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Chemistry

D-Index
47
Citations
6407
World Ranking
15809
National Ranking
350

Overview

Paul R. Gooley is affiliated with the University of Melbourne in Australia and has a research portfolio spanning medicine and biochemistry, genetics, and molecular biology. Their work prominently intersects molecular biology and cellular and molecular neuroscience, with additional engagement in virology, immunology, and psychiatry and mental health.

The scientist's research focuses on several main topics, including:

  • Receptor Mechanisms and Signaling
  • Neuropeptides and Animal Physiology
  • Rabies Epidemiology and Control
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Genetic Neurodegenerative Diseases
  • Monoclonal and Polyclonal Antibodies Research
  • Virology and Viral Diseases

Paul R. Gooley has published multiple papers, with notable recent work including:

  • "Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38," 2020, Nature Communications
  • "The underlying sex differences in neuroendocrine adaptations relevant to Myalgic Encephalomyelitis Chronic Fatigue Syndrome," 2022, Frontiers in Neuroendocrinology
  • "The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement," 2020, Journal of Biological Chemistry
  • "N- and C-terminal regions of αB-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation," 2020, Journal of Biological Chemistry
  • "Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL," 2022, Cell Death and Differentiation

Frequent coauthors in their publications are:

  • Ashish Sethi
  • Daniel J. Scott
  • Fei Yan
  • Michael D. W. Griffin
  • Ross A. D. Bathgate

Their work has been published repeatedly in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Nature Communications
  • Journal of Molecular Biology
  • Journal of Virology

Best Publications

  • Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

    John W. Scott;Bryce J.W. van Denderen;Sebastian B. Jorgensen;Jane E. Honeyman

  • Macromolecular NMR spectroscopy for the non-spectroscopist

    Ann H. Kwan;Mehdi Mobli;Paul R. Gooley;Glenn F. King

  • Optimisation of NMR dynamic models I. Minimisation algorithms and their performance within the model-free and Brownian rotational diffusion spaces.

    Edward J. d’Auvergne;Paul R. Gooley

  • Role of monoterpenes in grape and wine flavor.

    Christopher R. Strauss;Bevan Wilson;Paul R. Gooley;Patrick J. Williams

  • Optimisation of NMR dynamic models II. A new methodology for the dual optimisation of the model-free parameters and the Brownian rotational diffusion tensor

    Edward J. d’Auvergne;Paul R. Gooley

  • The NMR structure of the inhibited catalytic domain of human stromelysin-1.

    Paul R. Gooley;John F. O'Connell;Alice I. Marcy;Gregory C. Cuca

  • SnRK1 from Arabidopsis thaliana is an atypical AMPK.

    Shane Emanuelle;Mohammed Iqbal Hossain;Isabel E. Moller;Henriette L. Pedersen

  • The use of model selection in the model-free analysis of protein dynamics

    Edward J. d'Auvergne;Paul R. Gooley

  • Molecular Insights into the Enigmatic Metabolic Regulator, SnRK1

    Shane Emanuelle;Monika S. Doblin;David I. Stapleton;Antony Bacic

  • Convergent Evolution of Receptors for Protein Import into Mitochondria

    Andrew J Perry;Joanne M Hulett;Vladimir A Likic;Trevor James Lithgow

  • Membrane receptors: Structure and function of the relaxin family peptide receptors

    Roy C.K. Kong;Patrick J. Shilling;Derek K. Lobb;Paul R. Gooley

  • Application of droplet countercurrent chromatography to the analysis of conjugated forms of terpenoids, phenols, and other constituents of grape juice

    Christopher R. Strauss;Paul R. Gooley;Bevan Wilson;Patrick J. Williams

  • A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a.

    Natalie J. Saez;Mehdi Mobli;Michael Bieri;Irène R. Chassagnon

  • Regulation of Starch Stores by a Ca2+-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii

    Alessandro D. Uboldi;Alessandro D. Uboldi;James M. McCoy;James M. McCoy;Martin Blume;Motti Gerlic;Motti Gerlic

  • NMR structure of human apolipoprotein C-II in the presence of sodium dodecyl sulfate.

    Christopher A. MacRaild;Danny M. Hatters;Geoffrey J. Howlett;Paul R. Gooley

  • relaxGUI: a new software for fast and simple NMR relaxation data analysis and calculation of ps-ns and μs motion of proteins

    Michael Bieri;Edward J. d’Auvergne;Paul R. Gooley

  • Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1.

    Wai Yee Low;Susanne C Feil;Susanne C Feil;Hooi Ling Ng;Michael Anthony Gorman

  • Automated NMR relaxation dispersion data analysis using NESSY

    Michael Bieri;Paul R Gooley

  • Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination.

    Michael Bieri;Ann H. Kwan;Mehdi Mobli;Glenn F. King

  • AMPK β subunits display isoform specific affinities for carbohydrates

    Ann Koay;Ben Woodcroft;Emma J. Petrie;Helen Yue

  • Structure, topology and function of the translocase of the outer membrane of mitochondria.

    Andrew J Perry;Kieran A Rimmer;Haydyn D T Mertens;Ross Waller

  • NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome

    Christopher W. Armstrong;Neil R. McGregor;John R. Sheedy;Ian Buttfield

  • Article Convergent Evolution of Receptors for Protein Import into Mitochondria

    Andrew J. Perry;Joanne M. Hulett;Vladimir A. Likic;Trevor Lithgow

Frequent Co-Authors

Ross A. D. Bathgate
Ross A. D. Bathgate Florey Institute of Neuroscience and Mental Health
Daniel Scott
Daniel Scott University of Waterloo
Geoffrey J. Howlett
Geoffrey J. Howlett University of Melbourne
Malcolm J. McConville
Malcolm J. McConville University of Melbourne
David Stapleton
David Stapleton Florey Institute of Neuroscience and Mental Health
Trevor Lithgow
Trevor Lithgow Monash University
Raymond S. Norton
Raymond S. Norton Monash University
Irene Yarovsky
Irene Yarovsky RMIT University
John D. Wade
John D. Wade Florey Institute of Neuroscience and Mental Health
Michael W. Parker
Michael W. Parker University of Melbourne

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