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Johan Staaf

Johan Staaf

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
15418
World Ranking
11233
National Ranking
164

Overview

Johan Staaf is affiliated with Lund University in Sweden and has an extensive publication record within the fields of biochemistry, genetics, molecular biology, and medicine. Their research primarily encompasses molecular biology, cancer research, oncology, pulmonary and respiratory medicine, and genetics.

Their work addresses several key topics including cancer genomics and diagnostics, RNA modifications and cancer, breast cancer treatment studies, cancer immunotherapy and biomarkers, epigenetics and DNA methylation, lung cancer treatments and mutations, and ferroptosis and cancer prognosis.

Recent research publications by Johan Staaf include the following papers:

  • RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer, 2022, npj Breast Cancer
  • Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms, 2021, Nature Cancer
  • Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers, 2020, Nature Communications
  • An Open-Source, Automated Tumor-Infiltrating Lymphocyte Algorithm for Prognosis in Triple-Negative Breast Cancer, 2021, Clinical Cancer Research
  • Precision cancer medicine: Concepts, current practice, and future developments, 2023, Journal of Internal Medicine

Frequent co-authors collaborating with Johan Staaf include:

  • Johan Vallon-Christersson
  • Maria Planck
  • Åke Borg
  • Anna Ehinger
  • Ana Bosch

Johan Staaf's publications appear often in the following venues:

  • Annals of Oncology
  • Cancer Research
  • Molecular Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)

Best Publications

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

    Helen Davies;Dominik D. Glodzik;Sandro S. Morganella;Lucy R. Yates

  • Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair

    Lao H Saal;Sofia K Gruvberger-Saal;Camilla Persson;Kristina Lövgren

  • GOBO: Gene Expression-Based Outcome for Breast Cancer Online.

    Markus Ringnér;Erik Fredlund;Jari Häkkinen;Åke Borg

  • Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns

    Karolina Holm;Cecilia Hegardt;Johan Staaf;Johan Vallon-Christersson

  • MiRNA expression in urothelial carcinomas: Important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31.

    Srinivas Veerla;David Lindgren;Anders Kvist;Attila Frigyesi

  • The topography of mutational processes in breast cancer genomes

    Sandro Morganella;Ludmil B. Alexandrov;Dominik Glodzik;Xueqing Zou

  • Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study.

    Johan Staaf;Dominik Glodzik;Dominik Glodzik;Dominik Glodzik;Ana Bosch;Johan Vallon-Christersson

  • Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

    Göran B Jönsson;Johan Staaf;Johan Vallon-Christersson;Markus Ringnér

  • Identification of New MicroRNAs in Paired Normal and Tumor Breast Tissue Suggests a Dual Role for the ERBB2/Her2 Gene

    Helena Persson;Anders Kvist;Natalia Rego;Johan Staaf

  • High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization.

    Göran B Jönsson;Johan Staaf;Eleonor Olsson;Markus Heidenblad

  • Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.

    David Lindgren;Gottfrid Sjödahl;Martin Lauss;Johan Staaf

  • Identification of Subtypes in Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer Reveals a Gene Signature Prognostic of Outcome

    Johan Staaf;Markus Ringnér;Johan Vallon-Christersson;Göran Jönsson

  • Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization.

    Göran B Jönsson;Tara L Naylor;Johan Vallon-Christersson;Johan Staaf

  • Molecular stratification of metastatic melanoma using gene expression profiling: prediction of survival outcome and benefit from molecular targeted therapy.

    Helena Cirenajwis;Henrik Ekedahl;Martin Lauss;Katja Harbst

  • Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays

    Johan Staaf;David Lindgren;Johan Vallon-Christersson;Anders Isaksson

  • Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios

    Johan Staaf;Johan Vallon-Christersson;David Lindgren;Gunnar Juliusson

  • High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer

    Johan Staaf;Göran Jönsson;Markus Ringnér;Johan Vallon-Christersson

  • Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.

    Jönsson G;Dahl C;Staaf J;Sandberg T

Frequent Co-Authors

Åke Borg
Åke Borg Lund University
Göran Jönsson
Göran Jönsson Lund University
Markus Ringnér
Markus Ringnér Lund University
Anna Karlsson
Anna Karlsson Skåne University Hospital
Serena Nik-Zainal
Serena Nik-Zainal University of Cambridge
Karin Jirström
Karin Jirström Lund University
Håkan Olsson
Håkan Olsson Lund University
David C. Christiani
David C. Christiani Harvard University
Sunil R. Lakhani
Sunil R. Lakhani University of Queensland
Helen Davies
Helen Davies University of Cambridge

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