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Biology and Biochemistry

D-Index
58
Citations
11797
World Ranking
13193
National Ranking
5623

Overview

Jacek Hawiger is affiliated with Vanderbilt University in the United States and has contributed to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Immunology and Allergy, Dermatology, Nutrition and Dietetics, and Epidemiology.

The scientist's research encompasses topics such as RNA Research and Splicing, Dermatology and Skin Diseases, Cell Adhesion Molecules Research, RNA Interference and Gene Delivery, Allergic Rhinitis and Sensitization, Asthma and respiratory diseases, and Inflammasome and immune disorders.

Recent publications by Jacek Hawiger include the following:

  • EGF receptor-mediated FUS phosphorylation promotes its nuclear translocation and fibrotic signaling, 2020, The Journal of Cell Biology
  • Genomic control of inflammation in experimental atopic dermatitis, 2022, Scientific Reports
  • Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles, 2021, Scientific Reports
  • Activation of thousands of genes in the lungs and kidneys by sepsis is countered by the selective nuclear blockade, 2023, Frontiers in Immunology
  • Cytoplasmic retention of the DNA/RNA-binding protein FUS ameliorates organ fibrosis in mice, 2024, Journal of Clinical Investigation

Jacek Hawiger's collaborations include frequent co-authorship with J Zienkiewicz, Huan Qiao, Manuel Chiusa, Ming-Zhi Zhang, and Raymond C. Harris. These collaborations have contributed to advances in various immunological and molecular biology topics.

The scientist's work has been published repeatedly in venues such as Scientific Reports and Frontiers in Immunology, as well as The Journal of Cell Biology, Journal of Clinical Investigation, and Skin Health and Disease.

Best Publications

  • Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence

    Yao-Zhong Lin;SongYi Yao;Ruth Ann Veach;Troy R. Torgerson

  • Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.

    G A FitzGerald;J A Oates;J Hawiger;R L Maas

  • Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the gamma chain.

    Marek Kloczewiak;Sheila Timmons;Thomas J. Lukas;Jacek Hawiger

  • Measurement of fibrinogen and fibrin degradation products in serum by staphylococcal clumping test

    Hawiger J;Niewiarowski S;Gurewich;Thomas Dp

  • Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis.

    Daewoong Jo;Danya Liu;Shan Yao;Robert D Collins

  • Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate.

    H J Weiss;J Hawiger;Z M Ruggeri;V T Turitto

  • Factor IX is activated in vivo by the tissue factor mechanism.

    KA Bauer;BL Kass;H ten Cate;JJ Hawiger

  • Innate immunity and inflammation: a transcriptional paradigm.

    Jacek Hawiger

  • Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells.

    S R Cordle;R Donald;M A Read;J Hawiger

  • Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets.

    T Fujimoto;S Ohara;J Hawiger

  • Regulation of NF-κB, AP-1, NFAT, and STAT1 Nuclear Import in T Lymphocytes by Noninvasive Delivery of Peptide Carrying the Nuclear Localization Sequence of NF-κB p50

    Troy R. Torgerson;Ann D. Colosia;John P. Donahue;Yao Zhong Lin

  • Noninvasive intracellular delivery of functional peptides and proteins.

    Jacek Hawiger

  • gamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptors.

    J Hawiger;S Timmons;M Kloczewiak;D D Strong

  • The Tax Oncoprotein of Human T-cell Leukemia Virus Type 1 Associates with and Persistently Activates IκB Kinases Containing IKKα and IKKβ

    Zhi Liang Chu;Joseph A DiDonato;Jacek Hawiger;Dean W. Ballard

  • Localization of a site interacting with human platelet receptor on carboxy-terminal segment of human fibrinogen γ chain

    Marek Kloczewiak;Sheila Timmons;Jacek Hawiger

  • Identification of a region of human fibrinogen interacting with staphylococcal clumping factor.

    J. Hawiger;S. Timmons;D. D. Strong;B. A. Cottrell

  • Formation and regulation of platelet and fibrin hemostatic plug

    Jacek Hawiger

  • Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs

    Xue-Yan Liu;Sheila Timmons;Yao-Zhong Lin;Jacek Hawiger

  • Nuclear import of proinflammatory transcription factors is required for massive liver apoptosis induced by bacterial lipopolysaccharide.

    Danya Liu;Chunsheng Li;Yiliu Chen;Christie Burnett

  • Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells

    Margaret A. Read;Susan R. Cordle;Ruth A. Veach;Cherlyn D. Carlisle

Frequent Co-Authors

Russell F. Doolittle
Russell F. Doolittle University of California, San Diego
John A. Oates
John A. Oates Vanderbilt University
Kenneth A. Bauer
Kenneth A. Bauer Beth Israel Deaconess Medical Center
Robert D. Rosenberg
Robert D. Rosenberg Technical University of Munich
Daniel G. Colley
Daniel G. Colley University of Georgia
Kelli L. Boyd
Kelli L. Boyd Vanderbilt University Medical Center
Sebastian Joyce
Sebastian Joyce Vanderbilt University Medical Center
Derya Unutmaz
Derya Unutmaz University of Connecticut
Dean W. Ballard
Dean W. Ballard Vanderbilt University
Richard L. Maas
Richard L. Maas Brigham and Women's Hospital

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