D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 40 Citations 10,627 88 World Ranking 17172 National Ranking 7038

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Mutation

Genetics, Genome, Human genome, Gene duplication and Segmental duplication are his primary areas of study. His work in Genetics is not limited to one particular discipline; it also encompasses Epilepsy. His Genome research is multidisciplinary, incorporating elements of Quantitative trait locus, Genome-wide association study and Indel.

His Human genome study combines topics from a wide range of disciplines, such as Expression quantitative trait loci, Genetic variation and Genetic architecture. In his study, Chromosomal rearrangement is inextricably linked to Copy-number variation, which falls within the broad field of Gene duplication. His Microdeletion syndrome research is multidisciplinary, relying on both Microcephaly and Breakpoint.

His most cited work include:

  • Fine-scale structural variation of the human genome. (914 citations)
  • Segmental Duplications and Copy-Number Variation in the Human Genome (812 citations)
  • Recurrent Rearrangements of Chromosome 1q21.1 and Variable Pediatric Phenotypes (609 citations)

What are the main themes of his work throughout his whole career to date?

Andrew J. Sharp mainly investigates Genetics, Genome, DNA methylation, Human genome and Gene. Copy-number variation, Gene duplication, Genomic imprinting, X chromosome and Tandem repeat are among the areas of Genetics where the researcher is concentrating his efforts. His studies in Gene duplication integrate themes in fields like Microdeletion syndrome, Gene rearrangement and Chromosomal rearrangement.

His Genome study combines topics from a wide range of disciplines, such as Expression quantitative trait loci, Single-nucleotide polymorphism and Computational biology. His DNA methylation research is multidisciplinary, incorporating elements of Epigenetics, Neuroscience and Comparative genomics. In his study, which falls under the umbrella issue of Human genome, Genotype is strongly linked to Genetic variation.

He most often published in these fields:

  • Genetics (70.69%)
  • Genome (30.17%)
  • DNA methylation (28.45%)

What were the highlights of his more recent work (between 2018-2021)?

  • DNA methylation (28.45%)
  • Genetics (70.69%)
  • Epigenetics (23.28%)

In recent papers he was focusing on the following fields of study:

Andrew J. Sharp mainly focuses on DNA methylation, Genetics, Epigenetics, Human genome and Gene. His DNA methylation research includes elements of T lymphocyte and In vitro. As part of his studies on Genetics, Andrew J. Sharp often connects relevant subjects like Disease.

His research in Epigenetics intersects with topics in Cancer research, Methylation, Intellectual disability and Autism, Autism spectrum disorder. His Human genome study is focused on Genome in general. His Genome study also includes

  • Trinucleotide repeat expansion most often made with reference to Chromosomal fragile site,
  • Sequence assembly together with Computational biology.

Between 2018 and 2021, his most popular works were:

  • Dual transcriptomic and epigenomic study of reaction severity in peanut-allergic children. (11 citations)
  • A Novel Framework for Characterizing Genomic Haplotype Diversity in the Human Immunoglobulin Heavy Chain Locus. (10 citations)
  • Meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex (10 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • Genetics

His primary areas of investigation include DNA methylation, Epigenetics, Genetics, Epigenome and Haplotype. His DNA methylation research incorporates elements of Cytotoxic T cell and Glatiramer acetate. His Epigenetics research integrates issues from Epigenomics, Methylation, Immunology and CpG site.

In general Genetics, his work in Gene and Human genome is often linked to Dopamine receptor binding linking many areas of study. His Epigenome study incorporates themes from Differential Methylation, Transcriptome, Meta-analysis, Disease and Genetic association. His studies deal with areas such as Structural variation, Genome, Genomics, Sequence assembly and Computational biology as well as Haplotype.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Fine-scale structural variation of the human genome.

Eray Tuzun;Andrew J Sharp;Jeffrey A Bailey;Rajinder Kaul.
Nature Genetics (2005)

1257 Citations

Segmental Duplications and Copy-Number Variation in the Human Genome

Andrew J. Sharp;Devin P. Locke;Sean D. McGrath;Ze Cheng.
American Journal of Human Genetics (2005)

1098 Citations

Recurrent Rearrangements of Chromosome 1q21.1 and Variable Pediatric Phenotypes

Heather C Mefford;Andrew J Sharp;Carl Baker;Andy Itsara.
The New England Journal of Medicine (2008)

730 Citations

Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome

Andrew J Sharp;Sierra Hansen;Rebecca R Selzer;Ze Cheng.
Nature Genetics (2006)

637 Citations

15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

Ingo Helbig;Heather C. Mefford;Andrew J. Sharp;Michel Guipponi.
Nature Genetics (2009)

602 Citations

A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures.

Andrew J Sharp;Heather C Mefford;Kelly Li;Carl Baker.
Nature Genetics (2008)

585 Citations

Linkage Disequilibrium and Heritability of Copy-Number Polymorphisms within Duplicated Regions of the Human Genome

Devin P. Locke;Andrew J. Sharp;Steven A. McCarroll;Steven A. McCarroll;Sean D. McGrath.
American Journal of Human Genetics (2006)

376 Citations

Age- and tissue-specific variation of X chromosome inactivation ratios in normal women.

Andrew Sharp;David Robinson;Patricia Jacobs.
Human Genetics (2000)

362 Citations

Structural Variation of the Human Genome

Andrew J. Sharp;Ze Cheng;Evan E. Eichler.
Annual Review of Genomics and Human Genetics (2006)

295 Citations

DNA methylation profiles of human active and inactive X chromosomes

Andrew J. Sharp;Elisavet Stathaki;Eugenia Migliavacca;Manisha Brahmachary.
Genome Research (2011)

273 Citations

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