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Biology and Biochemistry

D-Index
63
Citations
12748
World Ranking
10329
National Ranking
747

Overview

Thomas Pap is a researcher affiliated with the University of Münster in Germany, with a significant academic output primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work encompasses multiple subfields including Molecular Biology, Rheumatology, Immunology, Immunology and Allergy, and Cell Biology.

Their research contributions focus on key topics such as:

  • Osteoarthritis Treatment and Mechanisms
  • Cell Adhesion Molecules Research
  • Rheumatoid Arthritis Research and Therapies
  • Cellular Mechanics and Interactions
  • Protease and Inhibitor Mechanisms
  • Proteoglycans and glycosaminoglycans research
  • Bone Metabolism and Diseases

Thomas Pap has published extensively in respected journals, with frequent contributions to:

  • Annals of the Rheumatic Diseases
  • Osteoarthritis and Cartilage
  • Nature Communications
  • Scientific Reports
  • Cell Death and Disease

Among the recent papers featuring Pap as an author are:

  • "Synovial fibroblasts and articular tissue remodelling: Role and mechanisms," 2020, Seminars in Cell and Developmental Biology

Other notable papers relevant to this research area include:

  • "Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9-mediated genome editing events," 2020, Science Advances
  • "Synovial fibroblasts as potential drug targets in rheumatoid arthritis, where do we stand and where shall we go?", 2022, Annals of the Rheumatic Diseases
  • "Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis," 2020, Annals of the Rheumatic Diseases
  • "BCP crystals promote chondrocyte hypertrophic differentiation in OA cartilage by sequestering Wnt3a," 2020, Annals of the Rheumatic Diseases

Thomas Pap has collaborated with several frequent co-authors, including Adelheid Korb-Pap, J. Sherwood, Jessica Bertrand, Denise Beckmann, and Berno Dankbar, indicating a network of joint research activities focused on similar biomedical topics.

Best Publications

  • Synovial fibroblasts: key players in rheumatoid arthritis

    L. C. Huber;O. Distler;I. Tarner

  • Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

    Stephanie Lefèvre;Anette Knedla;Christoph Tennie;Andreas Kampmann

  • TNF-induced structural joint damage is mediated by IL-1

    Jochen Zwerina;Kurt Redlich;Karin Polzer;Leo Joosten

  • Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis

    Frank Echtermeyer;Jessica Bertrand;Rita Dreier;Ingmar Meinecke

  • Calcification of articular cartilage in human osteoarthritis

    M. Fuerst;J. Bertrand;L. Lammers;R. Dreier

  • Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

    Marc C. Hochberg;Johanne Martel-Pelletier;Jordi Monfort;Ingrid Möller

  • Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts

    Ulf Müller-Ladner;Caroline Ospelt;Oliver Distler

  • Estrogen-dependent and C-C chemokine receptor-2–dependent pathways determine osteoclast behavior in osteoporosis

    Nikolaus B Binder;Birgit Niederreiter;Oskar Hoffmann;Richard Stange

  • WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways

    Giovanna Nalesso;Joanna Sherwood;Jessica Bertrand;Thomas Pap

  • Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis.

    Oliver Distler;Thomas Pap;Otylia Kowal‐Bielecka;Rotraud Meyringer

  • Cell death in rheumatoid arthritis.

    Adelheid Korb;Hermann Pavenstädt;Thomas Pap

  • Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation

    Thomas Vogl;Athanasios Stratis;Viktor Wixler;Tom Völler

  • Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts

    Ingmar Meinecke;Antje Cinski;Anja Baier;Marvin A. Peters

  • Cartilage biology, pathology, and repair

    Daniel Umlauf;Svetlana Frank;Thomas Pap;Jessica Bertrand

  • Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3.

    W H van der Laan;P H A Quax;C A Seemayer;L G M Huisman

  • Interleukin-16, produced by synovial fibroblasts, mediates chemoattraction for CD4 + T lymphocytes in rheumatoid arthritis

    Juliane K. Franz;Stefan A. Kolb;Klaus M. Hummel;Fritz Lahrtz

  • Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

    Corinna Wehmeyer;Svetlana Frank;Denise Beckmann;Martin Böttcher

  • Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

    Kerstin Göbel;Susann Pankratz;Chloi-Magdalini Asaridou;Alexander M. Herrmann

  • Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis

    Adelheid Korb-Pap;Athanasios Stratis;Katja Mühlenberg;Birgit Niederreiter

  • Intravenous immunoglobulins and transforming growth factor β

    Jörn Kekow;Dirk Reinhold;Thomas Pap;Siegfried Ansorge

Frequent Co-Authors

George Kollias
George Kollias National and Kapodistrian University of Athens
Nigel K. Arden
Nigel K. Arden University of Oxford
Francis Berenbaum
Francis Berenbaum Université Paris Cité
Ulf Müller-Ladner
Ulf Müller-Ladner University of Giessen
Thomas Kamradt
Thomas Kamradt Friedrich Schiller University Jena
Dietmar Vestweber
Dietmar Vestweber Max Planck Society
Josef S. Smolen
Josef S. Smolen Medical University of Vienna
Marc C. Hochberg
Marc C. Hochberg University of Maryland, Baltimore
Hermann Pavenstädt
Hermann Pavenstädt University of Freiburg
Yves Henrotin
Yves Henrotin University of Liège

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