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Genetics
USA
2024

D-Index & Metrics

Genetics

D-Index
134
Citations
93362
World Ranking
223
National Ranking
116

Medicine

D-Index
138
Citations
99996
World Ranking
1797
National Ranking
1028

Research.com Recognitions

  • 2024 - Research.com Genetics in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Neil Risch is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broad areas, they have contributed substantially to Genetics, Cardiology and Cardiovascular Medicine, Surgery, Molecular Biology, and Pediatrics, Perinatology and Child Health.

The scientist's work focuses on several main topics that include Genetic Associations and Epidemiology, Genomics and Rare Diseases, Lipoproteins and Cardiovascular Health, Prenatal Screening and Diagnostics, BRCA gene mutations in cancer, Genomic variations and chromosomal abnormalities, and Genetics and Neurodevelopmental Disorders.

Neil Risch has authored multiple papers, some of which include:

  • A brief history of human disease genetics, 2020, Nature
  • The role of exome sequencing in newborn screening for inborn errors of metabolism, 2020, Nature Medicine
  • Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia, 2022, Nature Genetics
  • European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation, 2023, Nature Communications
  • Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk, 2020, Nature Communications

Frequent co-authors in their research include:

  • Thomas J. Hoffmann
  • Catherine Schaefer
  • Pui-Yan Kwok
  • Akinyemi Oni-Orisan
  • Mark Kvale

Their work has been published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, npj Genomic Medicine, Alzheimer's & Dementia, and The American Journal of Human Genetics.

In recognition of contributions to science, Neil Risch was awarded the distinction of Fellow by the American Association for the Advancement of Science (AAAS) in 2009.

Best Publications

  • The Future of Genetic Studies of Complex Human Diseases

    Neil Risch;Kathleen Merikangas

  • Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis

    Lindsay A. Farrer;L. Adrienne Cupples;Jonathan L. Haines;Bradley T Hyman

  • A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

    J.N. Feder;A. Gnirke;W. Thomas;Z. Tsuchihashi

  • Searching for genetic determinants in the new millennium

    Neil J. Risch

  • Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

    Joachim Hallmayer;Sue Cleveland;Andrea Torres;Jennifer Phillips

  • Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.

    Corder Eh;Saunders Am;Risch Nj;Strittmatter Wj

  • Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease.

    David Botstein;Neil Risch;Neil Risch

  • Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression: A Meta-analysis

    Neil Risch;Richard Herrell;Thomas Lehner;Kung Yee Liang

  • Linkage strategies for genetically complex traits. I. Multilocus models.

    N Risch

  • Genetic Susceptibility to Death from Coronary Heart Disease in a Study of Twins

    M E Marenberg;N Risch;L F Berkman;B Floderus

  • Candidate-gene approaches for studying complex genetic traits: practical considerations.

    Holly K. Tabor;Neil J. Risch;Richard M. Myers

  • Autosomal Dominant Inheritance of Early-Onset Breast Cancer: Implications for Risk Prediction

    Elizabeth B. Claus;Neil Risch;W. Douglas Thompson

  • The importance of race and ethnic background in biomedical research and clinical practice.

    Esteban González Burchard;Elad Ziv;Natasha Coyle;Scarlett Lin Gomez

  • A Comparison of Linkage Disequilibrium Measures for Fine-Scale Mapping

    B. Devlin;Neil Risch

  • Genetic analysis of breast cancer in the cancer and steroid hormone study.

    E B Claus;N Risch;W D Thompson

  • Linkage strategies for genetically complex traits. II. The power of affected relative pairs.

    N Risch

  • The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein

    Laurie J. Ozelius;Jeffrey W. Hewett;Curtis E. Page;Susan B. Bressman

  • Categorization of humans in biomedical research: genes, race and disease

    Neil Risch;Neil Risch;Esteban Burchard;Elad Ziv;Hua Tang

  • The genetic attributable risk of breast and ovarian cancer

    Elizabeth B. Claus;Joellen M. Schildkraut;W. Douglas Thompson;Neil J. Risch

  • Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression

    Neil Risch;Richard Herrell;Thomas Lehner;Kung-Yee Liang

Frequent Co-Authors

Hua Tang
Hua Tang Stanford University
Eric Jorgenson
Eric Jorgenson Kaiser Permanente
Pui-Yan Kwok
Pui-Yan Kwok University of California, San Francisco
Laurie J. Ozelius
Laurie J. Ozelius Harvard University
George C. Ebers
George C. Ebers University of Oxford
Carlos Iribarren
Carlos Iribarren Kaiser Permanente
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Patricia L. Kramer
Patricia L. Kramer Oregon Health & Science University
Xandra O. Breakefield
Xandra O. Breakefield Harvard University
Richard M. Myers
Richard M. Myers HudsonAlpha Institute for Biotechnology

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