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Biology and Biochemistry

D-Index
59
Citations
12251
World Ranking
12554
National Ranking
5370

Overview

Shyni Varghese is affiliated with Duke University in the United States, with a primary focus spanning medicine and biochemistry, genetics, and molecular biology. Their work encompasses multiple subfields, including biomedical engineering, molecular biology, surgery, physiology, and rheumatology.

Varghese's research covers diverse topics predominantly within biomedical research and regenerative medicine. Key topics include:

  • 3D Printing in Biomedical Research
  • Osteoarthritis Treatment and Mechanisms
  • Adenosine and Purinergic Signaling
  • Tissue Engineering and Regenerative Medicine
  • Soft Robotics and Applications
  • Knee Injuries and Reconstruction Techniques
  • Micro and Nano Robotics

The scientist has published extensively with frequent contributions to several journals and venues. Principal publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Advanced Functional Materials
  • Biomaterials Science
  • Biomaterials
  • Advanced Healthcare Materials

Recent scholarly articles authored or coauthored by Varghese highlight significant research areas and are listed below with their publication year and venues:

  • Resolution of inflammation in bone regeneration: From understandings to therapeutic applications, 2021, Biomaterials
  • Rationally Designed Anisotropic and Auxetic Hydrogel Patches for Adaptation to Dynamic Organs, 2022, Advanced Functional Materials
  • Bone targeting nanocarrier-assisted delivery of adenosine to combat osteoporotic bone loss, 2021, Biomaterials
  • Protective effects of omega-3 fatty acids in a blood-brain barrier-on-chip model and on postoperative delirium-like behaviour in mice, 2022, British Journal of Anaesthesia
  • Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer, 2023, Nature Communications

Varghese collaborates regularly with a core group of fellow researchers, including Jiaul Hoque, Hunter Newman, Vardhman Kumar, Yu-Ru V. Shih, and Anna Gilpin. These frequent coauthors suggest a network of interdisciplinary cooperation enhancing the scope of their work.

Best Publications

  • Multifunctional chondroitin sulphate for cartilage tissue-biomaterial integration.

    Dong An Wang;Dong An Wang;Shyni Varghese;Blanka Sharma;Iossif Strehin

  • Rapid self-healing hydrogels.

    Ameya Phadke;Chao Zhang;Bedri Arman;Cheng-Chih Hsu

  • Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells.

    Shyni Varghese;Nathaniel S. Hwang;Adam C. Canver;Parnduangji Theprungsirikul

  • Controlled differentiation of stem cells.

    Nathaniel S. Hwang;Shyni Varghese;Jennifer Elisseeff

  • Engineering the cell–material interface for controlling stem cell adhesion, migration, and differentiation

    Ramses Ayala;Chao Zhang;Darren Yang;Yongsung Hwang

  • Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling

    Yu Ru V. Shih;Yu Ru V. Shih;Yongsung Hwang;Ameya Phadke;Heemin Kang

  • In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells

    Nathaniel S. Hwang;Shyni Varghese;Shyni Varghese;H. Janice Lee;Zijun Zhang;Zijun Zhang

  • Chondrogenic Differentiation of Human Embryonic Stem Cell–Derived Cells in Arginine-Glycine-Aspartate–Modified Hydrogels

    Nathaniel S. Hwang;Shyni Varghese;Zijun Zhang;Jennifer Elisseeff

  • PEG/clay nanocomposite hydrogel: a mechanically robust tissue engineering scaffold

    CW Chang;Acc Ariane van Spreeuwel;C Chunzhou Zhang;S Varghese

  • Cartilage-like mechanical properties of poly (ethylene glycol)-diacrylate hydrogels.

    Quynhhoa T. Nguyen;Yongsung Hwang;Albert C. Chen;Shyni Varghese

  • Smart hydrogels as functional biomimetic systems

    Han L. Lim;Yongsung Hwang;Mrityunjoy Kar;Shyni Varghese

  • Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces

    David A. Brafman;Chien W. Chang;Antonio Fernandez;Karl Willert

  • Hydrogels for musculoskeletal tissue engineering

    Shyni Varghese;Jennifer H. Elisseeff

  • Influence of Physical Properties of Biomaterials on Cellular Behavior

    Susan Lin;Nivedita Sangaj;Tojo Razafiarison;Chao Zhang

  • Mesenchymal stem cell differentiation and roles in regenerative medicine

    Nathaniel S. Hwang;Chao Zhang;Yong-Sung Hwang;Shyni Varghese

  • Method for Decellularizing Skeletal Muscle Without Detergents or Proteolytic Enzymes

    Allison R. Gillies;Lucas R. Smith;Richard L. Lieber;Shyni Varghese

  • Morphogenetic signals from chondrocytes promote chondrogenic and osteogenic differentiation of mesenchymal stem cells

    Nathaniel S. Hwang;Shyni Varghese;Christopher Puleo;Zijun Zhang

  • In vivo RNA editing of point mutations via RNA-guided adenosine deaminases.

    Dhruva Katrekar;Genghao Chen;Dario Meluzzi;Ashwin Ganesh

  • Skeletal muscle-on-a-chip: an in vitro model to evaluate tissue formation and injury

    Gaurav Agrawal;Aereas Aung;Shyni Varghese

  • Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression

    S. Varghese;P. Theprungsirikul;S. Sahani;N. Hwang

Frequent Co-Authors

Jennifer H. Elisseeff
Jennifer H. Elisseeff Johns Hopkins University
Nathaniel S. Hwang
Nathaniel S. Hwang Seoul National University
Shu Chien
Shu Chien University of California, San Diego
Kang Zhang
Kang Zhang Macau University of Science and Technology
Shaochen Chen
Shaochen Chen University of California, San Diego
Prashant Mali
Prashant Mali University of California, San Diego
Dong-An Wang
Dong-An Wang City University of Hong Kong
Stefan Zauscher
Stefan Zauscher Duke University
Kenneth S. Vecchio
Kenneth S. Vecchio University of California, San Diego
Oscar K. Lee
Oscar K. Lee National Yang Ming University

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