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Chemistry

D-Index
69
Citations
16242
World Ranking
6218
National Ranking
360

Research.com Recognitions

  • 2003 - Corday–Morgan Prize, Royal Society of Chemistry (UK)
  • 1997 - Meldola Medal and Prize, Royal Society of Chemistry (UK)

Overview

Jonathan Clayden is affiliated with the University of Bristol in the United Kingdom. Their research focuses primarily on the fields of Materials Science and Chemistry, with significant contributions in subfields such as Materials Chemistry, Organic Chemistry, Molecular Biology, Spectroscopy, and Pharmaceutical Science.

Their work covers a range of main topics including:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Chemical Synthesis and Analysis
  • Catalytic C-H Functionalization Methods
  • Asymmetric Synthesis and Catalysis
  • Coordination Chemistry and Organometallics
  • Click Chemistry and Applications

Clayden has published extensively, with frequent appearances in publication venues such as The Cambridge Structural Database, Angewandte Chemie International Edition, Angewandte Chemie, Chemical Science, and Nature Communications.

Some of the recent papers authored or coauthored by Clayden include:

  • Switchable foldamer ion channels with antibacterial activity, 2020, Chemical Science
  • Biocatalytic Enantioselective Synthesis of Atropisomers, 2022, Accounts of Chemical Research
  • Photocatalytic Difunctionalization of Vinyl Ureas by Radical Addition Polar Truce-Smiles Rearrangement Cascades, 2020, Angewandte Chemie International Edition
  • De novo design of discrete, stable 310-helix peptide assemblies, 2022, Nature
  • C(sp3)-Arylation by Conformationally Accelerated Intramolecular Nucleophilic Aromatic Substitution (SNAr), 2022, Accounts of Chemical Research

Frequent coauthors collaborating with Clayden include:

  • Matej Žabka
  • Natalie E. Pridmore
  • David Tilly
  • John W. Ward
  • Íñigo J. Vitórica-Yrezábal

Jonathan Clayden has been recognized with awards such as the Corday-Morgan Prize from the Royal Society of Chemistry (UK) in 2003 and the Meldola Medal and Prize from the Royal Society of Chemistry (UK) in 1997.

Best Publications

  • Organolithiums: Selectivity for Synthesis

    Jonathan Clayden

  • The Challenge of Atropisomerism in Drug Discovery

    Jonathan Clayden;Wesley J. Moran;Paul J. Edwards;Steven R. Laplante

  • Looking forward to volume six.

    Jonathan Clayden

  • Barriers to rotation about the chiral axis of tertiary aromatic amides

    Anjum Ahmed;Ryan A. Bragg;Jonathan Clayden;Lai Wah Lai

  • Ultra-remote stereocontrol by conformational communication of information along a carbon chain

    Jonathan Clayden;Andrew Lund;Lluís Vallverdú;Madeleine Helliwell

  • Asymmetric synthesis of tertiary thiols and thioethers

    Jonathan Clayden;Paul MacLellan

  • Quaternary centres bearing nitrogen (α-tertiary amines) as products of molecular rearrangements

    Jonathan Clayden;Morgan Donnard;Julien Lefranc;Daniel J. Tetlow

  • Stereocontrol in Organic Synthesis Using the Diphenylphosphoryl Group

    Jonathan Clayden;Stuart Warren

  • Dynamic foldamer chemistry

    Bryden A F Le Bailly;Jonathan Clayden

  • Conformational photoswitching of a synthetic peptide foldamer bound within a phospholipid bilayer

    Matteo De Poli;Wojciech Zawodny;Ophélie Quinonero;Mark Lorch

  • Non-biaryl atropisomers: New classes of chiral reagents, auxiliaries, and ligands?

    Jonathan Clayden

  • Substituted diarylmethylamines by stereospecific intramolecular electrophilic arylation of lithiated ureas.

    Jonathan Clayden;Jérémy Dufour;Damian M. Grainger;Madeleine Helliwell

  • Atropisomeric Amides as Chiral Ligands: Using (−)-Sparteine-Directed Enantioselective Silylation to Control the Conformation of a Stereogenic Axis

    Jonathan Clayden;Paul Johnson;Jennifer H. Pink;Madeleine Helliwell

  • Atropisomers and near-atropisomers: achieving stereoselectivity by exploiting the conformational preferences of aromatic amides.

    Jonathan Clayden

  • Atropisomerie als Herausforderung in der Medikamentenentwicklung

    Jonathan Clayden;Wesley J. Moran;Paul J. Edwards;Steven R. LaPlante

  • Concerted Rotation in a Tertiary Aromatic Amide: Towards a Simple Molecular Gear

    Jonathan Clayden;Jennifer H. Pink

  • The Urea Renaissance

    Nicole Volz;Jonathan Clayden

  • Chemistry of domoic acid, isodomoic acids, and their analogues

    Jonathan Clayden;Benjamin Read;Katherine R. Hebditch

  • Ligand-modulated conformational switching in a fully synthetic membrane-bound receptor

    Francis G. A. Lister;Bryden A. F. Le Bailly;Simon J. Webb;Jonathan Clayden

  • Controlling Axial Conformation in 2-Arylpyridines and 1-Arylisoquinolines: Application to the Asymmetric Synthesis of QUINAP by Dynamic Thermodynamic Resolution

    Jonathan Clayden;Stephen P. Fletcher;Joseph J. W. McDouall;Stephen J. M. Rowbottom

  • Asymmetric α-arylation of amino acids.

    Daniel J. Leonard;John W. Ward;Jonathan Clayden

  • Biocatalytic Dynamic Kinetic Resolution for the Synthesis of Atropisomeric Biaryl N-Oxide Lewis Base Catalysts

    Samantha Staniland;Ralph W. Adams;Joseph J. W. McDouall;Irene Maffucci

  • Ultra-remote stereocontrol by conformational communication of;information along a carbon chain

    K Soai;J Clayden

Frequent Co-Authors

James Raftery
James Raftery University of Manchester
Ian H. Hillier
Ian H. Hillier University of Manchester
Gareth A. Morris
Gareth A. Morris University of Manchester
Nicholas J. Turner
Nicholas J. Turner University of Manchester
Michael Rowley
Michael Rowley Pharmaron (United Kingdom)
Gilles Guichard
Gilles Guichard Centre national de la recherche scientifique, CNRS
Peter O'Brien
Peter O'Brien University of York
Ewan W. Blanch
Ewan W. Blanch RMIT University
Alison Rodger
Alison Rodger Macquarie University
Mathias Nilsson
Mathias Nilsson University of Manchester

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