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Neuroscience

D-Index
40
Citations
6247
World Ranking
8099
National Ranking
374

Overview

Pascal Legendre is affiliated with Université Paris Cité in France and has a research profile centered primarily on neuroscience and biochemistry. Their work spans several interconnected fields that include neuroscience, biochemistry, genetics, and molecular biology, with a focus on cellular and molecular neuroscience. Additional subfields involve cell biology, biophysics, cognitive neuroscience, and developmental neuroscience.

Legendre's research touches on a variety of main topics such as neuroscience and neuropharmacology, photoreceptor and optogenetics research, zebrafish biomedical research applications, advanced fluorescence microscopy techniques, neural dynamics and brain function, neurogenesis and neuroplasticity mechanisms, as well as studies on nicotinic acetylcholine receptors.

The scientist's recent publications illustrate this diverse research focus. These papers include:

  • Electrophysiology of ionotropic GABA receptors, 2021, Cellular and Molecular Life Sciences
  • Dynamic regulation of the cholinergic system in the spinal central nervous system, 2020, Scientific Reports
  • Differential regulation of glycinergic and GABAergic nanocolumns at mixed inhibitory synapses, 2021, EMBO Reports
  • Mapping astrocyte activity domains by light sheet imaging and spatio-temporal correlation screening, 2020, NeuroImage
  • Trans-inhibition of axon terminals underlies competition in the habenulo-interpeduncular pathway, 2021, Current Biology

Legendre frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, Current Biology, Zenodo (CERN European Organization for Nuclear Research), and Cellular and Molecular Life Sciences. The accumulation of papers in these venues reflects an ongoing engagement with prominent platforms in life sciences and neuroscience research.

Collaboration is a notable aspect of Legendre's research activity. Frequent co-authors include Hervé Le Corronc, Jean-Marie Mangin, Erika Bullier, Elim Hong, and Antoine Triller. These collaborations highlight a network of researchers contributing extensively to overlapping scientific domains.

Best Publications

  • The glycinergic inhibitory synapse.

    Legendre P

  • Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium

    P Legendre;C Rosenmund;GL Westbrook

  • Characterization of rat spinal cord receptors to FLFQPQRFamide, a mammalian morphine modulating peptide: a binding study.

    M. Allard;S. Geoffre;P. Legendre;J.D. Vincent

  • Complex invasion pattern of the cerebral cortex bymicroglial cells during development of the mouse embryo.

    Nina Swinnen;Sophie Smolders;Ariel Avila;Kristof Notelaers;Kristof Notelaers

  • The inhibition of single N-methyl-D-aspartate-activated channels by zinc ions on cultured rat neurones.

    P. Legendre;Gary Westbrook

  • Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.

    Unknown

  • Refuting the challenges of the developmental shift of polarity of GABA actions: GABA more exciting than ever!

    Yehezkel Ben-Ari;Melanie A. Woodin;Evelyne Sernagor;Laura Cancedda

  • Expression of NMDA channels on cerebellar Purkinje cells acutely dissociated from newborn rats.

    C. Rosenmund;P. Legendre;G. L. Westbrook

  • Dopamine inhibits two characterized voltage-dependent calcium currents in identified rat lactotroph cells.

    Pierre-Marie Lledo;Pascal Legendre;Jean-Marc Israel;Jean-Didier Vincent

  • Automatic detection of spontaneous synaptic responses in central neurons.

    N. Ankri;P. Legendre;D.S. Faber;H. Korn

  • Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy.

    Sabrina A. Eichler;Sergei Kirischuk;René Jüttner;Philipp K. Schafermeier

  • Microglia: Brain cells on the move.

    Sophie Marie-Thérèse Smolders;Sofie Kessels;Tim Vangansewinkel;Jean-Michel Rigo

  • Pattern of invasion of the embryonic mouse spinal cord by microglial cells at the time of the onset of functional neuronal networks

    C. Rigato;R. Buckinx;H. Le-Corronc;H. Le-Corronc;H. Le-Corronc;Jean-Michel Rigo

  • A Reluctant Gating Mode of Glycine Receptor Channels Determines the Time Course of Inhibitory Miniature Synaptic Events in Zebrafish Hindbrain Neurons

    Pascal Legendre

  • Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism

    M. Pilorge;M. Pilorge;M. Pilorge;C. Fassier;C. Fassier;C. Fassier;H. Le Corronc;A. Potey;A. Potey;A. Potey

  • Electrophysiology of ionotropic GABA receptors

    Erwan Sallard;Diane Letourneur;Pascal Legendre

  • Transforming growth factor alpha promotes sequential conversion of mature astrocytes into neural progenitors and stem cells.

    A. Sharif;A. Sharif;P. Legendre;V. Prevot;C. Allet

  • Kinetic properties of the α2 homo‐oligomeric glycine receptor impairs a proper synaptic functioning

    J. M. Mangin;M. Baloul;L. Prado de Carvalho;B. Rogister

  • GLYCINERGIC INHIBITORY SYNAPTIC CURRENTS AND RELATED RECEPTOR CHANNELS IN THE ZEBRAFISH BRAIN

    P. Legendre;H. Korn

  • Asymmetric Cross-inhibition between GABAA and Glycine Receptors in Rat Spinal Dorsal Horn Neurons *

    Yong Li;Long Jun Wu;Pascal Legendre;Tian Le Xu

  • Splice-specific roles of glycine receptor alpha3 in the hippocampus.

    Sabrina A. Eichler;Benjamin Förstera;Birthe Smolinsky;René Jüttner

  • Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo.

    Silke Smolders;Sophie M. T. Smolders;Nina Swinnen;Annette Gärtner

  • Effects of dopamine on voltage-dependent potassium currents in identified rat lactotroph cells

    Pierre-Marie Lledo;Pascal Legendre;Jin Zhang;Jean-Marc Israel

Frequent Co-Authors

Jean-Didier Vincent
Jean-Didier Vincent Centre national de la recherche scientifique, CNRS
Antoine Triller
Antoine Triller École Normale Supérieure
Guy Simonnet
Guy Simonnet University of Bordeaux
Catalina Betancur
Catalina Betancur Sorbonne University
Pierre Meyrand
Pierre Meyrand University of Bordeaux
Richard P. Michael
Richard P. Michael Emory University
Pierre Drapeau
Pierre Drapeau University of Montreal
Michèle Allard
Michèle Allard Centre national de la recherche scientifique, CNRS
Bernard Rogister
Bernard Rogister University of Liège
Dongdong Li
Dongdong Li Huazhong University of Science and Technology

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