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Hyun Soo Cho

Hyun Soo Cho

D-Index & Metrics

Biology and Biochemistry

D-Index
41
Citations
9384
World Ranking
19537
National Ranking
229

Overview

Hyun Soo Cho is affiliated with Yonsei University in South Korea and has made contributions primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research focuses extensively on Molecular Biology, Cancer Research, Surgery, Genetics, and Oncology, reflecting a multidisciplinary approach to biological and medical sciences.

Their scholarly output includes work on a range of topics related to molecular and cancer biology. Key topics of research include:

  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Helicobacter pylori-related gastroenterology studies
  • Cancer-related gene regulation
  • Cancer-related molecular mechanisms research
  • Histone Deacetylase Inhibitors Research
  • 3D Printing in Biomedical Research

Several coauthors frequently collaborate with Hyun Soo Cho, contributing to a network of research partnerships:

  • Mi-Young Son
  • Dae-Soo Kim
  • Cho-Rok Jung
  • Kunhyang Park
  • Tae-Su Han

Their research has been published in a variety of venues, with multiple works appearing in:

  • Journal of Microbiology and Biotechnology
  • Biochemical and Biophysical Research Communications
  • Research Square (Research Square)
  • Experimental & Molecular Medicine
  • Molecules and Cells

Some of the recent papers featuring their contributions include:

  • "Epigenetic Associations between lncRNA/circRNA and miRNA in Hepatocellular Carcinoma," 2020, published in Cancers
  • "Human gut-microbiome-derived propionate coordinates proteasomal degradation via HECTD2 upregulation to target EHMT2 in colorectal cancer," 2022, published in The ISME Journal
  • "Anticancer Effects of Gut Microbiota-Derived Short-Chain Fatty Acids in Cancers," 2023, published in Journal of Microbiology and Biotechnology
  • "The development of a functional human small intestinal epithelium model for drug absorption," 2021, published in Science Advances
  • "Low-dose interleukin-2 alleviates dextran sodium sulfate-induced colitis in mice by recovering intestinal integrity and inhibiting AKT-dependent pathways," 2020, published in Theranostics

Hyun Soo Cho's work encompasses a broad investigation of molecular mechanisms underpinning cancer and gastrointestinal health, with particular attention to the interaction of genetic and epigenetic factors, RNA behavior in cancer, and the role of microbiota-derived compounds in disease modulation.

Best Publications

  • Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

    Hyun Soo Cho;Karen Mason;Kasra X. Ramyar;Ann Marie Stanley

  • An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

    Antony W. Burgess;Hyun Soo Cho;Hyun Soo Cho;Charles Eigenbrot;Kathryn M. Ferguson

  • EGF Activates Its Receptor by Removing Interactions that Autoinhibit Ectodomain Dimerization

    Kathryn M. Ferguson;Mitchell B. Berger;Jeannine M. Mendrola;Hyun Soo Cho

  • Structure of the Extracellular Region of HER3 Reveals an Interdomain Tether

    Hyun Soo Cho;Daniel J. Leahy

  • Crystal Structure of RNA Helicase from Genotype 1b Hepatitis C Virus A FEASIBLE MECHANISM OF UNWINDING DUPLEX RNA

    Hyun Soo Cho;Nam Chul Ha;Lin Woo Kang;Kyung Min Chung

  • Crystal structure of a maltogenic amylase provides insights into a catalytic versatility.

    Jeong Sun Kim;Sun Shin Cha;Hyun Ju Kim;Tae Jip Kim

  • RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.

    Hyun Soo Cho;Shinya Hayami;Gouji Toyokawa;Kazuhiro Maejima

  • Histone Lysine Methyltransferase SETD8 Promotes Carcinogenesis by Deregulating PCNA Expression

    Masashi Takawa;Hyun Soo Cho;Shinya Hayami;Gouji Toyokawa

  • Cyclomaltodextrinase, Neopullulanase, and Maltogenic Amylase Are Nearly Indistinguishable from Each Other

    Hee Seob Lee;Min Sung Kim;Hyun Soo Cho;Jung In Kim

  • High-Resolution Crystal Structures of Δ5-3-Ketosteroid Isomerase with and without a Reaction Intermediate Analogue

    Suhng Wook Kim;Sun Shin Cha;Hyun Soo Cho;Jeong Sun Kim

  • Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B

    Hyun Soo Cho;Tadahiro Shimazu;Gouji Toyokawa;Gouji Toyokawa;Yataro Daigo;Yataro Daigo

  • Crystal structure of hyperthermophilic esterase EstE1 and the relationship between its dimerization and thermostability properties

    Jung Sue Byun;Jin Kyu Rhee;Nam Doo Kim;Jeong Hyeok Yoon

  • Parkin directly modulates 26S proteasome activity.

    Ji Won Um;Eunju Im;Hyun Jung Lee;Boram Min

  • Interference of quorum sensing and virulence of the rice pathogen Burkholderia glumae by an engineered endophytic bacterium

    Hyun Soo Cho;Soo Young Park;Choong Min Ryu;Jihyun F. Kim

  • Decreased catalase expression and increased susceptibility to oxidative stress in primary cultured corneal fibroblasts from patients with granular corneal dystrophy type II.

    Seung-il Choi;Tae-im Kim;Kyu Seo Kim;Bong-Yoon Kim

  • Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.

    Hyun Soo Cho;Gildon Choi;Kwan Yong Choi;Byung Ha Oh

  • Spread of Mutant Middle East Respiratory Syndrome Coronavirus with Reduced Affinity to Human CD26 during the South Korean Outbreak

    Yuri Kim;Shinhye Cheon;Chan Ki Min;Kyung Mok Sohn

  • Identification of lipopolysaccharide-binding peptide regions within HMGB1 and their effects on subclinical endotoxemia in a mouse model

    Ju Ho Youn;Man Sup Kwak;Jie Wu;Eun Sook Kim

  • Crystal Structure of Δ5-3-Ketosteroid Isomerase from Pseudomonas testosteroni in Complex with Equilenin Settles the Correct Hydrogen Bonding Scheme for Transition State Stabilization

    Hyun Soo Cho;Nam Chul Ha;Gildon Choi;Hyun Ju Kim

  • Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy.

    Joong Jae Lee;Hyo Jung Choi;Misun Yun;Yingjin Kang

Frequent Co-Authors

Nam-Chul Ha
Nam-Chul Ha Seoul National University
Byung-Ha Oh
Byung-Ha Oh Korea Advanced Institute of Science and Technology
Daniel J. Leahy
Daniel J. Leahy Johns Hopkins University School of Medicine
Hak-Sung Kim
Hak-Sung Kim Hanyang University
Thomas Walz
Thomas Walz Rockefeller University
Sung Ho Ryu
Sung Ho Ryu Pohang University of Science and Technology
Wan Kyun Chung
Wan Kyun Chung Pohang University of Science and Technology
Woo Taek Kim
Woo Taek Kim Yonsei University
Jong-Lam Lee
Jong-Lam Lee Pohang University of Science and Technology
Kwang S. Kim
Kwang S. Kim Ulsan National Institute of Science and Technology

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