D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 8,980 134 World Ranking 9311 National Ranking 115

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Biochemistry, EF-Tu, Protein biosynthesis, Kinetin and Cell biology. His EF-Tu study is related to the wider topic of Transfer RNA. His Transfer RNA research is multidisciplinary, incorporating elements of Allosteric regulation, Biophysics, Guanosine triphosphate and Ternary complex.

He combines subjects such as Elongation factor, Proteolytic enzymes, Protein degradation and DNA synthesis with his study of Protein biosynthesis. He has researched Kinetin in several fields, including Cell cycle and Cytokinin. His studies deal with areas such as Cell culture, Cell and Ageing as well as Cell biology.

His most cited work include:

  • Crystal Structure of the Ternary Complex of Phe-tRNAPhe, EF-Tu, and a GTP Analog (762 citations)
  • Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography. (339 citations)
  • RNA Biochemistry and Biotechnology (295 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Biochemistry, EF-Tu, Elongation factor, Transfer RNA and GTP'. His Biochemistry study frequently links to related topics such as Molecular biology. The EF-Tu study combines topics in areas such as Escherichia coli, GTPase, Stereochemistry and Ternary complex.

His Elongation factor research includes themes of Amino acid, Cell culture, Biosynthesis, Ageing and Cell biology. His Transfer RNA research incorporates themes from Ribonuclease, Biophysics, Guanosine triphosphate and Binding site. His GTP' study combines topics from a wide range of disciplines, such as Thermus aquaticus, Computational biology and Alanine.

He most often published in these fields:

  • Biochemistry (50.61%)
  • EF-Tu (29.88%)
  • Elongation factor (23.78%)

What were the highlights of his more recent work (between 1999-2011)?

  • Biochemistry (50.61%)
  • Molecular biology (14.02%)
  • Kinetin (8.54%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Biochemistry, Molecular biology, Kinetin, Cell biology and Ageing. His study in Cell, EF-Tu, Escherichia coli, Glycation and RNA falls under the purview of Biochemistry. The concepts of his EF-Tu study are interwoven with issues in Coiled coil and Mutant.

In his study, which falls under the umbrella issue of RNA, Transfer RNA is strongly linked to Crystal structure. His Molecular biology research incorporates elements of DNA damage, Elongation factor, Gene and Antibody, Phage display. His Kinetin research integrates issues from Plant hormone, DNA, Gas chromatography–mass spectrometry, Healthy subjects and Cytokinin.

Between 1999 and 2011, his most popular works were:

  • Heat shock response and ageing: mechanisms and applications. (185 citations)
  • Mild stress-induced stimulation of heat-shock protein synthesis and improved functional ability of human fibroblasts undergoing aging in vitro. (100 citations)
  • Reduced levels of oxidized and glycoxidized proteins in human fibroblasts exposed to repeated mild heat shock during serial passaging in vitro. (81 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Brian F.C. Clark focuses on Biochemistry, Kinetin, Heat shock protein, Hormesis and Glycation. He specializes in Biochemistry, namely Urine. His Kinetin research also works with subjects such as

  • Cytokinin that connect with fields like DNA, Enzyme and Biological activity,
  • Tissue culture, Plant cell, Signal transduction, Callus and Cell division most often made with reference to Plant hormone.

Cell biology and Ageing are fields of study that intersect with his Hormesis research. His study in Glycation is interdisciplinary in nature, drawing from both Reactive oxygen species, Oxidative phosphorylation, Serum albumin and Bovine serum albumin. His research integrates issues of Molecular biology, Hsp90 and Stimulation in his study of Hsp70.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Crystal Structure of the Ternary Complex of Phe-tRNAPhe, EF-Tu, and a GTP Analog

Poul Nissen;Morten Kjeldgaard;Søren Thirup;Galina Polekhina.
Science (1995)

1055 Citations

Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.

T. F. M. La Cour;J. Nyborg;S. Thirup;B. F. C. Clark.
The EMBO Journal (1985)

515 Citations

RNA Biochemistry and Biotechnology

Jan Barciszewski;Brian F. C. Clark.
(1999)

455 Citations

Eukaryotic protein elongation factors.

Bent Riis;Suresh I.S. Rattan;Brian F.C. Clark;William C. Merrick.
Trends in Biochemical Sciences (1990)

375 Citations

The GTP binding motif: variations on a theme.

Morten Kjeldgaard;Jens Nyborg;Brian F. C. Clark.
The FASEB Journal (1996)

339 Citations

A model for the tertiary structure of p21, the product of the ras oncogene

F. Mccormick;B. F. C. Clark;T. F. M. La Cour;M. Kjeldgaard.
Science (1985)

291 Citations

Kinetin delays the onset of ageing characteristics in human fibroblasts.

S.I.S. Rattan;B.F.C. Clark.
Biochemical and Biophysical Research Communications (1994)

254 Citations

Heat shock response and ageing: mechanisms and applications.

Philippe Verbeke;Jannik Fonager;Brian F.C. Clark;Suresh I.S. Rattan.
Cell Biology International (2001)

242 Citations

Primary structure of elongation factor Tu from Escherichia coli.

K. Arai;B. F. C. Clark;L. Duffy;M. D. Jones.
Proceedings of the National Academy of Sciences of the United States of America (1980)

229 Citations

Protein synthesis, posttranslational modifications, and aging.

Suresh I. S. Rattan;Anastassia Derventzi;Brian F. C. Clark.
Annals of the New York Academy of Sciences (1992)

210 Citations

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