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James A. Hamilton

James A. Hamilton

D-Index & Metrics

Chemistry

D-Index
75
Citations
16204
World Ranking
4556
National Ranking
1435

Overview

James A. Hamilton is affiliated with Boston University in the United States. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions to subfields such as Molecular Biology, Nutrition and Dietetics, Surgery, Radiology, Nuclear Medicine and Imaging, and Neurology.

The scientist's work covers a variety of topics, particularly in:

  • Fatty Acid Research and Health
  • Cell death mechanisms and regulation
  • Advanced Neuroimaging Techniques and Applications
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Photoacoustic and Ultrasonic Imaging
  • Angiogenesis and VEGF in Cancer
  • Cardiovascular Health and Disease Prevention

James A. Hamilton has published extensively in several scientific journals. Frequent publication venues include:

  • Atherosclerosis
  • The FASEB Journal
  • Proceedings of the National Academy of Sciences
  • Journal of Lipid Research
  • Journal of Translational Medicine

Among the recent research papers authored or coauthored by Hamilton are:

  • Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis, 2020, Proceedings of the National Academy of Sciences
  • SSO and other putative inhibitors of FA transport across membranes by CD36 disrupt intracellular metabolism, but do not affect FA translocation, 2020, Journal of Lipid Research
  • The brains of aged mice are characterized by altered tissue diffusion properties and cerebral microbleeds, 2020, Journal of Translational Medicine
  • Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin, 2020, Endocrinology
  • Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain, 2021, Journal of Medicinal Chemistry

Their frequent collaborators include Nasi Huang with 13 joint publications, Erik N. Taylor with 6, Richard J. Deckelbaum with 3, Martin Rübbelke with 2, and Margit Bauer with 2.

Best Publications

  • The Formation of Highly Soluble Oligomers of α-Synuclein Is Regulated by Fatty Acids and Enhanced in Parkinson's Disease

    Ronit Sharon;Ifat Bar-Joseph;Matthew P Frosch;Dominic M Walsh

  • Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule

    David P. Cistola;James A. Hamilton;David Jackson;Donald M. Small

  • Fatty acid transport: difficult or easy?

    James A. Hamilton

  • Location of High and Low Affinity Fatty Acid Binding Sites on Human Serum Albumin Revealed by NMR Drug-competition Analysis

    Jeffrey R. Simard;Patricia A. Zunszain;James A. Hamilton;Stephen Curry

  • Movement of fatty acids, fatty acid analogues, and bile acids across phospholipid bilayers.

    F Kamp;J A Hamilton;H V Westerhoff

  • How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?

    James A. Hamilton;Frits Kamp

  • FATTY ACID FLIP-FLOP IN PHOSPHOLIPID BILAYERS IS EXTREMELY FAST

    Frits Kamp;David Zakim;Fengli Zhang;Noa Noy

  • pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids

    Frits Kamp;James A. Hamilton

  • Transthyretin: a review from a structural perspective.

    J.A. Hamilton;M.D. Benson

  • In Vivo Molecular Imaging of Acute and Subacute Thrombosis Using a Fibrin-Binding Magnetic Resonance Imaging Contrast Agent

    René M. Botnar;Alexandra S. Perez;Sonia Witte;Andrea J. Wiethoff

  • Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy

    J. R. Simard;P. A. Zunszain;C.-E. Ha;J. S. Yang

  • The function of ubiquinone in Escherichia coli.

    G. B. Cox;N. A. Newton;F. Gibson;A. M. Snoswell

  • Phase behavior and bilayer properties of fatty acids: hydrated 1:1 acid-soaps

    David P. Cistola;David Atkinson;James A. Hamilton;Donald M. Small

  • Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy.

    J K Ho;H Moser;Y Kishimoto;J A Hamilton

  • How fatty acids of different chain length enter and leave cells by free diffusion

    Frits Kamp;James A. Hamilton

  • Fast flip-flop of cholesterol and fatty acids in membranes: implications for membrane transport proteins.

    James A Hamilton

  • Medium-chain versus long-chain triacylglycerol emulsion hydrolysis by lipoprotein lipase and hepatic lipase: implications for the mechanisms of lipase action.

    Richard J. Deckelbaum;James A. Hamilton;Asher Moser;Gunilla Bengtsson-Olivecrona

  • Solubilization and localization of triolein in phosphatidylcholine bilayers: a 13C NMR study.

    James A. Hamilton;Donald M. Small

  • Brain Uptake and Utilization of Fatty Acids, Lipids and Lipoproteins: Application to Neurological Disorders

    James A. Hamilton;Cecilia J. Hillard;Arthur A. Spector;Paul A. Watkins

  • A model for fatty acid transport into the brain

    James A. Hamilton;Kellen Brunaldi

  • Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes.

    Vandana Gupta;Shalender Bhasin;Wen Guo;Rajan Singh

Frequent Co-Authors

Donald Small
Donald Small Johns Hopkins University
Barbara E. Corkey
Barbara E. Corkey Boston University
Hong-Wen Deng
Hong-Wen Deng Tulane University
Stephen Locarnini
Stephen Locarnini Melbourne Health
Robert G. Gish
Robert G. Gish University of Nevada Reno
James C. Sacchettini
James C. Sacchettini Texas A&M University
Ching-Lung Lai
Ching-Lung Lai University of Hong Kong
Paul A. Watkins
Paul A. Watkins Kennedy Krieger Institute
Albert J. Shih
Albert J. Shih University of Michigan–Ann Arbor

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