World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
20827
World Ranking
8996
National Ranking
3997

Research.com Recognitions

  • 1972 - Fellow of Alfred P. Sloan Foundation

Overview

Sanford M. Simon is affiliated with Rockefeller University in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans multiple subfields including molecular biology, cancer research, hepatology, cell biology, and radiology, nuclear medicine, and imaging.

Their work covers several main topics, among which are:

  • Cancer Genomics and Diagnostics
  • Ubiquitin and Proteasome Pathways
  • Cancer, Hypoxia, and Metabolism
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Protein Degradation and Inhibitors
  • RNA Research and Splicing
  • Liver Physiology and Pathology

Sanford M. Simon has authored numerous publications in prominent venues. Frequent publication venues include:

  • Cancer Research (16 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • Nature Communications (2 publications)
  • Cancers (2 publications)
  • Communications Biology (2 publications)

Recent papers authored or co-authored by Sanford M. Simon cover a range of topics primarily related to cellular biology and cancer. Notable publications include:

  • "Stem cell-derived polarized hepatocytes," 2020, Nature Communications
  • "A Human Organoid Model of Aggressive Hepatoblastoma for Disease Modeling and Drug Testing," 2020, Cancers
  • "Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening," 2021, Cancer Discovery
  • "Clinical Outcomes in Fibrolamellar Hepatocellular Carcinoma Treated with Immune Checkpoint Inhibitors," 2022, Cancers
  • "Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A," 2021, Communications Biology

Sanford M. Simon has collaborated frequently with several researchers, including:

  • Philip Coffino
  • David Requena
  • Denise Ng
  • Mahsa Shirani
  • Bassem Shebl

In 1972, Sanford M. Simon was recognized as a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • Long-term multiple color imaging of live cells using quantum dot bioconjugates

    Jyoti K. Jaiswal;Hedi Mattoussi;J. Matthew Mauro;Sanford M. Simon

  • Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy.

    Evelyn B Voura;Jyoti K Jaiswal;Hedi Mattoussi;Sanford M Simon

  • A protein-conducting channel in the endoplasmic reticulum.

    Sanford M. Simon;Giinter Blobel

  • Synthesis of compact multidentate ligands to prepare stable hydrophilic quantum dot fluorophores.

    H Tetsuo Uyeda;Igor L Medintz;Jyoti K Jaiswal;Sanford M Simon

  • Potentials and pitfalls of fluorescent quantum dots for biological imaging

    Jyoti K. Jaiswal;Sanford M. Simon

  • Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release

    S.M. Simon;R.R. Llinás

  • Cell biological mechanisms of multidrug resistance in tumors

    Sanford M. Simon;Melvin Schindler

  • What drives the translocation of proteins

    S M Simon;C S Peskin;G F Oster

  • Detection of a Recurrent DNAJB1-PRKACA Chimeric Transcript in Fibrolamellar Hepatocellular Carcinoma

    Joshua N. Honeyman;Joshua N. Honeyman;Elana P. Simon;Nicolas Robine;Rachel Chiaroni-Clarke

  • Imaging with total internal reflection fluorescence microscopy for the cell biologist.

    Alexa L. Mattheyses;Sanford M. Simon;Joshua Z. Rappoport

  • Use of quantum dots for live cell imaging

    Jyoti K Jaiswal;Ellen R Goldman;Hedi Mattoussi;Sanford M Simon

  • Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells

    Jyoti K. Jaiswal;Norma W. Andrews;Sanford M. Simon

  • Imaging the biogenesis of individual HIV-1 virions in live cells

    Nolwenn Jouvenet;Paul D. Bieniasz;Sanford M. Simon

  • Plasma membrane is the site of productive HIV-1 particle assembly.

    Nolwenn Jouvenet;Stuart J. D Neil;Stuart J. D Neil;Cameron Bess;Marc C Johnson

  • Defective acidification in human breast tumor cells and implications for chemotherapy.

    Nihal Altan;Yu Chen;Melvin Schindler;Sanford M. Simon

  • Intracellular pH and the control of multidrug resistance

    Sanford Simon;Deborshi Roy;Melvin Schindler

  • Imaging the interaction of HIV-1 genomes and Gag during assembly of individual viral particles

    Nolwenn Jouvenet;Sanford M. Simon;Paul D. Bieniasz

  • Defective pH Regulation of Acidic Compartments in Human Breast Cancer Cells (MCF-7) Is Normalized in Adriamycin-Resistant Cells (MCF-7adr)†

    Melvin Schindler;Sharon Grabski;Ed Hoff;Sanford M. Simon

  • Tracking single proteins within cells.

    Mark Goulian;Sanford M. Simon

  • Signal peptides open protein-conducting channels in E. coli.

    Sanford M. Simon;Günter Blobel;Günter Blobel

Frequent Co-Authors

Susan S. Taylor
Susan S. Taylor University of California, San Diego
Paul D. Bieniasz
Paul D. Bieniasz Rockefeller University
Yu Chen
Yu Chen Memorial Sloan Kettering Cancer Center
Martin Kampmann
Martin Kampmann University of California, San Francisco
Yu Chen
Yu Chen New York University
Michael P. LaQuaglia
Michael P. LaQuaglia Memorial Sloan Kettering Cancer Center
Hedi Mattoussi
Hedi Mattoussi Florida State University
Alexandre Benmerah
Alexandre Benmerah Institut Imagine
Gianluigi Veglia
Gianluigi Veglia University of Minnesota
Scott W. Lowe
Scott W. Lowe Memorial Sloan Kettering Cancer Center

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