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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10704
World Ranking
15077
National Ranking
276

Overview

Curzio Rüegg is affiliated with the University of Fribourg in Switzerland and has a research focus spanning biochemistry, genetics, molecular biology, and medicine. Their scholarly output includes numerous publications centered on molecular biology, oncology, immunology, biomedical engineering, and cancer research.

The primary topics of their work include advanced biosensing and bioanalysis techniques, cancer cells and metastasis, cancer immunotherapy and biomarkers, RNA interference and gene delivery, immune cells in cancer, immunotherapy and immune responses, and DNA and nucleic acid chemistry.

Recent papers authored or co-authored by Curzio Rüegg include:

  • The Crosstalk between FAK and Wnt Signaling Pathways in Cancer and Its Therapeutic Implication, 2020, International Journal of Molecular Sciences
  • Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis, 2021, Frontiers in Oncology
  • CD47 Promotes Age-Associated Deterioration in Angiogenesis, Blood Flow and Glucose Homeostasis, 2020, Cells
  • DNA Origami as Emerging Technology for the Engineering of Fluorescent and Plasmonic-Based Biosensors, 2020, Materials
  • Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation, 2022, Science Translational Medicine

Frequent co-authors working alongside Rüegg include:

  • Samet Kocabey (16 joint publications)
  • Guillermo P. Acuna (9 joint publications)
  • Ivana Domljanovic (7 joint publications)
  • Oriana Coquoz (7 joint publications)
  • Michael Mayer (6 joint publications)

The scientist regularly publishes in the following venues:

  • Zenodo (CERN European Organization for Nuclear Research) - 11 publications
  • Cells - 4 publications
  • Cancers - 3 publications
  • bioRxiv (Cold Spring Harbor Laboratory) - 3 publications
  • Frontiers in Oncology - 2 publications

Best Publications

  • Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma.

    Curzio Rüegg;Aysim Yilmaz;Grégory Bieler;Jeannine Bamat

  • The tumor microenvironment and its contribution to tumor evolution toward metastasis

    Girieca Lorusso;Curzio Rüegg;Curzio Rüegg

  • Consensus guidelines for the use and interpretation of angiogenesis assays

    Patrycja Nowak-Sliwinska;Kari Alitalo;Elizabeth Allen;Andrey Anisimov

  • Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering

    C Rüegg;AA Postigo;EE Sikorski;EC Butcher

  • NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.

    Olivier Dormond;Alessandro Foletti;Cécile Paroz;Curzio Rüegg

  • Clinical applications of TNF-alpha in cancer.

    Ferdy J Lejeune;Curzio Rüegg;Danielle Liénard

  • Efficiency of recombinant human TNF in human cancer therapy

    Ferdy J. Lejeune;Danielle Liénard;Danielle Liénard;Maurice Matter;Curzio Rüegg;Curzio Rüegg

  • Sequence and tissue distribution of the integrin alpha 9 subunit, a novel partner of beta 1 that is widely distributed in epithelia and muscle.

    E L Palmer;C Rüegg;R Ferrando;R Pytela

  • Homing Phenotypes of Tumor-Specific CD8 T Cells Are Predetermined at the Tumor Site by Crosspresenting APCs

    Thomas Calzascia;Frédérick Masson;Wilma Di Berardino-Besson;Emmanuel Contassot

  • Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis.

    Inês Sofia Vala;Leila R. Martins;Natsuko Imaizumi;Raquel J. Nunes

  • Vascular integrins: pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis.

    C. Rüegg;A. Mariotti

  • Akt/PKB-Mediated Phosphorylation of Twist1 Promotes Tumor Metastasis via Mediating Cross-Talk between PI3K/Akt and TGF-β Signaling Axes

    Gongda Xue;David F. Restuccia;Qiang Lan;Debby Hynx

  • Vascular Integrins in Tumor Angiogenesis: Mediators and Therapeutic Targets

    Gian Carlo Alghisi;Curzio Rüegg

  • New insights into the mechanisms of organ-specific breast cancer metastasis.

    Girieca Lorusso;Girieca Lorusso;Curzio Rüegg;Curzio Rüegg

  • Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism.

    Sarah Garrido-Urbani;Stéphane Jemelin;Christine Deffert;Stéphanie Carnesecchi

  • Tenascin, an extracellular matrix protein, exerts immunomodulatory activities.

    Curzio R. Ruegg;Ruth Chiquet-Ehrismann;Sefik S. Alkan

  • Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: tools or decorations?

    Cristiana Sessa;Aymeric Guibal;Gianluca Del Conte;Curzio Rüegg

  • Prostaglandin E2 Promotes Integrin αVβ3-dependent Endothelial Cell Adhesion, Rac-activation, and Spreading through cAMP/PKA-dependent Signaling

    Olivier Dormond;Manuela Bezzi;Agnese Mariotti;Curzio Rüegg

  • Suppression of tumor angiogenesis through the inhibition of integrin function and signaling in endothelial cells: which side to target?

    C. Rüegg;O. Dormond;A. Foletti

  • Zoledronate Sensitizes Endothelial Cells to Tumor Necrosis Factor-induced Programmed Cell Death EVIDENCE FOR THE SUPPRESSION OF SUSTAINED ACTIVATION OF FOCAL ADHESION KINASE AND PROTEIN KINASE B/Akt

    Manuela Bezzi;Meriem Hasmim;Grégory Bieler;Olivier Dormond

Frequent Co-Authors

Mauro Delorenzi
Mauro Delorenzi University of Lausanne
Roger Stupp
Roger Stupp Northwestern University
Ruth Chiquet-Ehrismann
Ruth Chiquet-Ehrismann Friedrich Miescher Institute
Gerhard Christofori
Gerhard Christofori University of Basel
Monika E. Hegi
Monika E. Hegi University of Lausanne
Leonardo Scapozza
Leonardo Scapozza University of Geneva
Liliane Michalik
Liliane Michalik University of Lausanne
Brian A. Hemmings
Brian A. Hemmings Friedrich Miescher Institute
Karl-Heinz Krause
Karl-Heinz Krause University of Geneva
Barbara Rothen-Rutishauser
Barbara Rothen-Rutishauser University of Fribourg

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