2026 Fritz J. Sedlazeck: Genetics Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Rising Stars	57	187	187	23	23	210	21686
Genetics	64	2743	2597	1205	1129	205	29444

Research.com Recognitions

2025 - Research.com Rising Stars Award

Overview

Fritz J. Sedlazeck is affiliated with Baylor College of Medicine in the United States. Their research portfolio encompasses a wide range of topics within the field of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology, Genetics, Cancer Research, Plant Science, and Infectious Diseases.

Their published work frequently appears in prominent scientific venues, primarily:

bioRxiv (Cold Spring Harbor Laboratory)
Nature Communications
Nature Biotechnology
Genome Research
Genome biology

Sedlazeck has contributed extensively to the study of genomics with particular interests in:

Genomics and Phylogenetic Studies
Genomics and Rare Diseases
Cancer Genomics and Diagnostics
Genomic variations and chromosomal abnormalities
Chromosomal and Genetic Variations
Genomics and Chromatin Dynamics
Molecular Biology Techniques and Applications

Among their recent papers are:

"The complete sequence of a human genome" (2022) published in Science
"Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato" (2020) published in Cell
"Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes" (2020) published in Nature Biotechnology
"Targeted nanopore sequencing with Cas9-guided adapter ligation" (2020) published in Nature Biotechnology
"A robust benchmark for detection of germline large deletions and insertions" (2020) published in Nature Biotechnology

Frequent collaborators in Sedlazeck's research include:

Medhat Mahmoud
Justin M. Zook
Luis F. Paulin
Richard A. Gibbs
Nathan D. Olson

The breadth of Sedlazeck's research reflects a strong emphasis on genomic structural variation and its applications to human health and crop science. Their publications in leading journals illuminate advances in sequencing technologies, genome assembly, and genomic variant benchmarking, contributing to fields such as cancer genomics and crop improvement.

Best Publications

Phased diploid genome assembly with single-molecule real-time sequencing

Chen-Shan Chin;Paul Peluso;Fritz J Sedlazeck;Maria Nattestad

2040
Citations
GenomeScope: fast reference-free genome profiling from short reads

Gregory W Vurture;Fritz J Sedlazeck;Maria Nattestad;Charles J Underwood

1912
Citations
Accurate detection of complex structural variations using single-molecule sequencing.

Fritz J. Sedlazeck;Philipp Rescheneder;Moritz Smolka;Han Fang

1876
Citations
Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome.

Aaron M. Wenger;Paul Peluso;William J. Rowell;Pi-Chuan Chang

1807
Citations
Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast.

Daniel C. Jeffares;Clemency Jolly;Mimoza Hoti;Doug Speed

846
Citations
Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato.

Michael Alonge;Xingang Wang;Matthias Benoit;Matthias Benoit;Sebastian Soyk

805
Citations
Structural variant calling: the long and the short of it

Medhat Mahmoud;Nastassia Gobet;Nastassia Gobet;Diana Ivette Cruz-Dávalos;Diana Ivette Cruz-Dávalos;Ninon Mounier

760
Citations
The pineapple genome and the evolution of CAM photosynthesis

Ray Ming;Ray Ming;Robert VanBuren;Robert VanBuren;Robert VanBuren;Ching Man Wai;Ching Man Wai;Haibao Tang;Haibao Tang

624
Citations
Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes.

Kishwar Shafin;Trevor Pesout;Ryan Lorig-Roach;Marina Haukness

615
Citations
RaGOO: fast and accurate reference-guided scaffolding of draft genomes

Michael Alonge;Sebastian Soyk;Srividya Ramakrishnan;Xingang Wang

570
Citations
Updating benchtop sequencing performance comparison

Sebastian Jünemann;Sebastian Jünemann;Fritz Joachim Sedlazeck;Karola Prior;Andreas Albersmeier

539
Citations
Piercing the dark matter: bioinformatics of long-range sequencing and mapping

Fritz J. Sedlazeck;Hayan Lee;Charlotte A. Darby;Michael C. Schatz;Michael C. Schatz

482
Citations
A robust benchmark for detection of germline large deletions and insertions.

Justin M. Zook;Nancy F. Hansen;Nathan D. Olson;Lesley Chapman

437
Citations
NextGenMap: Fast and accurate read mapping in highly polymorphic genomes

Fritz J. Sedlazeck;Philipp Rescheneder;Arndt von Haeseler

430
Citations
Targeted nanopore sequencing with Cas9-guided adapter ligation

Timothy Gilpatrick;Isac Lee;James E Graham;Etienne Raimondeau

368
Citations
Towards population-scale long-read sequencing.

Wouter De Coster;Matthias H. Weissensteiner;Fritz J. Sedlazeck

235
Citations
Chromosomal-level assembly of the Asian seabass genome using long sequence reads and multi-layered scaffolding

Shubha Vij;Heiner Kuhl;Inna S. Kuznetsova;Inna S. Kuznetsova;Aleksey Komissarov

184
Citations
A multi-task convolutional deep neural network for variant calling in single molecule sequencing

Ruibang Luo;Ruibang Luo;Fritz J. Sedlazeck;Tak-Wah Lam;Michael C. Schatz

182
Citations
Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Maria Nattestad;Sara Goodwin;Karen Ng;Timour Baslan

170
Citations
Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing.

Isac Lee;Roham Razaghi;Timothy Gilpatrick;Michael Molnar

164
Citations

Frequent Co-Authors

Michael C. Schatz Johns Hopkins University

Arndt von Haeseler University of Vienna

Justin M. Zook National Institute of Standards and Technology

Chen-Shan Chin Pacific Biosciences (United States)

Tobias Marschall Heinrich Heine University Düsseldorf

Zachary B. Lippman Cold Spring Harbor Laboratory

Richard A. Gibbs Baylor College of Medicine

Christopher E. Mason Cornell University

Eric Boerwinkle The University of Texas Health Science Center at Houston

Jochen B. W. Wolf Ludwig-Maximilians-Universität München

External Links

Personal website of Fritz J. Sedlazeck

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