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Genetics

D-Index
54
Citations
7759
World Ranking
3668
National Ranking
248

Overview

Rüdiger Schmitt is affiliated with the University of Regensburg in Germany and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with a specific focus on molecular biology and medicine. Their research spans several subfields including critical care and intensive care medicine, epidemiology, genetics, and cancer research.

The main topics covered by their work include:

  • Muscle Physiology and Disorders
  • Histone Deacetylase Inhibitors Research
  • Intensive Care Unit Cognitive Disorders
  • Single-cell and spatial transcriptomics
  • Kruppel-like factors research
  • Cancer, Hypoxia, and Metabolism
  • Frailty in Older Adults

Rüdiger Schmitt has published multiple papers in a variety of scientific journals. Notable recent publications include:

  • Single-cell deconstruction of post-sepsis skeletal muscle and adipose tissue microenvironments (2020), Journal of Cachexia Sarcopenia and Muscle
  • Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth (2023), Communications Biology
  • A TGF-β/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer (2023), Proceedings of the National Academy of Sciences
  • Anticachectic regulator analysis reveals Perp-dependent antitumorigenic properties of 3-methyladenine in pancreatic cancer (2021), JCI Insight
  • Muscle stem cells contribute to long-term tissue repletion following surgical sepsis (2023), Journal of Cachexia Sarcopenia and Muscle

The frequent publication venues where Schmitt's research appears include:

  • Cancer Research
  • Journal of Cachexia Sarcopenia and Muscle
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cytotherapy
  • Communications Biology

During the course of their career, Schmitt has collaborated regularly with several co-authors. Frequent collaborators include:

  • Jason D. Doles
  • Aneesha Dasgupta
  • Dong Seong Cho
  • Alexandra M. Ducharme
  • Paige C. Arneson-Wissink

Their research primarily focuses on mechanisms underlying muscle physiology and muscle wasting, with an emphasis on molecular signaling pathways, cancer-related muscle atrophy, and the impact of sepsis on muscle tissue regeneration. The integration of single-cell transcriptomic technologies features prominently in their investigations to dissect complex tissue microenvironments.

Best Publications

  • Genomic Analysis of Organismal Complexity in the Multicellular Green Alga Volvox carteri

    Simon E. Prochnik;James Umen;Aurora M. Nedelcu;Armin Hallmann

  • An engineered Streptomyces hygroscopicus aph 7" gene mediates dominant resistance against hygromycin B in Chlamydomonas reinhardtii.

    Peter Berthold;Rüdiger Schmitt;Wolfgang Mages

  • The tetracycline resistance determinants of RP1 and Tnl721: nucleotide sequence analysis

    Simon H. Waters;Peter Rogowsky;John Grinsted;Josef Altenbuchner

  • Silicibacter pomeroyi sp. nov. and Roseovarius nubinhibens sp. nov., dimethylsulfoniopropionate- demethylating bacteria from marine environments

    José M. González;Joseph S. Covert;William B. Whitman;James R. Henriksen

  • The Tn21 subgroup of bacterial transposable elements.

    John Grinsted;Fernando De La Cruz;Ru¨diger Schmitt

  • Motility and Chemotaxis in Two Strains of Rhizobium with Complex Flagella

    Rudolf Götz;Norbert Limmer;Kurt Ober;Rüdiger Schmitt

  • Bacterial chemotaxis: Rhodobacter sphaeroides and Sinorhizobium meliloti--variations on a theme?

    Judith P. Armitage;Rudiger Schmitt

  • Phosphotransfer between CheA, CheY1, and CheY2 in the Chemotaxis Signal Transduction Chain of Rhizobium meliloti†

    Victor Sourjik;Rüdiger Schmitt

  • Complete nucleotide sequence of Tn1721: gene organization and a novel gene product with features of a chemotaxis protein

    Helmut Allmeier;Bronislava Cresnar;Michaela Greck;Rüdiger Schmitt

  • Tn1721 derivatives for transposon mutagenesis, restriction mapping and nucleotide sequence analysis.

    David Ubben;Rüdiger Schmitt

  • Phylogenetic relationships of the green alga Volvox carteri deduced from small-subunit ribosomal RNA comparisons.

    Helmut Rausch;Niels Larsen;Rüdiger Schmitt

  • Nucleotide sequences and operon structure of plasmid-borne genes mediating uptake and utilization of raffinose in Escherichia coli.

    C Aslanidis;K Schmid;R Schmitt

  • Complete genome sequencing of Agrobacterium sp. H13-3, the former Rhizobium lupini H13-3, reveals a tripartite genome consisting of a circular and a linear chromosome and an accessory plasmid but lacking a tumor-inducing Ti-plasmid

    Daniel Wibberg;Jochen Blom;Sebastian Jaenicke;Florian Kollin

  • VisN and VisR Are Global Regulators of Chemotaxis, Flagellar, and Motility Genes in Sinorhizobium (Rhizobium) meliloti

    Victor Sourjik;Paul Muschler;Birgit Scharf;Rüdiger Schmitt

  • Different roles of CheY1 and CheY2 in the chemotaxis of Rhizobium meliloti.

    Victor Sourjik;Rüdiger Schmitt

  • TnMax — a versatile mini-transposon for the analysis of cloned genes and shuttle mutagenesis

    Rainer Haas;Andreas F. Kahrs;Dirk Facius;Helmut Allmeier

  • Plasmid-mediated sucrose metabolism in Escherichia coli K12: mapping of the scr genes of pUR400.

    K. Schmid;R. Ebner;J. Altenbuchner;R. Schmitt

  • DNA sequences of and complementation by the tnpR genes of Tn21, Tn501 and Tn1721.

    W. P. Diver;J. Grinsted;D. C. Fritzinger;N. L. Brown

  • Three genes of a motility operon and their role in flagellar rotary speed variation in Rhizobium meliloti.

    J Platzer;W Sterr;M Hausmann;R Schmitt

  • Identification and sequence analysis of two related flagellin genes in Rhizobium meliloti.

    E Pleier;R Schmitt

Frequent Co-Authors

Peter M. Rogowsky
Peter M. Rogowsky École Normale Supérieure de Lyon
Victor Sourjik
Victor Sourjik Max Planck Society
Frank Mayer
Frank Mayer University of Göttingen
Hans Robert Kalbitzer
Hans Robert Kalbitzer University of Regensburg
Ivan Raška
Ivan Raška Charles University
Alfred Pühler
Alfred Pühler Bielefeld University
Ernst Freese
Ernst Freese MRC Laboratory of Molecular Biology
Klaus Palme
Klaus Palme University of Freiburg
Karl O. Stetter
Karl O. Stetter University of Regensburg
Reinhard Rachel
Reinhard Rachel University of Regensburg

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