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Genetics

D-Index
65
Citations
16164
World Ranking
2697
National Ranking
27

Overview

Per Guldberg is affiliated with the University of Southern Denmark in Denmark. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on Molecular Biology, Oncology, Immunology, Surgery, and Cancer Research.

The main topics addressed in their work include:

  • Melanoma and MAPK Pathways
  • Immunotherapy and Immune Responses
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Cutaneous Melanoma Detection and Management
  • Biochemical and Molecular Research
  • RNA Interference and Gene Delivery

Frequent co-authors collaborating with Per Guldberg are:

  • Christina Dahl
  • Morten F. Gjerstorff
  • Henrik J. Ditzel
  • Sofie Traynor
  • Salvatore Rizza

The scientist has published regularly in several venues, particularly:

  • Nature Communications
  • Journal for ImmunoTherapy of Cancer
  • Nature Cell Biology
  • Frontiers in Oncology
  • Cancer Letters

Some recent publications by Per Guldberg include:

  • Loss of Ambra1 promotes melanoma growth and invasion, 2021, Nature Communications
  • NAD+ regulates nucleotide metabolism and genomic DNA replication, 2023, Nature Cell Biology
  • The Cancer/Testis Antigen Gene VCX2 Is Rarely Expressed in Malignancies but Can Be Epigenetically Activated Using DNA Methyltransferase and Histone Deacetylase Inhibitors, 2021, Frontiers in Oncology
  • DNA methyltransferase inhibition promotes recruitment of myeloid-derived suppressor cells to the tumor microenvironment through induction of tumor cell-intrinsic interleukin-1, 2022, Cancer Letters
  • Elevated Expression of SLC6A4 Encoding the Serotonin Transporter (SERT) in Gilles de la Tourette Syndrome, 2021, Genes

Best Publications

  • DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

    Jirina Bartkova;Zuzana Horejsí;Karen Koed;Alwin Krämer

  • Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2′-deoxycytidine (decitabine) treatment

    Michael Daskalakis;Tudung T. Nguyen;Carvell Nguyen;Per Guldberg

  • Disruption of the MMAC1/PTEN Gene by Deletion or Mutation Is a Frequent Event in Malignant Melanoma

    P. Guldberg;P. Thor Straten;A. Birck;V. Ahrenkiel

  • Adult human mesenchymal stem cell as a target for neoplastic transformation.

    Nedime Serakinci;Per Guldberg;Jorge S Burns;Basem Abdallah

  • The p16-cyclin D/Cdk4-pRb Pathway as a Functional Unit Frequently Altered in Melanoma Pathogenesis

    Jirina Bartkova;Jiri Lukas;Per Guldberg;Jan Alsner

  • Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

    Christoph Bock;Florian Halbritter;Francisco J. Carmona;Sascha Tierling

  • In-tube DNA methylation profiling by fluorescence melting curve analysis.

    Jesper Worm;Anni Aggerholm;Per Guldberg

  • Assignment of an autosomal sex reversal locus (SRA1) and campomelic dysplasia (CMPD1) to 17q24.3-q25.1.

    N. Tommerup;W. Schempp;P. Meinecke;S. Pedersen

  • DNA methylation analysis techniques

    Christina Dahl;Per Guldberg

  • Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients.

    Anni Aggerholm;Mette S. Holm;Per Guldberg;Lene H. Olesen

  • Molecular Analysis of Phenylketonuria in Denmark: 99% of the Mutations Detected by Denaturing Gradient Gel Electrophoresis

    Per Guldberg;Karen Friis Henriksen;Flemming Güttler

  • Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells.

    Jorge S. Burns;Basem M. Abdallah;Per Guldberg;Jørgen Rygaard

  • Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene

    Arnaldur Hall;Kathrine Damm Meyle;Marina Krarup Lange;Martin Klima

  • The genome and epigenome of malignant melanoma.

    Christina Dahl;Per Guldberg

  • Spontaneous human squamous cell carcinomas are killed by a human cytotoxic T lymphocyte clone recognizing a wild-type p53-derived peptide.

    Mads Röpke;Jesper Hald;Per Guldberg;Jesper Zeuthen

  • Mutation and Allelic Loss of the PTEN/MMAC1 gene in Primary and Metastatic Melanoma Biopsies

    Anette Birck;Vibeke Ahrenkiel;Jesper Zeuthen;Klaus Hou-Jensen

  • Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.

    Jesper Worm;Alexei F. Kirkin;Karine N. Dzhandzhugazyan;Per Guldberg

  • Extensive intra- and interindividual heterogeneity of p15INK4B methylation in acute myeloid leukemia.

    Anni Aggerholm;Per Guldberg;Marianne Hokland;Peter Hokland

  • Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma.

    Per Guldberg;Per thor Straten;Vibeke Ahrenkiel;Tina Seremet

  • Mutational spectrum of phenylalanine hydroxylase deficiency in Sicily: Implications for diagnosis of hyperphenylalaninemia in Southern Europe

    Per Guldberg;Valentino Romano;Nadia Ceratto;Paolo Bosco

Frequent Co-Authors

Peter Hokland
Peter Hokland Aarhus University
Per thor Straten
Per thor Straten University of Copenhagen
Jürgen C. Becker
Jürgen C. Becker University of Duisburg-Essen
John D. Boice
John D. Boice Vanderbilt University
Eugene Lukanidin
Eugene Lukanidin University of Copenhagen
Jiri Bartek
Jiri Bartek Karolinska Institute
Jirina Bartkova
Jirina Bartkova Karolinska Institute
Jiri Lukas
Jiri Lukas University of Copenhagen
Marilyn Stovall
Marilyn Stovall The University of Texas MD Anderson Cancer Center
Zeynep Tümer
Zeynep Tümer Copenhagen University Hospital

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