World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
70
Citations
16448
World Ranking
5893
National Ranking
1805

Biology and Biochemistry

D-Index
72
Citations
16862
World Ranking
6371
National Ranking
2982

Overview

Brian G. Fox is affiliated with the University of Wisconsin-Madison in the United States. Their research spans multiple disciplines, focusing primarily on biochemistry, genetics, molecular biology, and engineering. These main fields incorporate a substantial body of work reflecting both fundamental and applied scientific inquiries.

The scientist's subfields of study include molecular biology, biomedical engineering, inorganic chemistry, biotechnology, and plant science. This diversity reflects a broad interdisciplinary approach across biological and chemical sciences.

Core topics addressed in their research encompass biofuel production and bioconversion, metal-catalyzed oxygenation mechanisms, lignin and wood chemistry, plant gene expression analysis, enzyme catalysis and immobilization, heme oxygenase-1 and carbon monoxide, and enzyme production and characterization.

Brian G. Fox has contributed to numerous scholarly articles published in highly regarded scientific venues. Frequent publication outlets include the Journal of Biological Chemistry, Biochemistry, ACS Sustainable Chemistry & Engineering, PLANT PHYSIOLOGY, and ChemBioChem.

Some of their recent papers are as follows:

  • Visualizing plant cell wall changes proves the superiority of hydrochloric acid over sulfuric acid catalyzed γ-valerolactone pretreatment, 2021, Chemical Engineering Journal
  • pHBMT1, a BAHD-family monolignol acyltransferase, mediates lignin acylation in poplar, 2021, PLANT PHYSIOLOGY
  • Multifunctional cellulases are potent, versatile tools for a renewable bioeconomy, 2021, Current Opinion in Biotechnology
  • A bacterial biosynthetic pathway for methylated furan fatty acids, 2020, Journal of Biological Chemistry
  • A structural and kinetic survey of GH5_4 endoglucanases reveals determinants of broad substrate specificity and opportunities for biomass hydrolysis, 2020, Journal of Biological Chemistry

The scientist collaborates extensively with multiple colleagues, with frequent co-authors including C.A. Bingman, Kirk A. Vander Meulen, Emily T. Beebe, Nathaniel Kuch, and Thomas C. Brunold. These collaborations suggest an active engagement in multi-author scientific research projects.

Best Publications

  • Eight histidine residues are catalytically essential in a membrane-associated iron enzyme, stearoyl-CoA desaturase, and are conserved in alkane hydroxylase and xylene monooxygenase

    John Shanklin;Edward Whittle;Brian G. Fox

  • Haloalkene oxidation by the soluble methane monooxygenase from Methylosinus trichosporium OB3b: Mechanistic and environmental implications

    Brian G. Fox;James G. Borneman;Lawrence P. Wackett;John D. Lipscomb

  • Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

    Pil Seok Chae;Søren G F Rasmussen;Rohini R. Rana;Kamil Gotfryd

  • Methane monooxygenase from Methylosinus trichosporium OB3b. Purification and properties of a three-component system with high specific activity from a type II methanotroph.

    B. G. Fox;W. A. Froland;J. E. Dege;John D Lipscomb

  • A Transient Intermediate of the Methane Monooxygenase Catalytic Cycle Containing an FeIVFeIV Cluster

    Sang Kyu Lee;Brian G. Fox;Wayne A. Froland;John D. Lipscomb

  • Stearoyl-acyl carrier protein delta 9 desaturase from Ricinus communis is a diiron-oxo protein.

    Brian G. Fox;John Shanklin;Chris Somerville;Eckard Munck

  • Evolution and Ecology of Actinobacteria and Their Bioenergy Applications.

    Gina R. Lewin;Camila Carlos;Camila Carlos;Marc G. Chevrette;Heidi A. Horn

  • A combined approach to improving large-scale production of tobacco etch virus protease.

    Paul G. Blommel;Brian G. Fox

  • A HIGH-VALENT NONHEME IRON INTERMEDIATE. STRUCTURE AND PROPERTIES OF FE2(MU -O)2(5-ME-TPA)2(CLO4)3

    Yanhong Dong;Hiroshi Fujii;Michael P. Hendrich;Randolph A. Leising

  • Evidence for a mu-oxo-bridged binuclear iron cluster in the hydroxylase component of methane monooxygenase. Mössbauer and EPR studies.

    B G Fox;K K Surerus;E Münck;J D Lipscomb

  • Mössbauer studies of alkane ω-hydroxylase: Evidence for a diiron cluster in an integral-membrane enzyme

    John Shanklin;Catalina Achim;Hermann Schmidt;Brian G. Fox

  • Resonance Raman evidence for an Fe-O-Fe center in stearoyl-ACP desaturase. Primary sequence identity with other diiron-oxo proteins.

    Brian G. Fox;John Shanklin;Jingyuan Ai;Thomas M. Loehr

  • Peroxodiferric intermediate of stearoyl-acyl carrier protein delta 9 desaturase: oxidase reactivity during single turnover and implications for the mechanism of desaturation.

    J. A. Broadwater;Jingyuan Ai;T. M. Loehr;J. Sanders-Loehr

  • X-ray structure of a mammalian stearoyl-CoA desaturase.

    Yonghong Bai;Jason G. McCoy;Elena J. Levin;Pablo Sobrado

  • Structure and mechanism of mouse cysteine dioxygenase

    Jason G. McCoy;Lucas J. Bailey;Eduard Bitto;Craig A. Bingman

  • The Power of Asymmetry: Architecture and Assembly of the Gram-Negative Outer Membrane Lipid Bilayer

    Jeremy C. Henderson;Shawn M. Zimmerman;Alexander A. Crofts;Joseph M. Boll

  • Enhanced bacterial protein expression during auto-induction obtained by alteration of lac repressor dosage and medium composition.

    Paul G. Blommel;Katie J. Becker;Petar Duvnjak;Brian G. Fox

  • High-valent transition metal chemistry. Moessbauer and EPR studies of high-spin (S = 2) iron(IV) and intermediate-spin (S = 3/2) iron(III) complexes with a macrocyclic tetraamido-N ligand

    Kimberly L. Kostka;Brian G. Fox;Michael P. Hendrich;Terrence J. Collins

  • Recombinant Toluene-4-monooxygenase: Catalytic and Mössbauer Studies of the Purified Diiron and Rieske Components of a Four-Protein Complex†

    Jeremie D. Pikus;Joey M. Studts;Catalina Achim;Karl E. Kauffmann

  • Cloning and sequence analysis of two Pseudomonas flavoprotein xenobiotic reductases.

    David S. Blehert;Brian G. Fox;Glenn H. Chambliss

  • Complex formation between the protein components of methane monooxygenase from Methylosinus trichosporium OB3b. Identification of sites of component interaction.

    B. G. Fox;Y. Liu;J. E. Dege;John D Lipscomb

Frequent Co-Authors

George N. Phillips
George N. Phillips Rice University
John L. Markley
John L. Markley University of Wisconsin–Madison
Eckard Münck
Eckard Münck Carnegie Mellon University
John D. Lipscomb
John D. Lipscomb University of Minnesota
Paul D. Adams
Paul D. Adams Lawrence Berkeley National Laboratory
Cameron R. Currie
Cameron R. Currie University of Wisconsin–Madison
Trent R. Northen
Trent R. Northen Lawrence Berkeley National Laboratory
Brian F. Volkman
Brian F. Volkman Medical College of Wisconsin
Michael P. Hendrich
Michael P. Hendrich Carnegie Mellon University
Michael R. Sussman
Michael R. Sussman University of Wisconsin–Madison

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