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Sergey N. Krylov

Sergey N. Krylov

D-Index & Metrics

Chemistry

D-Index
49
Citations
8599
World Ranking
14817
National Ranking
403

Overview

Sergey N. Krylov is affiliated with York University in Canada, focusing on research that intersects engineering and biochemistry, genetics, and molecular biology. Their work spans both fundamental and applied sciences within these domains, with a significant presence in biomedical engineering and molecular biology subfields.

The scientist's research covers topics related to microfluidic and capillary electrophoresis applications, biosensors and analytical detection methods, as well as advanced biosensing and bioanalysis techniques. Additional areas of interest include microfluidic and bio-sensing technologies, innovative microfluidic and catalytic techniques, computational drug discovery methods, and thermodynamics with calorimetric analyses.

Sergey N. Krylov has contributed to multiple papers, some of the recent works include:

  • Electrophoresis-Assisted Multilayer Assembly of Nanoparticles for Sensitive Lateral Flow Immunoassay (2022, Angewandte Chemie International Edition)
  • How to Develop and Prove High-Efficiency Selection of Ligands from Oligonucleotide Libraries: A Universal Framework for Aptamers and DNA-Encoded Small-Molecule Ligands (2021, Analytical Chemistry)
  • Electrophoretic Assembly of Antibody-Antigen Complexes Facilitates 1000 Times Improvement in the Limit of Detection of Serological Paper-Based Assay (2023, ACS Sensors)
  • Fundamental Determinants of the Accuracy of Equilibrium Constants for Affinity Complexes (2023, Analytical Chemistry)
  • Maximizing the Accuracy of Equilibrium Dissociation Constants for Affinity Complexes: From Theory to Practical Recommendations (2024, ACS Chemical Biology)

The recurring venues for Sergey N. Krylov's publications include:

  • Analytical Chemistry
  • ChemBioChem
  • Preprints.org
  • Angewandte Chemie International Edition
  • Russian Journal of Cardiology

Frequent collaborators in their research include Svetlana M. Krylova, Tong Ye Wang, Nikita A. Ivanov, An T. H. Le, and Sven Kochmann. These partnerships represent a core network supporting interdisciplinary approaches, contributing to the depth and breadth of their scientific output.

The integration of biotechnology and engineering is evident in Sergey N. Krylov's focus areas such as microfluidics, biosensors, and affinity complex analysis. This blend facilitates investigations into novel diagnostic platforms and quantitative analytical methods, aligning closely with broader trends in biomedical engineering and chemical biology.

Best Publications

  • Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures: A Universal Tool for Development of Aptamers

    Maxim Berezovski;Andrei Drabovich;Svetlana M. Krylova;Michael Musheev

  • Non-SELEX Selection of Aptamers

    Maxim Berezovski;Michael Musheev;and Andrei Drabovich;Sergey N. Krylov

  • Aptamer-Facilitated Biomarker Discovery (AptaBiD)

    Maxim V. Berezovski;Matthias Lechmann;Michael U. Musheev;Tak W. Mak

  • Nonequilibrium capillary electrophoresis of equilibrium mixtures--a single experiment reveals equilibrium and kinetic parameters of protein-DNA interactions.

    Maxim Berezovski;Sergey N. Krylov

  • Selection of smart aptamers by equilibrium capillary electrophoresis of equilibrium mixtures (ECEEM).

    Andrei Drabovich;Maxim Berezovski;Sergey N. Krylov

  • Selection of smart aptamers by methods of kinetic capillary electrophoresis.

    Andrei P. Drabovich;Maxim Berezovski;Victor Okhonin;Sergey N. Krylov

  • Affinity Analysis of a Protein−Aptamer Complex Using Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures

    Maxim Berezovski;Razvan Nutiu;Yingfu Li;Sergey N. Krylov

  • Capillary Electrophoresis for the Analysis of Biopolymers

    Sergey N. Krylov;Norman J. Dovichi

  • Kinetic Capillary Electrophoresis (KCE): A Conceptual Platform for Kinetic Homogeneous Affinity Methods

    Alexander Petrov;Victor Okhonin;Maxim Berezovski;Sergey N. Krylov

  • Instrumentation for chemical cytometry.

    Sergey N. Krylov;Dieter A. Starke;Edgar A. Arriaga;Zheru Zhang

  • Selection of aptamers by systematic evolution of ligands by exponential enrichment: addressing the polymerase chain reaction issue.

    Michael U. Musheev;Sergey N. Krylov

  • Kinetic CE: Foundation for homogeneous kinetic affinity methods

    Sergey N. Krylov

  • Synthetic, Switchable Enzymes

    Vic Norris;Sergey N. Krylov;Pratul K. Agarwal;Glenn J. White

  • One-dimensional protein analysis of an HT29 human colon adenocarcinoma cell.

    Zheru Zhang;Sergey Krylov;Edgar A. Arriaga;Robert Polakowski

  • Correlating cell cycle with metabolism in single cells: Combination of image and metabolic cytometry

    Sergey N. Krylov;Zheru Zhang;Nora W.C. Chan;Edgar Arriaga

  • Reversible photocontrol of DNA binding by a designed GCN4-bZIP protein.

    G. Andrew Woolley;Anna S. I. Jaikaran;Maxim Berezovski;Joseph P. Calarco

  • Mechanistic quantitative structure–activity relationship model for the photoinduced toxicity of polycyclic aromatic hydrocarbons: I. Physical model based on chemical kinetics in a two-compartment system

    Sergey N. Krylov;Xiao-Dong Huang;Lorelei F. Zeiler;D. George Dixon

  • Capillary Electrophoresis for Quantitative Studies of Biomolecular Interactions

    Victor A. Galievsky;Alexander S. Stasheuski;Sergey N. Krylov

  • AID Associates with Single-Stranded DNA with High Affinity and a Long Complex Half-Life in a Sequence-Independent Manner

    Mani Larijani;Alexander P. Petrov;Oxana Kolenchenko;Maribel Berru

  • Tau protein binds single-stranded DNA sequence specifically--the proof obtained in vitro with non-equilibrium capillary electrophoresis of equilibrium mixtures.

    Svetlana M. Krylova;Michael Musheev;Razvan Nutiu;Yingfu Li

Frequent Co-Authors

George M. Yousef
George M. Yousef University of Toronto
Norman J. Dovichi
Norman J. Dovichi University of Notre Dame
Chun Peng
Chun Peng York University
Geoffrey Liu
Geoffrey Liu Princess Margaret Cancer Centre
Burton B. Yang
Burton B. Yang University of Toronto
Edgar A. Arriaga
Edgar A. Arriaga University of Minnesota
Christopher J. Schofield
Christopher J. Schofield University of Oxford
Andreas Scorilas
Andreas Scorilas National and Kapodistrian University of Athens
Monica M. Palcic
Monica M. Palcic Carlsberg Laboratory
Michael A.S. Jewett
Michael A.S. Jewett University of Toronto

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