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D-Index
42
Citations
5910
World Ranking
7709
National Ranking
3308

Overview

Chien-Ping Ko is affiliated with the University of Southern California in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a strong focus on Molecular Biology and Genetics as principal subfields. Additional subfields include Surgery, Cellular and Molecular Neuroscience, and Biomedical Engineering.

Their scientific contributions center on topics such as Neurogenetic and Muscular Disorders Research, RNA modifications and cancer, RNA Research and Splicing, Congenital Anomalies and Fetal Surgery, RNA Interference and Gene Delivery, Ion channel regulation and function, and Nerve injury and regeneration.

Frequent publication venues for Chien-Ping Ko include:

  • Human Molecular Genetics
  • Journal of Clinical Investigation
  • Neuron
  • JCI Insight
  • International Journal of Molecular Sciences

Among recent published papers are:

  • Muscle-specific SMN reduction reveals motor neuron-independent disease in spinal muscular atrophy models, 2020, Journal of Clinical Investigation
  • A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses, 2023, Neuron
  • Minor snRNA gene delivery improves the loss of proprioceptive synapses on SMA motor neurons, 2020, JCI Insight
  • Activation of Muscle-Specific Kinase (MuSK) Reduces Neuromuscular Defects in the Delta7 Mouse Model of Spinal Muscular Atrophy (SMA), 2021, International Journal of Molecular Sciences
  • Perisynaptic Schwann Cells: Guardians of Neuromuscular Junction Integrity and Function in Health and Disease, 2024, Cold Spring Harbor Perspectives in Biology

Chien-Ping Ko has collaborated frequently with other researchers, including:

  • Zhihua Feng
  • Karen Ling
  • Jeong-Ki Kim
  • Narendra Nath Jha
  • Umrao R. Monani

Best Publications

  • SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

    Nikolai A. Naryshkin;Marla Weetall;Amal Dakka;Jana Narasimhan

  • Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)

    Hasane Ratni;Martin Ebeling;John Baird;Stefanie Bendels

  • Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy

    Karen K. Y. Ling;Rebecca M. Gibbs;Zhihua Feng;Chien-Ping Ko

  • Mechanisms and Roles of Axon-Schwann Cell Interactions

    Gabriel Corfas;Miguel Omar Velardez;Chien Ping Ko;Nancy Ratner

  • Aberrant Patterning of Neuromuscular Synapses in Choline Acetyltransferase-Deficient Mice

    Eugene P. Brandon;Weichun Lin;Kevin A. D'Amour;Donald P. Pizzo

  • Synaptic Defects in the Spinal and Neuromuscular Circuitry in a Mouse Model of Spinal Muscular Atrophy

    Karen K. Y. Ling;Ming-Yi Lin;Brian Zingg;Zhihua Feng

  • Glial Cells Maintain Synaptic Structure and Function and Promote Development of the Neuromuscular Junction In Vivo

    Linga V Reddy;Samir Koirala;Yoshie Sugiura;Albert A Herrera

  • Differential Effects of Neurotrophins and Schwann Cell-Derived Signals on Neuronal Survival/Growth and Synaptogenesis

    H. Benjamin Peng;Jie-Fei Yang;Zhengshan Dai;Chi Wai Lee

  • Correlations between active zone ultrastructure and synaptic function studied with freeze-fracture of physiologically identified neuromuscular junctions.

    J. W. Propst;Chien-Ping Ko

  • Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis.

    Young-Eun Yoo;Chien-Ping Ko

  • Astrocytes influence the severity of spinal muscular atrophy

    Hansjörg Rindt;Zhihua Feng;Chiara Mazzasette;Jacqueline J. Glascock

  • Schwann Cells Promote Synaptogenesis at the Neuromuscular Junction via Transforming Growth Factor-β1

    Unknown

  • Perisynaptic Schwann Cells at the Neuromuscular Synapse: Adaptable, Multitasking Glial Cells

    Chien-Ping Ko;Richard Robitaille

  • Synaptic transmission between rat superior cervical ganglion neurons in dissociated cell cultures.

    Chien Ping Ko;Harold Burton;Mary I. Johnson;Richard P. Bunge

  • Schwann Cells Express Active Agrin and Enhance Aggregation of Acetylcholine Receptors on Muscle Fibers

    Jie Fei Yang;Guan Cao;Samir Koirala;Linga V. Reddy

  • The role of glial cells in the formation and maintenance of the neuromuscular junction.

    Zhihua Feng;Chien-Ping Ko

  • A lectin, peanut agglutinin, as a probe for the extracellular matrix in living neuromuscular junctions

    Chien-Ping Ko

  • Muscle-specific SMN reduction reveals motor neuron–independent disease in spinal muscular atrophy models

    Jeong-Ki Kim;Narendra N. Jha;Zhihua Feng;Michelle R. Faleiro

  • Pathological impact of SMN2 mis-splicing in adult SMA mice

    Kentaro Sahashi;Karen K Y Ling;Yimin Hua;John Erby Wilkinson

  • Anatomical and physiological observations on synapses formed on isolated autonomic neurons in tissue culture

    Richard P. Bunge;Rosemary Rees;Patrick Wood;Harold Burton

  • Synaptic transmission between rat spinal cord explants and dissociated superior cervical ganglion neurons in tissue culture.

    Chien-Ping Ko;Harold Burton;Richard P. Bunge

Frequent Co-Authors

Adrian R. Krainer
Adrian R. Krainer Cold Spring Harbor Laboratory
Anirvan Ghosh
Anirvan Ghosh Unity Biotechnology
Michael E. Talkowski
Michael E. Talkowski Harvard University
Gen Sobue
Gen Sobue Aichi Medical University
Nils Brose
Nils Brose Max Planck Society
Fred H. Gage
Fred H. Gage Salk Institute for Biological Studies
Richard Robitaille
Richard Robitaille University of Montreal
Ronald W. Oppenheim
Ronald W. Oppenheim Wake Forest University
Gabriel Corfas
Gabriel Corfas University of Michigan–Ann Arbor

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