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Chemistry

D-Index
53
Citations
8665
World Ranking
13218
National Ranking
528

Overview

Alain Brunelle is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their work spans the fields of Chemistry and Arts and Humanities, focusing primarily on interdisciplinary approaches that integrate chemical analysis with cultural heritage studies.

Their research covers several subfields including Archeology, Computational Mechanics, Analytical Chemistry, Inorganic Chemistry, and Molecular Biology. These areas reflect a broad interest in both the scientific and applied aspects of material analysis and heritage conservation.

Brunelle's main research topics include:

  • Cultural Heritage Materials Analysis
  • Ion-surface interactions and analysis
  • Pigment Synthesis and Properties
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Conservation Techniques and Studies
  • Mass Spectrometry Techniques and Applications
  • Metabolomics and Mass Spectrometry Studies

Their publication record demonstrates a focus on analytical techniques and applications to both biological tissues and cultural heritage objects. Frequent publication venues include:

  • Surface Science Spectra
  • Analytical Chemistry
  • Journal of Mass Spectrometry
  • Journal of Cultural Heritage
  • Methods in Molecular Biology

Brunelle has collaborated extensively with several researchers, including:

  • Caroline Bouvier
  • Sebastiaan Van Nuffel
  • Aline Cournut
  • Philippe Walter
  • David Touboul

Some of the notable recent papers authored or co-authored by Alain Brunelle are:

  • "Multimodal Imaging Based on Vibrational Spectroscopies and Mass Spectrometry Imaging Applied to Biological Tissue: A Multiscale and Multiomics Review" (2020, Analytical Chemistry)
  • "Multimodal Imaging Mass Spectrometry to Identify Markers of Pulmonary Arterial Hypertension in Human Lung Tissue Using MALDI-ToF, ToF-SIMS, and Hybrid SIMS" (2020, Analytical Chemistry)
  • "Time-of-flight secondary ion mass spectrometry imaging in cultural heritage: A focus on old paintings" (2021, Journal of Mass Spectrometry)
  • "Wax finishing in Roman polychrome statuary: Ganosis on the colossal head from Dougga (Tunisia)" (2021, Journal of Cultural Heritage)
  • "Time-of-Flight Secondary Ion Mass Spectrometry Imaging of Cross Sections from the Bacchanals Paintings of Nicolas Poussin" (2021, Analytical Chemistry)

Best Publications

  • Improvement of biological time-of-flight-secondary ion mass spectrometry imaging with a bismuth cluster ion source.

    David Touboul;Felix Kollmer;Ewald Niehuis;Alain Brunelle

  • imzML--a common data format for the flexible exchange and processing of mass spectrometry imaging data.

    Thorsten Schramm;Alfons Hester;Ivo Klinkert;Jean-Pierre Both

  • Tissue Molecular Ion Imaging by Gold Cluster Ion Bombardment

    David Touboul;Fréderic Halgand;Alain Brunelle;Reinhard Kersting

  • Biological tissue imaging with time-of-flight secondary ion mass spectrometry and cluster ion sources

    Alain Brunelle;David Touboul;Olivier Laprévote

  • Impact of slow gold clusters on various solids: nonlinear effects in secondary ion emission

    M. Benguerba;A. Brunelle;S. Della-Negra;J. Depauw

  • Abiotic synthesis of amino acids in the recesses of the oceanic lithosphere.

    Bénédicte Ménez;Céline Pisapia;Céline Pisapia;Muriel Andreani;Frédéric Jamme

  • Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

    Franck Chiappini;Audrey Coilly;Hanane Kadar;Philippe Gual;Philippe Gual

  • Impact of rhizosphere factors on cyclic lipopeptide signature from the plant beneficial strain Bacillus amyloliquefaciens S499

    Venant Nihorimbere;Hélène Cawoy;Alexandre Seyer;Alain Brunelle

  • Tracks in metals by MeV fullerenes.

    H. Dammak;A. Dunlop;D. Lesueur;A. Brunelle

  • In situ lipidomic analysis of nonalcoholic fatty liver by cluster TOF-SIMS imaging.

    Delphine Debois;Marie-Pierre Bralet;François Le Naour;Alain Brunelle

  • GIANT METAL SPUTTERING YIELDS INDUCED BY 20-5000 KEV/ATOM GOLD CLUSTERS

    H. H. Andersen;A. Brunelle;S. Della-Negra;J. Depauw

  • MALDI imaging and structural analysis of rat brain lipid negative ions with 9-aminoacridine matrix.

    Christopher D Cerruti;Farida Benabdellah;Olivier Laprévote;Olivier Laprévote;David Touboul

  • Lipid imaging by gold cluster time-of-flight secondary ion mass spectrometry : application to Duchenne muscular dystrophy

    David Touboul;Alain Brunelle;Frédéric Halgand;Sabine De La Porte

  • Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients

    Adina N. Lazar;Claudia Bich;Maï Panchal;Nicolas Desbenoit

  • Changes of phospholipid composition within the dystrophic muscle by matrix-assisted laser desorption/ionization mass spectrometry and mass spectrometry imaging.

    David Touboul;Hélène Piednoël;Vincent Voisin;Sabine De La Porte

  • Mass spectrometry imaging of rat brain sections: nanomolar sensitivity with MALDI versus nanometer resolution by TOF–SIMS

    Farida Benabdellah;Alexandre Seyer;Loïc Quinton;David Touboul

  • Energy loss by MeV carbon clusters and fullerene ions in solids

    K. Baudin;A. Brunelle;M. Chabot;S. Della-Negra

  • A New Safety Concern for Glaucoma Treatment Demonstrated by Mass Spectrometry Imaging of Benzalkonium Chloride Distribution in the Eye, an Experimental Study in Rabbits

    Françoise Brignole-Baudouin;Nicolas Desbenoit;Gregory Hamm;Hong Liang

  • Enhanced secondary-ion emission under gold-cluster bombardment with energies from keV to MeV per atom

    A. Brunelle;S. della-Negra;J. Depauw;D. Jacquet

  • MALDI-TOF and cluster-TOF-SIMS imaging of Fabry disease biomarkers

    David Touboul;Sandrine Roy;Dominique P. Germain;Pierre Chaminade

  • Lipid imaging with cluster time-of-flight secondary ion mass spectrometry

    Alain Brunelle;Olivier Laprévote

Frequent Co-Authors

Olivier Laprévote
Olivier Laprévote Université Paris Cité
Christophe Baudouin
Christophe Baudouin Institut de la Vision
Ron M. A. Heeren
Ron M. A. Heeren Maastricht University
Bernhard Spengler
Bernhard Spengler University of Giessen
Gilles Flamant
Gilles Flamant Centre national de la recherche scientifique, CNRS
Jean-Pierre Cuif
Jean-Pierre Cuif University of Paris-Saclay
Patrick Bernier
Patrick Bernier University of Montpellier
Yannicke Dauphin
Yannicke Dauphin Sorbonne University
Aleksander Edelman
Aleksander Edelman Université Paris Cité
Pieter C. Dorrestein
Pieter C. Dorrestein University of California, San Diego

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