Alfred E. Chang

Best Publications

• A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone.

  Steven A. Rosenberg;Michael T. Lotze;Linda M. Muul;Alfred E. Chang

  3636
  Citations

• Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer

  Steven A. Rosenberg;Michael T. Lotze;Linda M. Muul;Susan Leitman

  3429
  Citations

• Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans

  Gary J. Nabel;Elizabeth G. Nabel;Zhi Yong Yang;Bernard A. Fox

  1246
  Citations

• Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

  Ilona Kryczek;Mousumi Banerjee;Pui Cheng;Linhua Vatan

  1005
  Citations

• Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study.

  S L Topalian;D Solomon;F P Avis;A E Chang

  616
  Citations

• Cutting Edge: Th17 and Regulatory T Cell Dynamics and the Regulation by IL-2 in the Tumor Microenvironment

  Ilona Kryczek;Shuang Wei;Linhua Zou;Saleh Altuwaijri

  575
  Citations

• Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis.

  Christina M. Coughlin;Kevin E. Salhany;Maria Wysocka;Etsuko Aruga

  538
  Citations

• Vaccination Of Pediatric Solid Tumor Patients with Tumor Lysate-pulsed Dendritic Cells Can Expand Specific T Cells and Mediate Tumor Regression

  James D. Geiger;Raymond J. Hutchinson;Lyndon F. Hohenkirk;Elizabeth A. McKenna

  413
  Citations

• Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA–liposome complexes

  Gary J. Nabel;David Gordon;D. Keith Bishop;Brian J. Nickoloff

  338
  Citations

• IL-17+ Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer

  Ilona Kryczek;Ke Wu;Ende Zhao;Shuang Wei

  322
  Citations

• Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2.

  Hirohisa Yoshizawa;Alfred E. Chang;Suyu Shu

  310
  Citations

• Cancer stem cell vaccination confers significant antitumor immunity

  Ning Ning;Qin Pan;Qin Pan;Fang Zheng;Fang Zheng;Seagal Teitz-Tennenbaum

  293
  Citations

• A Phase I Trial of Tumor Lysate-pulsed Dendritic Cells in the Treatment of Advanced Cancer

  Alfred E. Chang;Bruce G. Redman;Joel R. Whitfield;Brian J. Nickoloff

  282
  Citations

• Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling

  Dongjun Peng;Takashi Tanikawa;Wei Li;Lili Zhao

  270
  Citations

• Immunologic response to cryoablation of breast cancer

  Michael S. Sabel;Matthew A. Nehs;Gang Su;Kathleen P. Lowler

  237
  Citations

• Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2.

  A E Chang;A Aruga;M J Cameron;V K Sondak

  235
  Citations

• Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration.

  Seagal Teitz-Tennenbaum;Qiao Li;Susan Rynkiewicz;Fumito Ito

  233
  Citations

• Current Status and Future Directions

  Unknown

  226
  Citations

• The impact of factors beyond Breslow depth on predicting sentinel lymph node positivity in melanoma.

  Sandra C. Paek;Kent A. Griffith;Timothy M. Johnson;Vernon K. Sondak

  224
  Citations

• FOXP3 defines regulatory T cells in human tumor and autoimmune disease

  Ilona Kryczek;Rebecca Liu;Guobin Wang;Ke Wu

  219
  Citations