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Biology and Biochemistry

D-Index
57
Citations
12813
World Ranking
13747
National Ranking
5822

Overview

Nathan R. Treff is affiliated with Rutgers, The State University of New Jersey in the United States. Their research contributions span multiple fields of study, mainly focusing on Medicine and Biochemistry, Genetics, and Molecular Biology.

Their main research subfields include Pediatrics, Perinatology and Child Health, Genetics, Molecular Biology, Public Health, Environmental and Occupational Health, and Plant Science. Treff's work addresses key topics such as Prenatal Screening and Diagnostics, CRISPR and Genetic Engineering, Genomic Variations and Chromosomal Abnormalities, Reproductive Biology and Fertility, Assisted Reproductive Technology and Twin Pregnancy, Genetic Syndromes and Imprinting, and Chromosomal and Genetic Variations.

Some notable recent papers by Treff include:

  • "Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos," 2020, published in Cell
  • "The 'mosaic' embryo: misconceptions and misinterpretations in preimplantation genetic testing for aneuploidy," 2021, published in Fertility and Sterility
  • "Preimplantation genetic testing for aneuploidy: A review of published blastocyst reanalysis concordance data," 2020, published in Prenatal Diagnosis
  • "On the reproductive capabilities of aneuploid human preimplantation embryos," 2022, published in The American Journal of Human Genetics
  • "Preimplantation Genetic Testing for Polygenic Disease Relative Risk Reduction: Evaluation of Genomic Index Performance in 11,883 Adult Sibling Pairs," 2020, published in Genes

Frequent co-authors in Treff's publications include:

  • Diego Marín
  • Jia Xu
  • Bhavini Rana

Treff has contributed extensively to several scientific journals. The primary publication venues include:

  • Fertility and Sterility
  • bioRxiv (Cold Spring Harbor Laboratory)
  • F&S Science
  • The American Journal of Human Genetics
  • Genes

Best Publications

  • The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening

    Jason M. Franasiak;Eric J. Forman;Kathleen H. Hong;Marie D. Werner

  • Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial.

    Richard T. Scott;Kathleen M. Upham;Eric J. Forman;Kathleen H. Hong

  • Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial.

    Richard T. Scott;Kathleen M. Upham;Eric J. Forman;Tian Zhao

  • In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial

    Eric J. Forman;Kathleen H. Hong;Kathleen M. Ferry;Xin Tao

  • Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study

    Richard T. Scott;Kathleen Ferry;Jing Su;Xin Tao

  • Accurate single cell 24 chromosome aneuploidy screening using whole genome amplification and single nucleotide polymorphism microarrays.

    Nathan R. Treff;Jing Su;Xin Tao;Brynn Levy

  • Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants

    Daniel Paull;Valentina Emmanuele;Keren A. Weiss;Nathan Treff

  • SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts

    L. E. Northrop;N. R. Treff;B. Levy;R. T. Scott

  • Endometrial microbiome at the time of embryo transfer: next-generation sequencing of the 16S ribosomal subunit

    J. M. Franasiak;M. D. Werner;C. R. Juneau;X. Tao

  • Development and validation of an accurate quantitative real-time polymerase chain reaction–based assay for human blastocyst comprehensive chromosomal aneuploidy screening

    Nathan R. Treff;Xin Tao;Kathleen M. Ferry;Jing Su

  • Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates

    E.J. Forman;X. Tao;K.M. Ferry;D. Taylor

  • Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos.

    Michael V. Zuccaro;Jia Xu;Carl Mitchell;Diego Marin

  • Human Somatic Cell Nuclear Transfer Using Adult Cells

    Young Gie Chung;Jin Hee Eum;Jeoung Eun Lee;Sung Han Shim

  • Evaluation of targeted next-generation sequencing–based preimplantation genetic diagnosis of monogenic disease

    Nathan R. Treff;Anastasia Fedick;Xin Tao;Batsal Devkota

  • Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patients.

    William B. Schoolcraft;Nathan R. Treff;John M. Stevens;Kathleen Ferry

  • Diagnosis of human preimplantation embryo viability

    David K Gardner;Marcos Meseguer;Carmen Rubio;Nathan R Treff

  • SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISH

    Nathan R. Treff;Brynn Levy;Jing Su;Lesley E. Northrop

  • Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trial using DNA fingerprinting.

    Eric J. Forman;Xinying Li;Kathleen M. Ferry;Katherine Scott

  • Single nucleotide polymorphism microarray-based concurrent screening of 24-chromosome aneuploidy and unbalanced translocations in preimplantation human embryos.

    Nathan R. Treff;Lesley E. Northrop;Khushabu Kasabwala;Jing Su

  • Comparison of array comparative genomic hybridization and quantitative real-time PCR-based aneuploidy screening of blastocyst biopsies.

    Antonio Capalbo;Nathan R Treff;Danilo Cimadomo;Xin Tao

Frequent Co-Authors

Brynn Levy
Brynn Levy Columbia University
Dieter Egli
Dieter Egli Columbia University
Raymond Reeves
Raymond Reeves Washington State University
Jinchuan Xing
Jinchuan Xing Rutgers, The State University of New Jersey
Robert Lanza
Robert Lanza Astellas Pharma (Japan)
Teresa K. Woodruff
Teresa K. Woodruff Northwestern University
Orly Elpeleg
Orly Elpeleg Hebrew University of Jerusalem
Avraham Shaag
Avraham Shaag Hebrew University of Jerusalem
Maria Jasin
Maria Jasin Memorial Sloan Kettering Cancer Center
Michio Hirano
Michio Hirano Columbia University

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