Anne K. Soutar

Overview

Best Publications

• Human lysozyme gene mutations cause hereditary systemic amyloidosis

  M. B. Pepys;P. N. Hawkins;D. R. Booth;D. M. Vigushin

  770
  Citations

• Mechanisms of Disease: genetic causes of familial hypercholesterolemia

  Anne K Soutar;Rossi P Naoumova

  763
  Citations

• Effect of the human plasma apolipoproteins and phosphatidylcholine acyl donor on the activity of lecithin: cholesterol acyltransferase.

  A. K. Soutar;C. W. Garner;H. N. Baker;J. T. Sparrow

  551
  Citations

• Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo

  Gilbert R. Thompson;Anne K. Soutar;Florentin A. Spengel;Arvind Jadhav

  372
  Citations

• Severe Hypercholesterolemia in Four British Families With the D374Y Mutation in the PCSK9 Gene: Long-Term Follow-Up and Treatment Response

  Rossi P. Naoumova;Isabella Tosi;Dilip Patel;Clare Neuwirth

  284
  Citations

• Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia

  Xi-Ming Sun;Emily R. Eden;Isabella Tosi;Clare K. Neuwirth

  242
  Citations

• Simultaneous measurement of apolipoprotein B turnover in very-low- and low-density lipoproteins in familial hypercholesterolaemia

  A.K. Soutar;N.B. Myant;G.R. Thompson

  221
  Citations

• Apolipoprotein AI mutation Arg-60 causes autosomal dominant amyloidosis.

  A K Soutar;P N Hawkins;D M Vigushin;G A Tennent

  196
  Citations

• Phenotypic variation in heterozygous familial hypercholesterolemia: a comparison of Chinese patients with the same or similar mutations in the LDL receptor gene in China or Canada.

  Simon N. Pimstone;Xi-Ming Sun;Christele du Souich;Jiri J. Frohlich

  195
  Citations

• Characterization and tissue-specific expression of the human 'very low density lipoprotein (VLDL) receptor' mRNA.

  Julie C. Webb;Dilip D. Patel;Michael D. Jones;Brian L. Knight

  184
  Citations

• Phase transitions in bilamellar vesicles. Measurements by pyrene excimer fluorescence and effect on transacylation by lecithin: cholesterol acyltransferase.

  Anne K. Soutar;Henry J. Pownall;Angela S. Hu;Louis C. Smith

  170
  Citations

• Familial hypercholesterolemia in China. Identification of mutations in the LDL-receptor gene that result in a receptor-negative phenotype.

  X M Sun;D D Patel;J C Webb;B L Knight

  152
  Citations

• Genetics, Clinical Phenotype, and Molecular Cell Biology of Autosomal Recessive Hypercholesterolemia

  Anne K. Soutar;Rossitza P. Naoumova;Linton M. Traub

  149
  Citations

• Hereditary hepatic and systemic amyloidosis caused by a new deletion/insertion mutation in the apolipoprotein AI gene.

  D R Booth;S Y Tan;S E Booth;G A Tennent

  147
  Citations

• Catabolism of lipoprotein(a) in familial hypercholesterolaemic subjects

  Brian L. Knight;Y.F.Nicholas Perombelon;Anne K. Soutar;David P. Wade

  140
  Citations

• Hormonal regulation of low-density lipoprotein (LDL) receptor activity in human hepatoma Hep G2 cells. Insulin increases LDL receptor activity and diminishes its suppression by exogenous LDL.

  David P. Wade;Brian L. Knight;Anne K. Soutar

  136
  Citations

• Variation in lipoprotein(a) concentration associated with different apolipoprotein(a) alleles.

  Y. F. N. Perombelon;A. K. Soutar;B. L. Knight

  136
  Citations

• Current management of severe homozygous hypercholesterolaemias.

  Rossi P Naoumova;Gilbert R Thompson;Anne K Soutar

  130
  Citations

• Influence of genotype at the low density lipoprotein (LDL) receptor gene locus on the clinical phenotype and response to lipid-lowering drug therapy in heterozygous familial hypercholesterolaemia

  Xi-Ming Sun;Dilip D. Patel;Brian L. Knight;Anne K. Soutar

  117
  Citations

• Genetic defects causing familial hypercholesterolaemia: identification of deletions and duplications in the LDL-receptor gene and summary of all mutations found in patients attending the Hammersmith Hospital Lipid Clinic.

  Isabella Tosi;Paola Toledo-Leiva;Clare Neuwirth;Clare Neuwirth;Rossi P. Naoumova;Rossi P. Naoumova

  115
  Citations