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Genetics

D-Index
97
Citations
64235
World Ranking
826
National Ranking
115

Medicine

D-Index
98
Citations
65077
World Ranking
8728
National Ranking
850

Overview

Nigel Williams is a researcher affiliated with Cardiff University in the United Kingdom, with a focus on medicine, biochemistry, genetics, and molecular biology. Their research spans multiple subfields including neurology, genetics, molecular biology, physiology, and cellular and molecular neuroscience.

The main topics of Nigel Williams's work include:

  • Parkinson's Disease Mechanisms and Treatments
  • Genetics and Neurodevelopmental Disorders
  • Genomic variations and chromosomal abnormalities
  • Lysosomal Storage Disorders Research
  • Neurological diseases and metabolism
  • Genetic Neurodegenerative Diseases
  • Genetic Associations and Epidemiology

Williams has contributed to a range of publications, with frequent appearances in these venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Parkinson s Disease
  • Nature Communications
  • Journal of Neurology Neurosurgery & Psychiatry
  • Translational Psychiatry

Notable recent papers include:

  • "Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome," 2021, Nature Communications
  • "Genome-Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease," 2020, Movement Disorders
  • "Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 deletion syndrome," 2020, Nature Medicine
  • "Timing and Impact of Psychiatric, Cognitive, and Motor Abnormalities in Huntington Disease," 2021, Neurology
  • "Identification of sixteen novel candidate genes for late onset Parkinson's disease," 2021, Molecular Neurodegeneration

Frequent co-authors collaborating with Williams include:

  • Huw R. Morris
  • Manuela Tan
  • Donald G. Grosset
  • Joshua Shulman
  • Michael Lawton

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

    Alan E. Renton;Elisa Majounie;Adrian James Waite;Javier Simón-Sánchez;Javier Simón-Sánchez

  • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

    Shaun M. Purcell;Shaun M. Purcell;Naomi R. Wray;Jennifer L. Stone;Jennifer L. Stone;Peter M. Visscher

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    Ditte Demontis;Ditte Demontis;Raymond K Walters;Raymond K Walters;Joanna Martin;Joanna Martin;Joanna Martin;Manuel Mattheisen

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

    Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia

    Cathryn M. Lewis;Douglas F. Levinson;Lesley H. Wise;Lynn E. DeLisi

  • Rare chromosomal deletions and duplications increase risk of schizophrenia

    Jennifer L. Stone;Jennifer L. Stone;Jennifer L. Stone;Michael C. O’Donovan;Hugh Gurling;George K. Kirov

  • Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

    Elisa Majounie;Alan E. Renton;Kin Mok;Elise G. P. Dopper;Elise G. P. Dopper

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Identification of loci associated with schizophrenia by genome-wide association and follow-up

    Michael C. O'Donovan;Nicholas Craddock;Nadine Norton;Hywel Williams

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Alexander Gusev;S. Hong Lee;Gosia Trynka;Hilary Finucane

  • Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis

    Nigel Melville Williams;Irina Zaharieva;Andrew Kenneth Martin;Kate Langley

  • Meta-Analysis of Genome-Wide Association Studies of Attention- Deficit/Hyperactivity Disorder

    Benjamin M. Neale;Benjamin M. Neale;Sarah E. Medland;Sarah E. Medland;Stephan Ripke;Stephan Ripke;Philip Asherson

Frequent Co-Authors

Michael John Owen
Michael John Owen Cardiff University
Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Peter Holmans
Peter Holmans Cardiff University
Nadine Norton
Nadine Norton Mayo Clinic
George Kirov
George Kirov Cardiff University
Hywel Williams
Hywel Williams University College London
Nicholas John Craddock
Nicholas John Craddock Cardiff University
Nicholas W. Wood
Nicholas W. Wood University College London
Marian L. Hamshere
Marian L. Hamshere Cardiff University
John Hardy
John Hardy University College London

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