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Genetics

D-Index
71
Citations
20641
World Ranking
2182
National Ranking
272

Research.com Recognitions

  • 2014 - Fellow of the Royal Society, United Kingdom
  • 2005 - Fellow of the Royal Society of Edinburgh

Overview

Peter D. Keightley is affiliated with the University of Edinburgh in the United Kingdom and conducts research primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields, including Genetics, Molecular Biology, Plant Science, Renewable Energy, Sustainability and the Environment, and Ecology.

The scientist's research topics cover a range of genetic and evolutionary studies, with a focus on Evolution and Genetic Dynamics, Genetic diversity and population structure, Chromosomal and Genetic Variations, Genomics and Phylogenetic Studies, Genetic Mapping and Diversity in Plants and Animals, CRISPR and Genetic Engineering, and Algal biology and biofuel production.

Recent publications by Peter D. Keightley include:

  • "Recommendations for improving statistical inference in population genomics," 2022, PLoS Biology
  • "Comparative genomics of Chlamydomonas," 2021, The Plant Cell
  • "Variation in mutation, recombination, and transposition rates in Drosophila melanogaster and Drosophila simulans," 2023, Genome Research
  • "Cis-regulatory evolution spotlights species differences in the adaptive potential of gene expression plasticity," 2021, Nature Communications
  • "Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site," 2020, Heredity

Peter D. Keightley frequently collaborates with other researchers, including:

  • Rory J. Craig
  • Jobran Chebib
  • Eugenio López-Cortegano
  • Rob W. Ness
  • Diethard Tautz

The scientist regularly publishes in several venues, with multiple contributions to bioRxiv (Cold Spring Harbor Laboratory), Genome Research, PLoS Biology, Molecular Biology and Evolution, and The Plant Cell.

Among recognitions received, Peter D. Keightley was made a Fellow of the Royal Society of Edinburgh in 2005 and a Fellow of the Royal Society, United Kingdom, in 2014.

Best Publications

  • Evolution of genes and genomes on the Drosophila phylogeny.

    Andrew G. Clark;Michael B. Eisen;Michael B. Eisen;Douglas R. Smith;Casey M. Bergman

  • The distribution of fitness effects of new mutations

    Adam Eyre-Walker;Adam Eyre-Walker;Peter D. Keightley

  • Understanding quantitative genetic variation.

    Nicholas H. Barton;Peter D. Keightley

  • Spontaneous Mutation Accumulation Studies in Evolutionary Genetics

    Daniel L. Halligan;Peter D. Keightley

  • High genomic deleterious mutation rates in hominids

    Adam Eyre-Walker;Peter D. Keightley

  • Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change

    Adam Eyre-Walker;Peter D. Keightley

  • Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila

    Cathy Haag-Liautard;Mark Dorris;Xulio Maside;Steven Macaskill

  • Interference among deleterious mutations favours sex and recombination in finite populations

    Peter D. Keightley;Sarah P. Otto

  • Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines.

    Peter D. Keightley;Urmi Trivedi;Marian Thomson;Fiona Oliver

  • Enhanced CpG Mutability and Tumorigenesis in MBD4-Deficient Mice

    Catherine B. Millar;Jacky Guy;Owen J. Sansom;Jim Selfridge

  • Joint Inference of the Distribution of Fitness Effects of Deleterious Mutations and Population Demography Based on Nucleotide Polymorphism Frequencies

    Peter D Keightley;Adam Eyre-Walker

  • Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster

    Cathy Haag-Liautard;Nicole Coffey;David Houle;Michael Lynch

  • Estimation of the Spontaneous Mutation Rate in Heliconius melpomene

    Peter D Keightley;Ana Pinharanda;Rob W Ness;Fraser Simpson

  • The distribution of mutation effects on viability in Drosophila melanogaster.

    Peter D. Keightley

  • Estimation of the spontaneous mutation rate per nucleotide site in a Drosophila melanogaster full-sib family

    Peter D Keightley;Rob W Ness;Daniel L Halligan;Penelope R Haddrill

  • Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison

    Daniel L. Halligan;Peter D. Keightley

  • GENOMIC MUTATION RATES FOR LIFETIME REPRODUCTIVE OUTPUT AND LIFESPAN IN CAENORHABDITIS ELEGANS

    Peter D. Keightley;Armando Caballero

  • Deleterious Mutations and the Evolution of Sex

    Peter D. Keightley;Adam Eyre-Walker

  • Evidence for widespread degradation of gene control regions in hominid genomes.

    Peter D Keightley;Martin J Lercher;Adam Eyre-Walker

  • A Comparison of Models to Infer the Distribution of Fitness Effects of New Mutations

    Athanasios Kousathanas;Peter D Keightley

Frequent Co-Authors

Adam Eyre-Walker
Adam Eyre-Walker University of Sussex
Armando Caballero
Armando Caballero Universidade de Vigo
William G. Hill
William G. Hill University of Edinburgh
Daniel J. Gaffney
Daniel J. Gaffney Wellcome Sanger Institute
Brian Charlesworth
Brian Charlesworth University of Edinburgh
Michael Lynch
Michael Lynch Arizona State University
Sarah P. Otto
Sarah P. Otto University of British Columbia
Sergey V. Nuzhdin
Sergey V. Nuzhdin University of Southern California
Peter M. Visscher
Peter M. Visscher University of Oxford
Albert Tenesa
Albert Tenesa University of Edinburgh

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