His primary scientific interests are in Neuroscience, Spinal muscular atrophy, Survival of motor neuron, Neuromuscular junction and Denervation. The various areas that he examines in his Neuroscience study include Cancer research, Postsynaptic potential, Schwann cell, Cell biology and Skeletal muscle. His work on Perisynaptic schwann cells as part of general Postsynaptic potential study is frequently linked to Structure and function, therefore connecting diverse disciplines of science.
His work carried out in the field of Cell biology brings together such families of science as Mutation, Messenger RNA, Alternative splicing, Stimulation and SMN1. In his articles, Chien-Ping Ko combines various disciplines, including Neuromuscular junction and Active zone. His Denervation research is multidisciplinary, relying on both Pathogenesis, Pathology, Muscle weakness, Synapse and Muscle atrophy.
His scientific interests lie mostly in Neuroscience, Neuromuscular junction, Spinal muscular atrophy, Cell biology and Perisynaptic schwann cells. His Neuroscience research includes elements of Schwann cell, Postsynaptic potential and Neurotransmission. Chien-Ping Ko has researched Neuromuscular junction in several fields, including Biophysics, Synapse, Anatomy and Acetylcholine receptor.
His Spinal muscular atrophy research incorporates elements of Motor neuron, Bioinformatics and Pathology. His Cell biology study which covers Stimulation that intersects with Neurotrophic factors, Neurotrophin and Myocyte. His biological study spans a wide range of topics, including Postsynaptic specialization, Tripartite synapse, Extracellular matrix and Nerve injury.
His scientific interests lie mostly in Spinal muscular atrophy, Neuroscience, SMN1, Bioinformatics and Motor neuron. His research on Spinal muscular atrophy focuses in particular on Survival of motor neuron. In general Neuroscience study, his work on Nervous system, Spinal cord and Neuromuscular junction often relates to the realm of Neurodegeneration, thereby connecting several areas of interest.
His study in Stem cell extends to Neuromuscular junction with its themes. The concepts of his SMN1 study are interwoven with issues in Molecular biology and Atrophy. His Neurotransmission research includes themes of Synapse, Electrophysiology, Astrocyte and Synaptogenesis.
Chien-Ping Ko mostly deals with Spinal muscular atrophy, SMN1, Survival of motor neuron, Bioinformatics and Clinical trial. The Spinal muscular atrophy study combines topics in areas such as Neuroscience, Muscle atrophy and Exon. His study ties his expertise on Neurotransmission together with the subject of Neuroscience.
His studies deal with areas such as Motor neuron, Myostatin and Follistatin as well as Muscle atrophy. His study in Exon is interdisciplinary in nature, drawing from both Molecular biology, Cancer research, Genetically modified mouse and Central nervous system. His Clinical trial research incorporates themes from Drug discovery, Gene splicing and Dosing.
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SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
Nikolai A. Naryshkin;Marla Weetall;Amal Dakka;Jana Narasimhan.
Aberrant Patterning of Neuromuscular Synapses in Choline Acetyltransferase-Deficient Mice
Eugene P. Brandon;Weichun Lin;Kevin A. D'Amour;Donald P. Pizzo.
The Journal of Neuroscience (2003)
Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy
Karen K. Y. Ling;Rebecca M. Gibbs;Zhihua Feng;Chien-Ping Ko.
Human Molecular Genetics (2012)
Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)
Hasane Ratni;Martin Ebeling;John Baird;Stefanie Bendels.
Journal of Medicinal Chemistry (2018)
Mechanisms and Roles of Axon-Schwann Cell Interactions
Gabriel Corfas;Miguel Omar Velardez;Chien Ping Ko;Nancy Ratner.
The Journal of Neuroscience (2004)
Synaptic Defects in the Spinal and Neuromuscular Circuitry in a Mouse Model of Spinal Muscular Atrophy
Karen K. Y. Ling;Ming-Yi Lin;Brian Zingg;Zhihua Feng.
PLOS ONE (2010)
Glial Cells Maintain Synaptic Structure and Function and Promote Development of the Neuromuscular Junction In Vivo
Linga V Reddy;Samir Koirala;Yoshie Sugiura;Albert A Herrera.
Correlations between active zone ultrastructure and synaptic function studied with freeze-fracture of physiologically identified neuromuscular junctions.
J. W. Propst;Chien-Ping Ko.
The Journal of Neuroscience (1987)
Differential Effects of Neurotrophins and Schwann Cell-Derived Signals on Neuronal Survival/Growth and Synaptogenesis
H. Benjamin Peng;Jie-Fei Yang;Zhengshan Dai;Chi Wai Lee.
The Journal of Neuroscience (2003)
Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis.
Young-Eun Yoo;Chien-Ping Ko.
Experimental Neurology (2011)
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