World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
8772
World Ranking
18675
National Ranking
7635

Overview

Timothy F. Kowalik is affiliated with the University of Massachusetts Chan Medical School in the United States. The primary focus of their research spans the field of medicine with specialized contributions to epidemiology, infectious diseases, molecular biology, public health, environmental and occupational health, and virology.

The scientist's work covers several main topics, including:

  • Cytomegalovirus and herpesvirus research
  • Herpesvirus infections and treatments
  • Parvovirus B19 infection studies
  • SARS-CoV-2 and COVID-19 research
  • Viral gastroenteritis research and epidemiology
  • HIV research and treatment
  • Evolution and genetic dynamics

Timothy F. Kowalik has collaborated frequently with several researchers in the field. Their notable coauthors include:

  • Anne M. Mirza
  • Amitinder Kaur
  • Daniel Malouli
  • Jeffrey D. Jensen
  • Sallie R. Permar

The scientist has published in a range of venues. The most frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • PLoS Pathogens
  • Journal of Virology
  • Viruses

Recent papers by Timothy F. Kowalik include:

  • In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome, 2020, PLoS Pathogens
  • Common Polymorphisms in the Glycoproteins of Human Cytomegalovirus and Associated Strain-Specific Immunity, 2021, Viruses
  • Imposed mutational meltdown as an antiviral strategy, 2020, Evolution
  • Virology under the Microscope-a Call for Rational Discourse, 2023, Journal of Virology
  • Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection, 2023, PLoS Pathogens

Best Publications

  • Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes.

    James DeGregori;Timothy Kowalik;Joseph R. Nevins

  • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

    Timothy F. Kowalik;James DeGregori;James K. Schwarz;Joseph R. Nevins

  • Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

    George Savidis;William M. McDougall;Paul Meraner;Jill M. Perreira

  • HUMAN CYTOMEGALOVIRUS UPREGULATES NF-KAPPA B ACTIVITY BY TRANSACTIVATING THE NF-KAPPA B P105/P50 AND P65 PROMOTERS

    A. D. Yurochko;T. F. Kowalik;Shu-Mei Huong;Eng-Shang Huang

  • Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants

    Nicholas Renzette;Bornali Bhattacharjee;Jeffrey D. Jensen;Laura L. Gibson

  • E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2

    TF Kowalik;J DeGregori;G Leone;L Jakoi

  • Multiple mechanisms are implicated in the regulation of NF-kappa B activity during human cytomegalovirus infection.

    T. F. Kowalik;Bret Wing;J. S. Haskill;J. C. Azizkhan

  • Human cytomegalovirus immediate early proteins and cell growth control

    Jonathan Patrick Castillo;Timothy F. Kowalik

  • miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression.

    Mary Theresa Pickering;Bradford Michael Stadler;Timothy F. Kowalik

  • Antiviral drug resistance as an adaptive process

    Kristen K. Irwin;Kristen K. Irwin;Nicholas Renzette;Timothy F. Kowalik;Jeffrey D. Jensen;Jeffrey D. Jensen

  • Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3).

    Colin S. Duckett;Neil D. Perkins;Timothy F. Kowalik;Roland M. Schmid

  • The viral oncoprotein E1A blocks transforming growth factor beta-mediated induction of p21/WAF1/Cip1 and p15/INK4B.

    M B Datto;P P Hu;T F Kowalik;J Yingling

  • Role of Human Cytomegalovirus Immediate-Early Proteins in Cell Growth Control

    Jonathan Patrick Castillo;Andrew D. Yurochko;Timothy F. Kowalik

  • Rapid Intrahost Evolution of Human Cytomegalovirus Is Shaped by Demography and Positive Selection

    Nicholas Renzette;Laura L. Gibson;Bornali Bhattacharjee;Donna Fisher

  • E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection.

    Michael Wade;Timothy F. Kowalik;Maria Mudryj;Eng Shang Huang

  • Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2.

    Harry A. Rogoff;Mary T. Pickering;Fiona M. Frame;Michelle E. Debatis

  • The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter.

    Eric E. Poma;Timothy F. Kowalik;Liang Zhu;John H. Sinclair

  • Inhibition of the ATM/p53 Signal Transduction Pathway by Kaposi's Sarcoma-Associated Herpesvirus Interferon Regulatory Factor 1

    Young C. Shin;Hiroyuki Nakamura;Xiaozhen Liang;Pinghui Feng

  • E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis

    Harry A. Rogoff;Mary Theresa Pickering;Michelle E. Debatis;Stephen N. Jones

  • Influenza virus drug resistance: A time-sampled population genetics perspective

    Matthieu Foll;Yu Ping Poh;Nicholas Renzette;Anna Ferrer-Admetlla

Frequent Co-Authors

Jeffrey D. Jensen
Jeffrey D. Jensen Arizona State University
Robert W. Finberg
Robert W. Finberg University of Massachusetts Chan Medical School
Celia A. Schiffer
Celia A. Schiffer University of Massachusetts Chan Medical School
Eng-Shang Huang
Eng-Shang Huang University of North Carolina at Chapel Hill
Robert J. Porte
Robert J. Porte University Medical Center Groningen
Jae U. Jung
Jae U. Jung Cleveland Clinic
Mark R. Schleiss
Mark R. Schleiss University of Minnesota
James DeGregori
James DeGregori University of Colorado Anschutz Medical Campus
William J. Britt
William J. Britt University of Alabama at Birmingham
Wayne A. Marasco
Wayne A. Marasco Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry opens the door to a variety of career options, many of which now offer flexible online learning formats. Students interested in pharmaceuticals may consider pharm d online programs to earn a Doctor of Pharmacy degree and prepare for licensure as a pharmacist.

For those drawn to fitness, wellness, or athletic performance, an exercise science and nutrition degree online provides focused knowledge on how biology and biochemistry fuel human health and movement. Similarly, online kinesiology programs offer specialized training in body mechanics, rehabilitation, and sports science.

If your interests intersect with mental health, accelerated clinical pathways such as the fastest post master's pmhnp programs enable nurses to quickly gain credentials as Psychiatric Mental Health Nurse Practitioners. These diverse online degrees offer both flexibility and targeted expertise, helping you shape a meaningful science-based career.

Best Scientists Citing Timothy F. Kowalik

Trending Scientists