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Christiaan P. J. de Kock

Christiaan P. J. de Kock

D-Index & Metrics

Neuroscience

D-Index
44
Citations
7616
World Ranking
7166
National Ranking
198

Overview

Christiaan P. J. de Kock is affiliated with Vrije Universiteit Amsterdam in the Netherlands and conducts research primarily in the field of neuroscience. Their work spans several subfields, including cognitive neuroscience, cellular and molecular neuroscience, molecular biology, electrical and electronic engineering, and biophysics.

The scientist's research covers multiple main topics, such as neural dynamics and brain function, neuroscience and neuropharmacology research, neuroscience and neural engineering, advanced memory and neural computing, single-cell and spatial transcriptomics, functional brain connectivity studies, and memory and neural mechanisms.

Recent publications demonstrate a focus on neural architecture, synaptic communication, and comparative analysis of neuronal properties in the human brain. Notable recent papers include:

  • Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex (2023, Science)
  • Evolution of cortical neurons supporting human cognition (2022, Trends in Cognitive Sciences)
  • The impact of neuron morphology on cortical network architecture (2022, Cell Reports)
  • Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex (2022, Cerebral Cortex)
  • Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex (2023, Science)

Frequent collaborators in their research include Huibert D. Mansvelder, Natalia A. Goriounova, Anna A. Galakhova, René Wilbers, and Djai B. Heyer.

The majority of de Kock's publications have appeared in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cerebral Cortex, Nature Neuroscience, and Science.

Their contributions to neuroscience research highlight a significant engagement with the detailed study of cortical neurons and brain function at cellular and network levels, utilizing methods from molecular biology, neuropharmacology, and electrophysiology.

Best Publications

  • Layer- and cell-type-specific suprathreshold stimulus representation in rat primary somatosensory cortex.

    C. P. J. De Kock;R. M. Bruno;H. Spors;B. Sakmann

  • Cell Type–Specific Three-Dimensional Structure of Thalamocortical Circuits in a Column of Rat Vibrissal Cortex

    Marcel Oberlaender;Christiaan P. J. de Kock;Randy M. Bruno;Alejandro Ramirez

  • Dimensions of a projection column and architecture of VPM and POm axons in rat vibrissal cortex.

    Verena C. Wimmer;Randy M. Bruno;Christiaan P.J. de Kock;Thomas Kuner

  • Spatial Organization of Neuronal Population Responses in Layer 2/3 of Rat Barrel Cortex

    Jason N. D. Kerr;Christiaan P. J. de Kock;David S. Greenberg;Randy M. Bruno

  • Human neocortical expansion involves glutamatergic neuron diversification

    Jim Berg;Staci A. Sorensen;Jonathan T. Ting;Jonathan T. Ting;Jeremy A. Miller

  • Dendritic and Axonal Architecture of Individual Pyramidal Neurons across Layers of Adult Human Neocortex

    Hemanth Mohan;Matthijs B. Verhoog;Keerthi K. Doreswamy;Guy Eyal

  • Spiking in primary somatosensory cortex during natural whisking in awake head-restrained rats is cell-type specific.

    Christiaan P. J. de Kock;Bert Sakmann

  • A community-based transcriptomics classification and nomenclature of neocortical cell types

    Rafael Yuste;Michael Hawrylycz;Nadia Aalling;Argel Aguilar-Valles

  • Cell Type–Specific Thalamic Innervation in a Column of Rat Vibrissal Cortex

    Hanno-Sebastian Meyer;Verena C. Wimmer;Mike Hemberger;Randy M. Bruno

  • Number and Laminar Distribution of Neurons in a Thalamocortical Projection Column of Rat Vibrissal Cortex

    Hanno-Sebastian Meyer;Verena C. Wimmer;Marcel Oberlaender;Christiaan de Kock

  • Unique membrane properties and enhanced signal processing in human neocortical neurons

    Guy Eyal;Matthijs B Verhoog;Guilherme Testa-Silva;Yair Deitcher

  • Label-free live brain imaging and targeted patching with third-harmonic generation microscopy

    Stefan Witte;Adrian Negrean;Johannes C. Lodder;Christiaan P. J. de Kock

  • Layer-Specific Modulation of the Prefrontal Cortex by Nicotinic Acetylcholine Receptors

    Rogier B. Poorthuis;Bernard Bloem;Benita Schak;Jordi Wester

  • State and location dependence of action potential metabolic cost in cortical pyramidal neurons

    Stefan Hallermann;Christiaan P J de Kock;Greg J Stuart;Maarten H P Kole;Maarten H P Kole

  • High Bandwidth Synaptic Communication and Frequency Tracking in Human Neocortex

    Guilherme Testa-Silva;Matthijs B. Verhoog;Daniele Linaro;Christiaan P. J. de Kock

  • Human Cortical Pyramidal Neurons: From Spines to Spikes via Models.

    Guy Eyal;Matthijs B. Verhoog;Matthijs B. Verhoog;Guilherme Testa-Silva;Yair Deitcher

  • Dendrites Impact the Encoding Capabilities of the Axon

    Guy Eyal;Huibert D. Mansvelder;Christiaan P.J. de Kock;Idan Segev;Idan Segev

  • Large and fast human pyramidal neurons associate with intelligence

    Natalia A. Goriounova;Djai B. Heyer;Rene Wilbers;Matthijs B. Verhoog

  • Driver or Coincidence Detector: Modal Switch of a Corticothalamic Giant Synapse Controlled by Spontaneous Activity and Short-Term Depression

    Alexander Groh;Christiaan P. J. de Kock;Verena C. Wimmer;Bert Sakmann

  • Mechanisms underlying the rules for associative plasticity at adult human neocortical synapses

    Matthijs B. Verhoog;Natalia A. Goriounova;Joshua Obermayer;Jasper Stroeder

  • Three-dimensional axon morphologies of individual layer 5 neurons indicate cell type-specific intracortical pathways for whisker motion and touch

    Marcel Oberlaender;Zimbo S. R. M. Boudewijns;Tatjana Kleele;Huibert D. Mansvelder

  • Hyperconnectivity and Slow Synapses during Early Development of Medial Prefrontal Cortex in a Mouse Model for Mental Retardation and Autism

    Guilherme Testa-Silva;Alex Loebel;Michele Giugliano;Michele Giugliano;Michele Giugliano;Christiaan P.J. de Kock

Frequent Co-Authors

Huibert D. Mansvelder
Huibert D. Mansvelder Vrije Universiteit Amsterdam
Michele Giugliano
Michele Giugliano University of Modena and Reggio Emilia
Idan Segev
Idan Segev Hebrew University of Jerusalem
Javier DeFelipe
Javier DeFelipe Technical University of Madrid
Martin Klein
Martin Klein Vrije Universiteit Amsterdam
Ed S. Lein
Ed S. Lein University of Washington
Moritz Helmstaedter
Moritz Helmstaedter Max Planck Society
Michael Hawrylycz
Michael Hawrylycz Allen Institute for Brain Science
Randy M. Bruno
Randy M. Bruno University of Oxford

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