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Neuroscience

D-Index
78
Citations
21834
World Ranking
1767
National Ranking
853

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

M. Maral Mouradian is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily focuses on Medicine and Neuroscience, with a significant number of publications spanning these fields.

Their subfields of expertise include:

  • Neurology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Physiology
  • Cognitive Neuroscience

Main topics covered in their research are:

  • Parkinson's Disease Mechanisms and Treatments
  • Nuclear Receptors and Signaling
  • Neurological disorders and treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Autism Spectrum Disorder Research
  • Alzheimer's disease research and treatments
  • Neurological Disease Mechanisms and Treatments

Mouradian has contributed to a range of scientific journals, frequently publishing in:

  • Annals of Neurology
  • Neurotherapeutics
  • Proceedings of the National Academy of Sciences
  • Pharmacological Reviews
  • Parkinsonism & Related Disorders

They have collaborated extensively with multiple co-authors, including:

  • Gian Pal
  • Sepehr Sani
  • Run Yan
  • Jie Zhang
  • Eunsung Junn

Selected recent papers include:

  • "Metabolome Changes in Cerebral Ischemia," 2020, published in Cells
  • "Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA," 2020, published in Proceedings of the National Academy of Sciences
  • "Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers," 2022, published in Annals of Neurology
  • "Therapeutics in the Pipeline Targeting α-Synuclein for Parkinson's Disease," 2022, published in Pharmacological Reviews
  • "Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera," 2024, published in Proceedings of the National Academy of Sciences

Their research output demonstrates a focus on neurodegenerative diseases, particularly Parkinson's disease, and the molecular biology underlying these conditions.

Mouradian has been recognized as a member of the Association of American Physicians.

Best Publications

  • The Role of Oxidative Stress in Parkinson’s Disease

    Vera Dias;Eunsung Junn;M. Maral Mouradian

  • Sp1 and TAFII130 Transcriptional Activity Disrupted in Early Huntington's Disease

    Anthone W. Dunah;Hyunkyung Jeong;April Griffin;Yong Man Kim

  • Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease.

    M. P. Heyes;K. Saito;J. S. Crowley;L. E. Davis

  • Repression of α-synuclein expression and toxicity by microRNA-7

    Eunsung Junn;Kang-Woo Lee;Byeong Seon Jeong;Teresa W. Chan

  • Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status.

    Melvyn P. Heyes;Bruce J. Brew;Alex Martin;Richard W. Price

  • Amantadine as treatment for dyskinesias and motor fluctuations in Parkinson's disease

    L. Verhagen Metman;P. Del Dotto;P. van den Munckhof;J. Fang

  • Degradation of α-Synuclein by Proteasome *

    M. Catherine Bennett;John F. Bishop;Yan Leng;P. Boon Chock

  • Aggresomes Formed by α-Synuclein and Synphilin-1 Are Cytoprotective

    Mikiei Tanaka;Yong Man Kim;Gwang Lee;Eunsung Junn;Eunsung Junn

  • Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death

    Eunsung Junn;Hiroyuki Taniguchi;Byeong Seon Jeong;Xin Zhao

  • Mitochondrial localization of DJ-1 leads to enhanced neuroprotection.

    Eunsung Junn;Won Hee Jang;Won Hee Jang;Xin Zhao;Byeong Seon Jeong

  • Adenosine A2A receptor antagonist treatment of Parkinson’s disease

    W. Bara-Jimenez;A. Sherzai;T. Dimitrova;A. Favit

  • Recent advances in the genetics and pathogenesis of Parkinson disease

    M. Maral Mouradian

  • Motor fluctuations in Parkinson's disease: Central pathophysiological mechanisms, part II

    M M Mouradian;J L Juncos;G Fabbrini;J Schlegel

  • Human α-Synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine

    Eunsung Junn;M.Maral Mouradian

  • MicroRNAs in neurodegenerative diseases and their therapeutic potential

    Eunsung Junn;M. Maral Mouradian

  • Modification of central dopaminergic mechanisms by continuous levodopa therapy for advanced Parkinson's disease.

    M. Maral Mouradian;Isabella J. E. Heuser;Fabio Baronti;Thomas N. Chase

  • Apoptotic signaling in dopamine-induced cell death: the role of oxidative stress, p38 mitogen-activated protein kinase, cytochrome c and caspases

    Eunsung Junn;M. Maral Mouradian

  • PQBP-1, a Novel Polyglutamine Tract-Binding Protein, Inhibits Transcription Activation By Brn-2 and Affects Cell Survival

    Masaaki Waragai;Claas Hinrich Lammers;Sousuke Takeuchi;Ichiro Imafuku

  • Levodopa pharmacokinetic mechanisms and motor fluctuations in Parkinson's disease

    G. Fabbrini;J. Juncos;M Maral Mouradian;C. Serrati

  • Effects of serotonin 5-HT1A agonist in advanced Parkinson's disease.

    William Bara-Jimenez;Francesco Bibbiani;Michael J. Morris;Tzvetelina Dimitrova

  • Targeting of marrow-derived astrocytes to the ischemic brain

    Martin A. Eglitis;Debbie Dawson;Kun Woo Park;M. Maral Mouradian

  • Enhanced vulnerability to oxidative stress by α-synuclein mutations and C-terminal truncation

    S Kanda;J.F Bishop;M.A Eglitis;Y Yang

  • Wearing-off fluctuations in Parkinson's disease: contribution of postsynaptic mechanisms.

    D. Bravi;M Maral Mouradian;J. W. Roberts;T. L. Davis

  • DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway

    Joo Young Im;Kang Woo Lee;Jong Min Woo;Eunsung Junn

  • Pathogenesis of dyskinesias in parkinson's disease

    M Maral Mouradian;I. J.E. Heuser;F. Baronti;G. Fabbrini

Frequent Co-Authors

Giovanni Fabbrini
Giovanni Fabbrini Sapienza University of Rome
Allen R. Braun
Allen R. Braun Uniformed Services University of the Health Sciences
Hideki Mochizuki
Hideki Mochizuki Osaka University
Patricia K. Sonsalla
Patricia K. Sonsalla Rutgers, The State University of New Jersey
Irene Litvan
Irene Litvan University of California, San Diego
Amelia J. Eisch
Amelia J. Eisch University of Pennsylvania
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Young H. Sohn
Young H. Sohn Yonsei University
Alex Martin
Alex Martin National Institutes of Health
Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai

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