbial interactions in food fermentations: from classical to genomics approaches.

Sander Sieuwerts;Frank A. M. de Bok;Jeroen Hugenholtz;Johan E. T. van Hylckama Vlieg

360
Citations
COFACTOR ENGINEERING : A NOVEL APPROACH TO METABOLIC ENGINEERING IN LACTOCOCCUS LACTIS BY CONTROLLED EXPRESSION OF NADH OXIDASE

F Lopez de Felipe;M Kleerebezem;W M de Vos;J Hugenholtz

297
Citations
Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis

Marcel H. N. Hoefnagel;Marjo J. C. Starrenburg;Dirk E. Martens;Jeroen Hugenholtz

296
Citations
Effects of Cultivation Conditions on Folate Production by Lactic Acid Bacteria

Wilbert Sybesma;Marjo Starrenburg;Linda Tijsseling;Marcel H. N. Hoefnagel

291
Citations
Physiological function of exopolysaccharides produced by Lactococcus lactis

Petronella J Looijesteijn;Lionel Trapet;Eric de Vries;Tjakko Abee

283
Citations
Riboflavin production in Lactococcus lactis: potential for in situ production of vitamin-enriched foods.

Catherine Burgess;Mary O'Connell-Motherway;Wilbert Sybesma;Jeroen Hugenholtz

258
Citations
Mode of Action of Nisin Z against Listeria monocytogenes Scott A Grown at High and Low Temperatures

Tjakko Abee;Frank M. Rombouts;Jeroen Hugenholtz;Gilles Guihard

255
Citations
Properties of nisin Z and distribution of its gene, nisZ, in Lactococcus lactis.

W. M. De Vos;J. W. M. Mulders;R. J. Siezen;J. Hugenholtz

251
Citations
Lactobacillus reuteri CRL1098 produces cobalamin.

María P. Taranto;José L. Vera;Jeroen Hugenholtz;Graciela F. De Valdez;Graciela F. De Valdez

249
Citations
Conversion of Lactococcus lactis from homolactic to homoalanine fermentation through metabolic engineering

Pascal Hols;M Kleerebezem;André Schanck;T. Ferain

247
Citations
Citrate Fermentation by Lactococcus and Leuconostoc spp

Marjo J. C. Starrenburg;Jeroen Hugenholtz

244
Citations
Increased production of folate by metabolic engineering of Lactococcus lactis.

Wilbert Sybesma;Marjo Starrenburg;Michiel Kleerebezem;Igor Mierau

241
Citations
Metabolic engineering of acetaldehyde production by Streptococcus thermophilus.

A. C. S. D. Chaves;M. Fernandez;A. L. S. Lerayer;I. Mierau

229
Citations
Metabolic pathway engineering in lactic acid bacteria.

Michiel Kleerebezem;Jeroen Hugenholtz

223
Citations
Properties of Nisin Z and Distribution of Its Gene, nisZ, in Lactococcus lactis

Willem M. de Vos;John W.M. Mulders;Roland J. Siezen;Jeroen Hugenholtz

9
Citations