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Overview

David S. King is affiliated with the University of California, Berkeley in the United States. Their research spans multiple fields within medicine and environmental science, with a particular focus on neurology, oncology, molecular biology, and cognitive neuroscience. The subfields they have contributed to include neurology, health, toxicology and mutagenesis, oncology, and molecular biology.

The main topics of King's work cover several specialized areas: neuroblastoma research and treatments, PARP inhibition in cancer therapy, cell death mechanisms and regulation, Parkinson's disease mechanisms and treatments, neurological disorders and treatments, neurobiology of language and bilingualism, and mercury impact and mitigation studies.

Their recent publications include the following papers:

  • Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma, 2020, published in EBioMedicine
  • MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma, 2020, published in Oncotarget
  • Increased Replication Stress Determines ATR Inhibitor Sensitivity in Neuroblastoma Cells, 2021, published in Cancers
  • Sex differences in Parkinson disease-associated episodic memory and processing speed deficits, 2023, published in Journal of the International Neuropsychological Society
  • Phosphorylation of a PDZ Domain Extension Modulates Binding Affinity and Interdomain Interactions in Postsynaptic Density-95 (PSD-95) Protein, a Membrane-associated Guanylate Kinase (MAGUK), 2020, published in UNC Libraries

King has collaborated frequently with several researchers, including:

  • Helen E. Bryant
  • Sally L. George
  • Christopher J. Lord
  • Louis Chesler
  • Polly Gravells

Their work has been published in various venues, notable among them are:

  • EBioMedicine
  • Oncotarget
  • Cancers
  • Journal of the International Neuropsychological Society
  • Environmental Geochemistry and Health

Best Publications

  • Phase transitions in the assembly of multivalent signalling proteins

    Pilong Li;Sudeep Banjade;Hui Chun Cheng;Soyeon Kim

  • Phase separation of signaling molecules promotes T cell receptor signal transduction

    Xiaolei Su;Xiaolei Su;Jonathon A. Ditlev;Jonathon A. Ditlev;Enfu Hui;Enfu Hui;Wenmin Xing;Wenmin Xing

  • Addition of p-Azido-l-phenylalanine to the Genetic Code of Escherichia coli

    Jason W. Chin;Stephen W. Santoro;Andrew B. Martin;David S. King

  • Structure and Function of a Human TAFII250 Double Bromodomain Module

    Raymond H. Jacobson;Andreas G. Ladurner;David S. King;Robert Tjian

  • Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli

    Jason W. Chin;Andrew B. Martin;David S. King;Lei Wang

  • A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis.

    David S. King;Cynthia G. Fields;Gregg B. Fields

  • Identification of a candidate therapeutic autophagy-inducing peptide

    Sanae Shoji-Kawata;Rhea Sumpter;Matthew J Leveno;Grant R. Campbell;Grant R. Campbell

  • A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress

    Onn Brandman;Jacob Stewart-Ornstein;Daisy Wong;Adam Larson

  • General approach to the synthesis of short .alpha.-helical peptides

    David Y. Jackson;David S. King;Jean Chmielewski;Sunil Singh

  • An expanded genetic code with a functional quadruplet codon

    J. Christopher Anderson;Ning Wu;Stephen W. Santoro;Vishva Lakshman

  • Spider toxins activate the capsaicin receptor to produce inflammatory pain

    Jan Siemens;Sharleen Zhou;Rebecca Piskorowski;Rebecca Piskorowski;Tetsuro Nikai

  • Generation of a bacterium with a 21 amino acid genetic code.

    Ryan A Mehl;J Christopher Anderson;Stephen W Santoro;Lei Wang

  • A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain.

    Christopher J. Bohlen;Alexander T. Chesler;Reza Sharif-Naeini;Katalin F. Medzihradszky

  • A genetically encoded photocaged amino acid

    Ning Wu;Alexander Deiters;T. Ashton Cropp;David King

  • Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

    A.T. Whiteley;J.B. Eaglesham;C.C. de Oliveira Mann;B.R. Morehouse

  • An efficient system for the evolution of aminoacyl-tRNA synthetase specificity.

    Stephen W. Santoro;Lei Wang;Brad Herberich;David S. King

  • A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

    Christopher J. Bohlen;Avi Priel;Sharleen Zhou;David King

  • Selectivity of chromatin-remodelling cofactors for ligand-activated transcription.

    Bryan Lemon;Carla Inouye;David S. King;Robert Tjian

  • Studies on the Mechanism of Action of Isoniazid and Ethionamide in the Chemotherapy of Tuberculosis

    Kai Johnsson;David S. King;Peter G. Schultz

  • High yield bacterial expression of active c‐Abl and c‐Src tyrosine kinases

    Markus A. Seeliger;Matthew Young;M. Nidanie Henderson;Patricia Pellicena

Frequent Co-Authors

John C. Stephenson
John C. Stephenson National Institute of Standards and Technology
Peter G. Schultz
Peter G. Schultz Scripps Research Institute
David E. Wemmer
David E. Wemmer University of California, Berkeley
Amy S. Lee
Amy S. Lee University of Southern California
John J. Mekalanos
John J. Mekalanos Harvard Medical School
James W. Fristrom
James W. Fristrom University of California, Berkeley
Robin M. Hochstrasser
Robin M. Hochstrasser University of Pennsylvania
Alexander Pines
Alexander Pines University of California, Berkeley
Myron F. Goodman
Myron F. Goodman University of Southern California
Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University

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