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Neuroscience

D-Index
57
Citations
9737
World Ranking
4401
National Ranking
83

Overview

Jan Kehr is affiliated with the Karolinska Institute in Sweden and actively contributes to research in biochemistry, genetics, molecular biology, medicine, and neuroscience. Their work spans multiple subfields including molecular biology, cell biology, physiology, cellular and molecular neuroscience, and neurology.

The scientist's research focuses on topics such as receptor mechanisms and signaling, cellular transport and secretion, lysosomal storage disorders research, neuroinflammation and neurodegeneration mechanisms, nicotinic acetylcholine receptors study, neuroscience of respiration and sleep, and liver disease diagnosis and treatment.

Jan Kehr has published in several scientific venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Science Advances
  • Brain Communications

Several recent papers illustrate the scientist's range of topics and collaborations:

  • Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging, 2021, Science Advances
  • Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents, 2023, Nature Communications
  • Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery, 2022, Nature Communications
  • Cholinergic regulation of vascular endothelial function by human ChAT + T cells, 2023, Proceedings of the National Academy of Sciences
  • Dopaminergic neuromodulation of prefrontal cortex activity requires the NMDA receptor coagonist d-serine, 2021, Proceedings of the National Academy of Sciences

Jan Kehr's research collaborations include multiple frequent co-authors such as:

  • Takashi Yoshitake
  • Staffan Schmidt
  • Shimako Yoshitake
  • Laura Tarnawski
  • Eric J. Kort

Best Publications

  • Characterization and MRI study of surfactant-coated superparamagnetic nanoparticles administered into the rat brain

    D. K. Kim;Y. Zhang;J. Kehr;T. Klason

  • The role of 5-HT(1A) receptors in learning and memory.

    Sven Ove Ögren;Therese M. Eriksson;Elin Elvander-Tottie;Claudio D’Addario

  • Starch-Coated Superparamagnetic Nanoparticles as MR Contrast Agents

    Do Kyung Kim;Maria Mikhaylova;Fu Hua Wang;Jan Kehr

  • High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio

    Jaime M. Ross;Johanna Öberg;Stefan Brené;Giuseppe Coppotelli

  • Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats

    J. Kehr;F. Ichinose;S. Yoshitake;M. Goiny

  • Superparamagnetic iron oxide nanoparticles for bio-medical applications

    D.K Kim;Y Zhang;W Voit;K.V Rao

  • From the Golgi–Cajal mapping to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: Wiring and volume transmission☆

    Kjell Fuxe;Annica Dahlström;Malin Höistad;Daniel Marcellino

  • A survey on quantitative microdialysis: theoretical models and practical implications.

    Jan Kehr

  • Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

    Banafsheh Kadkhodaei;Alexandra Alvarsson;Nicoletta Schintu;Daniel Ramsköld

  • Cholinergic regulation of vascular endothelial function by human ChAT+ T cells

    Unknown

  • In Vivo Microdialysis as a Technique to Monitor Drug Transport: Correlation of Extracellular Cocaine Levels and Dopamine Overflow in the Rat Brain

    Yasmin L. Hurd;Jan Kehr;Urban Ungerstedt

  • The Ginkgo biloba extract EGb 761® and its main constituent flavonoids and ginkgolides increase extracellular dopamine levels in the rat prefrontal cortex

    T Yoshitake;S Yoshitake;J Kehr

  • Fast HPLC Estimation of γ‐Aminobutyric Acid in Microdialysis Perfusates: Effect of Nipecotic and 3‐Mercaptopropionic Acids

    Jan Kehr;Urban Ungerstedt

  • Sox6 and Otx2 Control the Specification of Substantia Nigra and Ventral Tegmental Area Dopamine Neurons

    Lia Panman;Lia Panman;Maria Papathanou;Ariadna Laguna;Ariadna Laguna;Tony Oosterveen

  • Effects of ventral hippocampal galanin on spatial learning and on in vivo acetylcholine release in the rat

    Ogren So;Kehr J;Schött Pa

  • Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function

    Eric W. Lumsden;Timothy A. Troppoli;Scott J. Myers;Panos Zanos

  • Determination of serotonin, noradrenaline, dopamine and their metabolites in rat brain extracts and microdialysis samples by column liquid chromatography with fluorescence detection following derivatization with benzylamine and 1,2-diphenylethylenediamine.

    Takashi Yoshitake;Jan Kehr;Shimako Yoshitake;Kaoru Fujino

  • Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons

    Gillian O'Meara;Urania Coumis;Shuang Y. Ma;Jan Kehr

  • Derivatization chemistries for determination of serotonin, norepinephrine and dopamine in brain microdialysis samples by liquid chromatography with fluorescence detection.

    T. Yoshitake;T. Yoshitake;J. Kehr;K. Todoroki;H. Nohta

  • Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness.

    Tomas Hökfelt;Swapnali Barde;Zhi Qing David Xu;Zhi Qing David Xu;Eugenia Kuteeva

  • MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease

    D. Galter;K. Pernold;T. Yoshitake;E. Lindqvist

  • Intraseptal muscarinic ligands and galanin: influence on hippocampal acetylcholine and cognition.

    E Elvander;P.A Schött;J Sandin;B Bjelke

Frequent Co-Authors

Kjell Fuxe
Kjell Fuxe Karolinska Institute
Sven-Ove Ögren
Sven-Ove Ögren Karolinska Institute
Tomas Hökfelt
Tomas Hökfelt Karolinska Institute
Börje Bjelke
Börje Bjelke University of Oslo
Dag Aarsland
Dag Aarsland King's College London
Mamoun Muhammed
Mamoun Muhammed Royal Institute of Technology
Tamas Bartfai
Tamas Bartfai Stockholm University
Greg A. Gerhardt
Greg A. Gerhardt University of Kentucky
Kina Höglund
Kina Höglund Sahlgrenska University Hospital
Aleksander A. Mathé
Aleksander A. Mathé Karolinska University Hospital

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