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Genetics

D-Index
68
Citations
15858
World Ranking
2436
National Ranking
1096

Research.com Recognitions

  • 2013 - Fellow of the American Statistical Association (ASA)

Overview

Janet S. Sinsheimer is affiliated with the University of California, Los Angeles in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine, with a focus on Genetics, Molecular Biology, Neurology, Epidemiology, and Physiology.

The scientist's work addresses main topics including Genetic Associations and Epidemiology, Parkinson's Disease Mechanisms and Treatments, Genetic and phenotypic traits in livestock, Genetic Mapping and Diversity in Plants and Animals, Epigenetics and DNA Methylation, Single-cell and spatial transcriptomics, and Liver Disease Diagnosis and Treatment.

Research by Janet S. Sinsheimer has been published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Genome Medicine, Movement Disorders, PLoS ONE, and Bioinformatics.

Recent papers include:

  • "Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients" (2020), Science Advances
  • "Human liver single nucleus and single cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival" (2022), Genome Medicine
  • "Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease" (2023), EBioMedicine
  • "Untargeted serum metabolomics reveals novel metabolite associations and disruptions in amino acid and lipid metabolism in Parkinson's disease" (2023), Molecular Neurodegeneration
  • "Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes" (2022), Brain

Frequent co-authors working with Janet S. Sinsheimer include Kenneth Lange, Päivi Pajukanta, Hua Zhou, Cynthia Kusters, and Kimberly C. Paul.

In recognition of their contributions to the field, Janet S. Sinsheimer was named a Fellow of the American Statistical Association (ASA) in 2013.

Best Publications

  • Epigenetic Predictor of Age

    Sven Bocklandt;Wen Lin;Mary E. Sehl;Francisco J. Sánchez

  • Bayesian Selection of Continuous-Time Markov Chain Evolutionary Models

    Marc A. Suchard;Robert E. Weiss;Janet S. Sinsheimer

  • Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application

    Rita M. Cantor;Kenneth Lange;Janet S. Sinsheimer

  • Comparative Analysis of Proteome and Transcriptome Variation in Mouse

    Anatole Ghazalpour;Brian Bennett;Vladislav A. Petyuk;Luz Orozco

  • Normal/Independent Distributions and Their Applications in Robust Regression

    Kenneth Lange;Janet S. Sinsheimer

  • Familial combined hyperlipidemia is associated with upstream transcription factor 1 ( USF1 )

    Päivi Pajukanta;Heidi E Lilja;Janet S Sinsheimer;Rita M Cantor

  • Chromosome 1 loci in Finnish schizophrenia families

    Jesper Ekelund;Iiris Hovatta;Alex Parker;Tiina Paunio

  • A Genomewide Screen for Autism-Spectrum Disorders: Evidence for a Major Susceptibility Locus on Chromosome 3q25-27

    Mari Auranen;Raija Vanhala;Teppo Varilo;Kristin Ayers

  • Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts

    Laure Frésard;Craig Smail;Nicole M. Ferraro;Nicole A. Teran

  • Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs

    Bridgett Marie vonHoldt;Emily Shuldiner;Emily Shuldiner;Ilana Janowitz Koch;Rebecca Y. Kartzinel

  • MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.

    Julia Wang;Rami Al-Ouran;Yanhui Hu;Seon-Young Kim

  • In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects.

    Walter J. Lech;Greg Wang;Yan Li Yang;Ying Chee

  • GENETIC INFLUENCES IN END-STAGE OSTEOARTHRITIS: SIBLING RISKS OF HIP AND KNEE REPLACEMENT FOR IDIOPATHIC OSTEOARTHRITIS

    Jai Chitnavis;Janet S. Sinsheimer;Kim Clipsham;John Loughlin

  • Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease.

    Angelika D. Wahner;Janet S. Sinsheimer;Jeff. M. Bronstein;Beate Ritz

  • Association screening of common and rare genetic variants by penalized regression

    Hua Zhou;Mary E. Sehl;Janet S. Sinsheimer;Kenneth Lange

  • Osteoarthritis-Susceptibility Locus on Chromosome 11q, Detected by Linkage

    Kay Chapman;Zehra Mustafa;Zehra Mustafa;Catherine Irven;Andrew J. Carr

  • Diagnostic utility of transcriptome sequencing for rare Mendelian diseases

    Hane Lee;Alden Y. Huang;Lee-kai Wang;Amanda J. Yoon

  • Suggestive linkage of the parathyroid receptor type 1 to osteoporosis.

    E L Duncan;M A Brown;M A Brown;J Sinsheimer;J Bell

  • The Undiagnosed Diseases Network: Accelerating Discovery about Health and Disease

    Rachel B. Ramoni;Rachel B. Ramoni;John J. Mulvihill;David R. Adams;Patrick Allard

  • Hierarchical phylogenetic models for analyzing multipartite sequence data.

    Marc A Suchard;Christina M R Kitchen;Janet S Sinsheimer;Janet S Sinsheimer;Robert E Weiss

Frequent Co-Authors

Kenneth Lange
Kenneth Lange University of California, Los Angeles
Beate Ritz
Beate Ritz University of California, Los Angeles
Marc A. Suchard
Marc A. Suchard University of California, Los Angeles
Päivi Pajukanta
Päivi Pajukanta University of California, Los Angeles
Andrew Carr
Andrew Carr University of Oxford
Eric Vilain
Eric Vilain George Washington University
Ingrid A. Holm
Ingrid A. Holm Boston Children's Hospital
Hane Lee
Hane Lee University of California, Los Angeles
Michael F. Wangler
Michael F. Wangler Baylor College of Medicine
Jill A. Rosenfeld
Jill A. Rosenfeld Baylor College of Medicine

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